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Q55GH4

- GYS_DICDI

UniProt

Q55GH4 - GYS_DICDI

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Protein
Glycogen [starch] synthase
Gene
glcS, DDB_G0267674
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Transfers the glycosyl residue from UDPG to the non-reducing end of alpha-1,4-glucan.1 Publication

Catalytic activityi

UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611UDP-glucose By similarity

GO - Molecular functioni

  1. glycogen (starch) synthase activity Source: dictyBase

GO - Biological processi

  1. autophagic vacuole assembly Source: dictyBase
  2. glycogen biosynthetic process Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen [starch] synthase (EC:2.4.1.11)
Gene namesi
Name:glcS
ORF Names:DDB_G0267674
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0267674. glcS.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878878Glycogen [starch] synthase
PRO_0000355639Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231962.

Structurei

3D structure databases

ProteinModelPortaliQ55GH4.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi666 – 67510Poly-Gln
Compositional biasi693 – 861169Thr-rich
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0438.
KOiK00693.
OMAiYIAHFHE.
PhylomeDBiQ55GH4.

Family and domain databases

InterProiIPR008631. Glycogen_synth.
[Graphical view]
PANTHERiPTHR10176. PTHR10176. 1 hit.
PfamiPF05693. Glycogen_syn. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55GH4-1 [UniParc]FASTAAdd to Basket

« Hide

MIFGTPNSTF LENRLGSSTG MPFSSATSLN SGVDQMMNEL NIQQPTSHTV    50
LFDLSWEVAK KVGGIYTVLK TKAPVTVEEY KSRYALIGPY NASTAPTEFE 100
PLIPGPLSSP IIENMMKKYG IHVHFGKWLV EGYPKVFLID LHSSMHKLGE 150
WRWDLMSGFE QAGDNETNET IVFGYQSALL LKEFAEANPN DKYIAHFHEW 200
QASVGLILLK KWKVPVSTIF TTHATLLGRY LAAGGVDLYN QMQVLNMDFE 250
ASKRGIYHRH WIEKKSAADS HVFTTVSEIT GYESEHILMR KPDVILPNGL 300
KLDKFTALHE FQNLHAKYKG VLNEFVRGHF YGHYSDFDLD NTLYVFTAGR 350
HEYFNKGVDM FLDSLAGLNK LLQQSGSKMT VVAFIIMPAA TNNFNVESLK 400
GHSYLKDMRR TCNTIVEAMG ERLFEATSRG KMISPEELLS QEDLVMLKRR 450
IFALKQKSSG PPVVTHNMIN DNDEILQHIR RIKLFNSQED RVKVIYHPEF 500
LTSTNPLIPL DYTEFVRGCH LGIFPSYYEP FGMTPAECCA SGCPSITSNL 550
TGFANYMSRA LQDTDSKGIF IVDRRFKSSR ETVDQMTQYL WKFTQLDRRQ 600
RIELRNATEK LSELLDWRTL GKFYKTARAL ALERAFPPKP ISRSPSPSPS 650
SSLKLSTGLS NQIELQQQQQ QQQPQPIGTT INLIPPSSNV SVTPTTTPTT 700
TTTATTATTA PITTPKPNVI PINTGKENIT LLSPNSMSSL LSDSLNEFKK 750
QQQQQQQSKT PTTPTTTSTT TTTPSTTAAA TNKSVLSNPT PTPSPNTSSF 800
IPTNKGSTAT TTTTTATPTP TPSNNTNGKP FNPIEALTKS NSSSNFATTS 850
TASVNTNNGG TNSPVSKSIP IPSSKSLK 878
Length:878
Mass (Da):97,515
Last modified:May 24, 2005 - v1
Checksum:iCA7F313E52021AB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73290.1.
RefSeqiXP_647210.1. XM_642118.1.

Genome annotation databases

EnsemblProtistsiDDB0231962; DDB0231962; DDB_G0267674.
GeneIDi8616014.
KEGGiddi:DDB_G0267674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73290.1 .
RefSeqi XP_647210.1. XM_642118.1.

3D structure databases

ProteinModelPortali Q55GH4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231962.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231962 ; DDB0231962 ; DDB_G0267674 .
GeneIDi 8616014.
KEGGi ddi:DDB_G0267674.

Organism-specific databases

dictyBasei DDB_G0267674. glcS.

Phylogenomic databases

eggNOGi COG0438.
KOi K00693.
OMAi YIAHFHE.
PhylomeDBi Q55GH4.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

InterProi IPR008631. Glycogen_synth.
[Graphical view ]
PANTHERi PTHR10176. PTHR10176. 1 hit.
Pfami PF05693. Glycogen_syn. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation and characterization of glycogen synthase in Dictyostelium discoideum."
    Williamson B.D., Favis R., Brickey D.A., Rutherford C.L.
    Dev. Genet. 19:350-364(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE, FUNCTION.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiGYS_DICDI
AccessioniPrimary (citable) accession number: Q55GH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: May 24, 2005
Last modified: September 3, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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