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Q55GH4 (GYS_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen [starch] synthase

EC=2.4.1.11
Gene names
Name:glcS
ORF Names:DDB_G0267674
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length878 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the glycosyl residue from UDPG to the non-reducing end of alpha-1,4-glucan. Ref.1

Catalytic activity

UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

Pathway

Glycan biosynthesis; glycogen biosynthesis.

Sequence similarities

Belongs to the glycosyltransferase 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 878878Glycogen [starch] synthase
PRO_0000355639

Regions

Compositional bias666 – 67510Poly-Gln
Compositional bias693 – 861169Thr-rich

Sites

Binding site611UDP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55GH4 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: CA7F313E52021AB3

FASTA87897,515
        10         20         30         40         50         60 
MIFGTPNSTF LENRLGSSTG MPFSSATSLN SGVDQMMNEL NIQQPTSHTV LFDLSWEVAK 

        70         80         90        100        110        120 
KVGGIYTVLK TKAPVTVEEY KSRYALIGPY NASTAPTEFE PLIPGPLSSP IIENMMKKYG 

       130        140        150        160        170        180 
IHVHFGKWLV EGYPKVFLID LHSSMHKLGE WRWDLMSGFE QAGDNETNET IVFGYQSALL 

       190        200        210        220        230        240 
LKEFAEANPN DKYIAHFHEW QASVGLILLK KWKVPVSTIF TTHATLLGRY LAAGGVDLYN 

       250        260        270        280        290        300 
QMQVLNMDFE ASKRGIYHRH WIEKKSAADS HVFTTVSEIT GYESEHILMR KPDVILPNGL 

       310        320        330        340        350        360 
KLDKFTALHE FQNLHAKYKG VLNEFVRGHF YGHYSDFDLD NTLYVFTAGR HEYFNKGVDM 

       370        380        390        400        410        420 
FLDSLAGLNK LLQQSGSKMT VVAFIIMPAA TNNFNVESLK GHSYLKDMRR TCNTIVEAMG 

       430        440        450        460        470        480 
ERLFEATSRG KMISPEELLS QEDLVMLKRR IFALKQKSSG PPVVTHNMIN DNDEILQHIR 

       490        500        510        520        530        540 
RIKLFNSQED RVKVIYHPEF LTSTNPLIPL DYTEFVRGCH LGIFPSYYEP FGMTPAECCA 

       550        560        570        580        590        600 
SGCPSITSNL TGFANYMSRA LQDTDSKGIF IVDRRFKSSR ETVDQMTQYL WKFTQLDRRQ 

       610        620        630        640        650        660 
RIELRNATEK LSELLDWRTL GKFYKTARAL ALERAFPPKP ISRSPSPSPS SSLKLSTGLS 

       670        680        690        700        710        720 
NQIELQQQQQ QQQPQPIGTT INLIPPSSNV SVTPTTTPTT TTTATTATTA PITTPKPNVI 

       730        740        750        760        770        780 
PINTGKENIT LLSPNSMSSL LSDSLNEFKK QQQQQQQSKT PTTPTTTSTT TTTPSTTAAA 

       790        800        810        820        830        840 
TNKSVLSNPT PTPSPNTSSF IPTNKGSTAT TTTTTATPTP TPSNNTNGKP FNPIEALTKS 

       850        860        870 
NSSSNFATTS TASVNTNNGG TNSPVSKSIP IPSSKSLK 

« Hide

References

« Hide 'large scale' references
[1]"Isolation and characterization of glycogen synthase in Dictyostelium discoideum."
Williamson B.D., Favis R., Brickey D.A., Rutherford C.L.
Dev. Genet. 19:350-364(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE, FUNCTION.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000003 Genomic DNA. Translation: EAL73290.1.

3D structure databases

ProteinModelPortalQ55GH4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231962.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231962; DDB0231962; DDB_G0267674.
KEGGddi:DDB_G0267674.

Organism-specific databases

dictyBaseDDB_G0267674. glcS.

Phylogenomic databases

eggNOGCOG0438.
KOK00693.
OMAHCARTEM.
PhylomeDBQ55GH4.
ProtClustDBCLSZ2431516.

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

InterProIPR008631. Glycogen_synth.
[Graphical view]
PANTHERPTHR10176. PTHR10176. 1 hit.
PfamPF05693. Glycogen_syn. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGYS_DICDI
AccessionPrimary (citable) accession number: Q55GH4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase