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Q55GH4

- GYS_DICDI

UniProt

Q55GH4 - GYS_DICDI

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Protein

Glycogen [starch] synthase

Gene

glcS

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Transfers the glycosyl residue from UDPG to the non-reducing end of alpha-1,4-glucan.1 Publication

Catalytic activityi

UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611UDP-glucoseBy similarity

GO - Molecular functioni

  1. glycogen (starch) synthase activity Source: dictyBase

GO - Biological processi

  1. autophagic vacuole assembly Source: dictyBase
  2. glycogen biosynthetic process Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen [starch] synthase (EC:2.4.1.11)
Gene namesi
Name:glcS
ORF Names:DDB_G0267674
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0267674. glcS.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878878Glycogen [starch] synthasePRO_0000355639Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231962.

Structurei

3D structure databases

ProteinModelPortaliQ55GH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi666 – 67510Poly-Gln
Compositional biasi693 – 861169Thr-richAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyltransferase 3 family.Curated

Phylogenomic databases

eggNOGiCOG0438.
InParanoidiQ55GH4.
KOiK00693.
OMAiYIAHFHE.
PhylomeDBiQ55GH4.

Family and domain databases

InterProiIPR008631. Glycogen_synth.
[Graphical view]
PANTHERiPTHR10176. PTHR10176. 1 hit.
PfamiPF05693. Glycogen_syn. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55GH4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIFGTPNSTF LENRLGSSTG MPFSSATSLN SGVDQMMNEL NIQQPTSHTV
60 70 80 90 100
LFDLSWEVAK KVGGIYTVLK TKAPVTVEEY KSRYALIGPY NASTAPTEFE
110 120 130 140 150
PLIPGPLSSP IIENMMKKYG IHVHFGKWLV EGYPKVFLID LHSSMHKLGE
160 170 180 190 200
WRWDLMSGFE QAGDNETNET IVFGYQSALL LKEFAEANPN DKYIAHFHEW
210 220 230 240 250
QASVGLILLK KWKVPVSTIF TTHATLLGRY LAAGGVDLYN QMQVLNMDFE
260 270 280 290 300
ASKRGIYHRH WIEKKSAADS HVFTTVSEIT GYESEHILMR KPDVILPNGL
310 320 330 340 350
KLDKFTALHE FQNLHAKYKG VLNEFVRGHF YGHYSDFDLD NTLYVFTAGR
360 370 380 390 400
HEYFNKGVDM FLDSLAGLNK LLQQSGSKMT VVAFIIMPAA TNNFNVESLK
410 420 430 440 450
GHSYLKDMRR TCNTIVEAMG ERLFEATSRG KMISPEELLS QEDLVMLKRR
460 470 480 490 500
IFALKQKSSG PPVVTHNMIN DNDEILQHIR RIKLFNSQED RVKVIYHPEF
510 520 530 540 550
LTSTNPLIPL DYTEFVRGCH LGIFPSYYEP FGMTPAECCA SGCPSITSNL
560 570 580 590 600
TGFANYMSRA LQDTDSKGIF IVDRRFKSSR ETVDQMTQYL WKFTQLDRRQ
610 620 630 640 650
RIELRNATEK LSELLDWRTL GKFYKTARAL ALERAFPPKP ISRSPSPSPS
660 670 680 690 700
SSLKLSTGLS NQIELQQQQQ QQQPQPIGTT INLIPPSSNV SVTPTTTPTT
710 720 730 740 750
TTTATTATTA PITTPKPNVI PINTGKENIT LLSPNSMSSL LSDSLNEFKK
760 770 780 790 800
QQQQQQQSKT PTTPTTTSTT TTTPSTTAAA TNKSVLSNPT PTPSPNTSSF
810 820 830 840 850
IPTNKGSTAT TTTTTATPTP TPSNNTNGKP FNPIEALTKS NSSSNFATTS
860 870
TASVNTNNGG TNSPVSKSIP IPSSKSLK
Length:878
Mass (Da):97,515
Last modified:May 24, 2005 - v1
Checksum:iCA7F313E52021AB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73290.1.
RefSeqiXP_647210.1. XM_642118.1.

Genome annotation databases

EnsemblProtistsiDDB0231962; DDB0231962; DDB_G0267674.
GeneIDi8616014.
KEGGiddi:DDB_G0267674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73290.1 .
RefSeqi XP_647210.1. XM_642118.1.

3D structure databases

ProteinModelPortali Q55GH4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231962.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231962 ; DDB0231962 ; DDB_G0267674 .
GeneIDi 8616014.
KEGGi ddi:DDB_G0267674.

Organism-specific databases

dictyBasei DDB_G0267674. glcS.

Phylogenomic databases

eggNOGi COG0438.
InParanoidi Q55GH4.
KOi K00693.
OMAi YIAHFHE.
PhylomeDBi Q55GH4.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

InterProi IPR008631. Glycogen_synth.
[Graphical view ]
PANTHERi PTHR10176. PTHR10176. 1 hit.
Pfami PF05693. Glycogen_syn. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation and characterization of glycogen synthase in Dictyostelium discoideum."
    Williamson B.D., Favis R., Brickey D.A., Rutherford C.L.
    Dev. Genet. 19:350-364(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE, FUNCTION.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiGYS_DICDI
AccessioniPrimary (citable) accession number: Q55GH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3