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Protein

Myotrophin homolog

Gene

mtpn

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May regulate NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).By similarity

GO - Molecular functioni

  • protein complex binding Source: dictyBase

GO - Biological processi

  • actin cytoskeleton organization Source: dictyBase
  • negative regulation of barbed-end actin filament capping Source: dictyBase

Names & Taxonomyi

Protein namesi
Recommended name:
Myotrophin homolog
Gene namesi
Name:mtpn
ORF Names:DDB_G0268038
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0268038. mtpn.

Subcellular locationi

Q55FM5:

GO - Cellular componenti

  • cytoplasm Source: dictyBase
  • nucleus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003306601 – 120Myotrophin homologAdd BLAST120

Proteomic databases

PaxDbiQ55FM5.

Interactioni

GO - Molecular functioni

  • protein complex binding Source: dictyBase

Protein-protein interaction databases

STRINGi44689.DDB0305263.

Structurei

3D structure databases

ProteinModelPortaliQ55FM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 31ANK 1Add BLAST31
Repeati36 – 65ANK 2Add BLAST30
Repeati69 – 98ANK 3Add BLAST30

Sequence similaritiesi

Belongs to the myotrophin family.Curated

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG4214. Eukaryota.
ENOG4111U90. LUCA.
InParanoidiQ55FM5.
OMAiKNIDVNQ.
PhylomeDBiQ55FM5.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
SMARTiView protein in SMART
SM00248. ANK. 2 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.

Sequencei

Sequence statusi: Complete.

Q55FM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEQNDFTWA VKNGDIANVK KSVEAKKDLI SITDGNKRGP CHWAADFNQV
60 70 80 90 100
EVLEYLISKG AKFDNTDDYG ITPLLAAVYE GHTGAVELLV KKGANKSVVG
110 120
PDGQTAYDAA EKADIKALLK
Length:120
Mass (Da):12,998
Last modified:May 24, 2005 - v1
Checksum:i050C0FAD43785C22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73472.1.
RefSeqiXP_647508.1. XM_642416.1.

Genome annotation databases

EnsemblProtistsiEAL73472; EAL73472; DDB_G0268038.
GeneIDi8616315.
KEGGiddi:DDB_G0268038.

Similar proteinsi

Entry informationi

Entry nameiMTPN_DICDI
AccessioniPrimary (citable) accession number: Q55FM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families