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Protein

Probable serine/threonine-protein kinase DDB_G0268078

Gene

DDB_G0268078

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei125Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase DDB_G0268078 (EC:2.7.11.22)
Gene namesi
ORF Names:DDB_G0268078
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0268078.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003589031 – 507Probable serine/threonine-protein kinase DDB_G0268078Add BLAST507

Proteomic databases

PaxDbiQ55FJ6.
PRIDEiQ55FJ6.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0229430.

Structurei

3D structure databases

ProteinModelPortaliQ55FJ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 286Protein kinasePROSITE-ProRule annotationAdd BLAST283

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi326 – 336Poly-AsnAdd BLAST11
Compositional biasi381 – 392Poly-AsnAdd BLAST12
Compositional biasi415 – 419Poly-Gln5
Compositional biasi430 – 449Pro-richAdd BLAST20
Compositional biasi453 – 467Poly-GlnAdd BLAST15

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0661. Eukaryota.
ENOG410XPBB. LUCA.
InParanoidiQ55FJ6.
KOiK08829.
OMAiICTIMGS.
PhylomeDBiQ55FJ6.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55FJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKYQFIKQV GDGAYGDVIK AIDVKTGEIV AIKRMKKKFS DWKECIQLRE
60 70 80 90 100
IKALKKLKHP NIVKLLEIIL ERDELFFVFE YLENNLYESI KDRTKLLPET
110 120 130 140 150
TIRNIIYQIL QALHFMHTNG FFHRDLKPEN IMLVGERLKI ADFGLAREIE
160 170 180 190 200
SKPPFTDYIS TRWYRAPEVL LRCTYYNAPI DIWAVGAIMA ELYSLKPMFP
210 220 230 240 250
GSSEIDQLFK ICTIMGSPTS ATWIDGIKLA NSMGFTFPNV QPPSINPLST
260 270 280 290 300
LLPNANQDAI ELITDLLQYD PLKRPTPLQA LQHRYFKVSI PSSILLKPNF
310 320 330 340 350
IELSNKYLIK NGYINNNINN NSNYSNNNNN NNLNSNSENL NNVNKNNQQP
360 370 380 390 400
HSPQKIQTPK PKNSFLRKSR YSYLNNVSLE NVNNNNNNYN SNTTSGYYNQ
410 420 430 440 450
KLDSTPRLSP RIVRQQQQQI LLPLIIQQQP PPQSQPPQSQ PPPQSQPPPI
460 470 480 490 500
LTQQQQQQQQ QQQQQQQLPS KTTIYHNTNH LNAPIPPNHQ RGISPQFYNE

TTNNSKL
Length:507
Mass (Da):58,510
Last modified:May 24, 2005 - v1
Checksum:i26AA757DBDFA9841
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73492.1.
RefSeqiXP_647537.1. XM_642445.1.

Genome annotation databases

EnsemblProtistsiEAL73492; EAL73492; DDB_G0268078.
GeneIDi8616344.
KEGGiddi:DDB_G0268078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000003 Genomic DNA. Translation: EAL73492.1.
RefSeqiXP_647537.1. XM_642445.1.

3D structure databases

ProteinModelPortaliQ55FJ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0229430.

Proteomic databases

PaxDbiQ55FJ6.
PRIDEiQ55FJ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL73492; EAL73492; DDB_G0268078.
GeneIDi8616344.
KEGGiddi:DDB_G0268078.

Organism-specific databases

dictyBaseiDDB_G0268078.

Phylogenomic databases

eggNOGiKOG0661. Eukaryota.
ENOG410XPBB. LUCA.
InParanoidiQ55FJ6.
KOiK08829.
OMAiICTIMGS.
PhylomeDBiQ55FJ6.

Miscellaneous databases

PROiQ55FJ6.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY8078_DICDI
AccessioniPrimary (citable) accession number: Q55FJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 24, 2005
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.