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Q55FJ6

- Y8078_DICDI

UniProt

Q55FJ6 - Y8078_DICDI

Protein

Probable serine/threonine-protein kinase DDB_G0268078

Gene

DDB_G0268078

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei33 – 331ATPPROSITE-ProRule annotation
    Active sitei125 – 1251Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase DDB_G0268078 (EC:2.7.11.22)
    Gene namesi
    ORF Names:DDB_G0268078
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0268078.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 507507Probable serine/threonine-protein kinase DDB_G0268078PRO_0000358903Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0229430.

    Structurei

    3D structure databases

    ProteinModelPortaliQ55FJ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 286283Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi326 – 33611Poly-AsnAdd
    BLAST
    Compositional biasi381 – 39212Poly-AsnAdd
    BLAST
    Compositional biasi415 – 4195Poly-Gln
    Compositional biasi430 – 44920Pro-richAdd
    BLAST
    Compositional biasi453 – 46715Poly-GlnAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08829.
    OMAiSINIARC.
    PhylomeDBiQ55FJ6.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q55FJ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKYQFIKQV GDGAYGDVIK AIDVKTGEIV AIKRMKKKFS DWKECIQLRE    50
    IKALKKLKHP NIVKLLEIIL ERDELFFVFE YLENNLYESI KDRTKLLPET 100
    TIRNIIYQIL QALHFMHTNG FFHRDLKPEN IMLVGERLKI ADFGLAREIE 150
    SKPPFTDYIS TRWYRAPEVL LRCTYYNAPI DIWAVGAIMA ELYSLKPMFP 200
    GSSEIDQLFK ICTIMGSPTS ATWIDGIKLA NSMGFTFPNV QPPSINPLST 250
    LLPNANQDAI ELITDLLQYD PLKRPTPLQA LQHRYFKVSI PSSILLKPNF 300
    IELSNKYLIK NGYINNNINN NSNYSNNNNN NNLNSNSENL NNVNKNNQQP 350
    HSPQKIQTPK PKNSFLRKSR YSYLNNVSLE NVNNNNNNYN SNTTSGYYNQ 400
    KLDSTPRLSP RIVRQQQQQI LLPLIIQQQP PPQSQPPQSQ PPPQSQPPPI 450
    LTQQQQQQQQ QQQQQQQLPS KTTIYHNTNH LNAPIPPNHQ RGISPQFYNE 500
    TTNNSKL 507
    Length:507
    Mass (Da):58,510
    Last modified:May 24, 2005 - v1
    Checksum:i26AA757DBDFA9841
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000003 Genomic DNA. Translation: EAL73492.1.
    RefSeqiXP_647537.1. XM_642445.1.

    Genome annotation databases

    EnsemblProtistsiDDB0229430; DDB0229430; DDB_G0268078.
    GeneIDi8616344.
    KEGGiddi:DDB_G0268078.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000003 Genomic DNA. Translation: EAL73492.1 .
    RefSeqi XP_647537.1. XM_642445.1.

    3D structure databases

    ProteinModelPortali Q55FJ6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0229430.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0229430 ; DDB0229430 ; DDB_G0268078 .
    GeneIDi 8616344.
    KEGGi ddi:DDB_G0268078.

    Organism-specific databases

    dictyBasei DDB_G0268078.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08829.
    OMAi SINIARC.
    PhylomeDBi Q55FJ6.

    Miscellaneous databases

    PROi Q55FJ6.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiY8078_DICDI
    AccessioniPrimary (citable) accession number: Q55FJ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3