Reviewed,
UniProtKB/Swiss-Prot Q55FI1 (GABT_DICDI)
Last modified
November 3, 2009.
Version 34.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 4-aminobutyrate aminotransferase EC=2.6.1.19 Alternative name(s): Gamma-amino-N-butyrate transaminase Short name=GABA transaminase GABA aminotransferase Short name=GABA-AT | ||||
| Gene names |
| ||||
| Organism | Dictyostelium discoideum (Slime mold) [Complete proteome] | ||||
| Taxonomic identifier | 44689 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 495 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate. |
| Cofactor | Pyridoxal phosphate By similarity. |
| Sequence similarities | Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Pyridoxal phosphate |
| Molecular function | Aminotransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | 4-aminobutyrate transaminase complex Inferred from sequence or structural similarity. Source: UniProtKB |
| Molecular function | 4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: EC protein homodimerization activityInferred from sequence or structural similarity. Source: UniProtKB pyridoxal phosphate bindingInferred from sequence or structural similarity. Source: UniProtKB |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. Kuspa A.Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AAFI02000003 Genomic DNA. Translation: EAL73505.1. | |
| RefSeq | XP_647552.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q55FI1. |
Genome annotation databases | |
| GeneID | 3398547. |
| GenomeReviews | Gene locus gabT in contig CM000150_GR. |
| KEGG | ddi:DDB_0231448. |
Organism-specific databases | |
| dictyBase | DDB_G0268104. gabT. |
Phylogenomic databases | |
| OMA | KERGQRG. |
Enzyme and pathway databases | |
| BRENDA | 2.6.1.19. 424. |
Family and domain databases | |
| InterPro | IPR004631. 4NH2But_aminotransferase_euk. IPR005814. Aminotrans_3. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view] |
| Gene3D | G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. |
| PANTHER | PTHR11986. Aminotrans_3. 1 hit. PTHR11986:SF6. GABAtrns_euk. 1 hit. |
| Pfam | PF00202. Aminotran_3. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00699. GABAtrns_euk. 1 hit. |
| PROSITE | PS00600. AA_TRANSFER_CLASS_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GABT_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q55FI1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| SIMILARITY comments Index of protein domains and families |

Clusters with


