Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q55E72

- PKS1_DICDI

UniProt

Q55E72 - PKS1_DICDI

Protein

Probable polyketide synthase 1

Gene

stlA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Probable polyketide synthase By similarity. Produces only acylpyrones; in vitro.By similarity1 Publication

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

    Cofactori

    Binds 1 phosphopantetheine covalently.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei180 – 1801For beta-ketoacyl synthase activityPROSITE-ProRule annotation
    Active sitei682 – 6821For acyl/malonyl transferase activityPROSITE-ProRule annotation
    Active sitei2930 – 29301PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC
    2. oxidoreductase activity Source: InterPro

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
    2. polyketide biosynthetic process Source: dictyBase
    3. resorcinol metabolic process Source: dictyBase
    4. sorocarp spore cell differentiation Source: dictyBase
    5. sorocarp stalk cell differentiation Source: dictyBase
    6. sorus development Source: dictyBase

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable polyketide synthase 1
    Short name:
    dipks1
    Including the following 2 domains:
    Polyketide synthase stlA (EC:2.3.1.-)
    Chalcone synthase stlA (EC:2.3.1.74)
    Alternative name(s):
    Steely1
    Gene namesi
    Name:stlA
    Synonyms:pks1
    ORF Names:DDB_G0269364
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0269364. stlA.

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: dictyBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 31473147Probable polyketide synthase 1PRO_0000377901Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2605 – 26051O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation

    Keywords - PTMi

    Phosphopantetheine, Phosphoprotein

    Proteomic databases

    PRIDEiQ55E72.

    Expressioni

    Developmental stagei

    Expressed during development. Expressed maximally in early development before cellular aggregation.1 Publication

    Interactioni

    Subunit structurei

    Homodimer.1 Publication

    Protein-protein interaction databases

    STRINGi44689.DDBDRAFT_0190208.

    Structurei

    Secondary structure

    1
    3147
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi2788 – 27958
    Beta strandi2797 – 27993
    Helixi2803 – 281311
    Helixi2818 – 282912
    Helixi2845 – 28473
    Helixi2849 – 28546
    Helixi2857 – 288327
    Helixi2887 – 28893
    Beta strandi2892 – 28998
    Helixi2906 – 29149
    Beta strandi2921 – 29277
    Helixi2929 – 29313
    Helixi2932 – 294413
    Beta strandi2951 – 29588
    Helixi2961 – 29633
    Beta strandi2967 – 29693
    Helixi2970 – 29789
    Beta strandi2982 – 299110
    Beta strandi3000 – 300910
    Beta strandi3016 – 30227
    Beta strandi3025 – 30306
    Helixi3034 – 305320
    Turni3054 – 30563
    Beta strandi3063 – 30708
    Helixi3075 – 308410
    Helixi3089 – 30924
    Helixi3093 – 310210
    Helixi3108 – 311811
    Beta strandi3125 – 31339
    Turni3134 – 31363
    Beta strandi3137 – 31459

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2H84X-ray2.90A/B2776-3147[»]
    ProteinModelPortaliQ55E72.
    SMRiQ55E72. Positions 2785-3147.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ55E72.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2573 – 264270Acyl carrierPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni161 – 21454Beta-ketoacyl synthaseAdd
    BLAST
    Regioni672 – 70534Acyl/malonyl transferaseAdd
    BLAST
    Regioni2789 – 3147359Chalcone synthaseAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi355 – 3628Poly-Asp
    Compositional biasi470 – 4789Poly-Asn
    Compositional biasi561 – 5644Poly-Ser
    Compositional biasi576 – 5816Poly-Thr
    Compositional biasi1684 – 16885Poly-Ser
    Compositional biasi2097 – 21004Poly-Gln
    Compositional biasi2647 – 26559Poly-Asn
    Compositional biasi2770 – 27745Poly-Gln

    Domaini

    Modular protein possessing six classical catalytic domains and a type III polyketide synthase domain. May facilitate covalent transfer of steely N-terminal acyl products directly to the C-terminal type III PKS active sites, which catalyze both iterative polyketide extension and cyclization.

    Sequence similaritiesi

    In the C-terminal section; belongs to the chalcone/stilbene synthases family.Curated
    Contains 1 acyl carrier domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG3424.
    InParanoidiQ55E72.
    OMAiNDDSINH.
    PhylomeDBiQ55E72.

    Family and domain databases

    Gene3Di1.10.1200.10. 1 hit.
    3.40.366.10. 2 hits.
    3.40.47.10. 4 hits.
    3.40.50.150. 1 hit.
    3.40.50.720. 2 hits.
    3.90.180.10. 1 hit.
    InterProiIPR001227. Ac_transferase_dom.
    IPR009081. Acyl_carrier_prot-like.
    IPR014043. Acyl_transferase.
    IPR016035. Acyl_Trfase/lysoPLipase.
    IPR013154. ADH_GroES-like.
    IPR012328. Chalcone/stilbene_synth_C.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011032. GroES-like.
    IPR018201. Ketoacyl_synth_AS.
    IPR014031. Ketoacyl_synth_C.
    IPR014030. Ketoacyl_synth_N.
    IPR016036. Malonyl_transacylase_ACP-bd.
    IPR013217. Methyltransf_12.
    IPR016040. NAD(P)-bd_dom.
    IPR020801. PKS_acyl_transferase.
    IPR020841. PKS_Beta-ketoAc_synthase_dom.
    IPR020843. PKS_ER.
    IPR013968. PKS_KR.
    IPR029063. SAM-dependent_MTases-like.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF00698. Acyl_transf_1. 1 hit.
    PF08240. ADH_N. 1 hit.
    PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    PF00109. ketoacyl-synt. 1 hit.
    PF02801. Ketoacyl-synt_C. 1 hit.
    PF08659. KR. 1 hit.
    PF08242. Methyltransf_12. 1 hit.
    PF00550. PP-binding. 1 hit.
    [Graphical view]
    SMARTiSM00827. PKS_AT. 1 hit.
    SM00829. PKS_ER. 1 hit.
    SM00825. PKS_KS. 1 hit.
    [Graphical view]
    SUPFAMiSSF47336. SSF47336. 1 hit.
    SSF50129. SSF50129. 1 hit.
    SSF52151. SSF52151. 2 hits.
    SSF53335. SSF53335. 1 hit.
    SSF53901. SSF53901. 5 hits.
    SSF55048. SSF55048. 1 hit.
    PROSITEiPS50075. ACP_DOMAIN. 1 hit.
    PS00606. B_KETOACYL_SYNTHASE. 1 hit.
    PS00012. PHOSPHOPANTETHEINE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q55E72-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKNSKIQSP NSSDVAVIGV GFRFPGNSND PESLWNNLLD GFDAITQVPK     50
    ERWATSFREM GLIKNKFGGF LKDSEWKNFD PLFFGIGPKE APFIDPQQRL 100
    LLSIVWESLE DAYIRPDELR GSNTGVFIGV SNNDYTKLGF QDNYSISPYT 150
    MTGSNSSLNS NRISYCFDFR GPSITVDTAC SSSLVSVNLG VQSIQMGECK 200
    IAICGGVNAL FDPSTSVAFS KLGVLSENGR CNSFSDQASG YVRSEGAGVV 250
    VLKSLEQAKL DGDRIYGVIK GVSSNEDGAS NGDKNSLTTP SCEAQSINIS 300
    KAMEKASLSP SDIYYIEAHG TGTPVGDPIE VKALSKIFSN SNNNQLNNFS 350
    TDGNDNDDDD DDNTSPEPLL IGSFKSNIGH LESAAGIASL IKCCLMLKNR 400
    MLVPSINCSN LNPSIPFDQY NISVIREIRQ FPTDKLVNIG INSFGFGGSN 450
    CHLIIQEYNN NFKNNSTICN NNNNNNNNID YLIPISSKTK KSLDKYLILI 500
    KTNSNYHKDI SFDDFVKFQI KSKQYNLSNR MTTIANDWNS FIKGSNEFHN 550
    LIESKDGEGG SSSSNRGIDS ANQINTTTTS TINDIEPLLV FVFCGQGPQW 600
    NGMIKTLYNS ENVFKNTVDH VDSILYKYFG YSILNVLSKI DDNDDSINHP 650
    IVAQPSLFLL QIGLVELFKY WGIYPSISVG HSFGEVSSYY LSGIISLETA 700
    CKIVYVRSSN QNKTMGSGKM LVVSMGFKQW NDQFSAEWSD IEIACYNAPD 750
    SIVVTGNEER LKELSIKLSD ESNQIFNTFL RSPCSFHSSH QEVIKGSMFE 800
    ELSNLQSTGE TEIPLFSTVT GRQVLSGHVT AQHIYDNVRE PVLFQKTIES 850
    ITSYIKSHYP SNQKVIYVEI APHPTLFSLI KKSIPSSNKN SSSVLCPLNR 900
    KENSNNSYKK FVSQLYFNGV NVDFNFQLNS ICDNVNNDHH LNNVKQNSFK 950
    ETTNSLPRYQ WEQDEYWSEP LISRKNRLEG PTTSLLGHRI IYSFPVFQSV 1000
    LDLQSDNYKY LLDHLVNGKP VFPGAGYLDI IIEFFDYQKQ QLNSSDSSNS 1050
    YIINVDKIQF LNPIHLTENK LQTLQSSFEP IVTKKSAFSV NFFIKDTVED 1100
    QSKVKSMSDE TWTNTCKATI SLEQQQPSPS STLTLSKKQD LQILRNRCDI 1150
    SKLDKFELYD KISKNLGLQY NSLFQVVDTI ETGKDCSFAT LSLPEDTLFT 1200
    TILNPCLLDN CFHGLLTLIN EKGSFVVESI SSVSIYLENI GSFNQTSVGN 1250
    VQFYLYTTIS KATSFSSEGT CKLFTKDGSL ILSIGKFIIK STNPKSTKTN 1300
    ETIESPLDET FSIEWQSKDS PIPTPQQIQQ QSPLNSNPSF IRSTILKDIQ 1350
    FEQYCSSIIH KELINHEKYK NQQSFDINSL ENHLNDDQLM ESLSISKEYL 1400
    RFFTRIISII KQYPKILNEK ELKELKEIIE LKYPSEVQLL EFEVIEKVSM 1450
    IIPKLLFEND KQSSMTLFQD NLLTRFYSNS NSTRFYLERV SEMVLESIRP 1500
    IVREKRVFRI LEIGAGTGSL SNVVLTKLNT YLSTLNSNGG SGYNIIIEYT 1550
    FTDISANFII GEIQETMCNL YPNVTFKFSV LDLEKEIINS SDFLMGDYDI 1600
    VLMAYVIHAV SNIKFSIEQL YKLLSPRGWL LCIEPKSNVV FSDLVFGCFN 1650
    QWWNYYDDIR TTHCSLSESQ WNQLLLNQSL NNESSSSSNC YGGFSNVSFI 1700
    GGEKDVDSHS FILHCQKESI SQMKLATTIN NGLSSGSIVI VLNSQQLTNM 1750
    KSYPKVIEYI QEATSLCKTI EIIDSKDVLN STNSVLEKIQ KSLLVFCLLG 1800
    YDLLENNYQE QSFEYVKLLN LISTTASSSN DKKPPKVLLI TKQSERISRS 1850
    FYSRSLIGIS RTSMNEYPNL SITSIDLDTN DYSLQSLLKP IFSNSKFSDN 1900
    EFIFKKGLMF VSRIFKNKQL LESSNAFETD SSNLYCKASS DLSYKYAIKQ 1950
    SMLTENQIEI KVECVGINFK DNLFYKGLLP QEIFRMGDIY NPPYGLECSG 2000
    VITRIGSNVT EYSVGQNVFG FARHSLGSHV VTNKDLVILK PDTISFSEAA 2050
    SIPVVYCTAW YSLFNIGQLS NEESILIHSA TGGVGLASLN LLKMKNQQQQ 2100
    PLTNVYATVG SNEKKKFLID NFNNLFKEDG ENIFSTRDKE YSNQLESKID 2150
    VILNTLSGEF VESNFKSLRS FGRLIDLSAT HVYANQQIGL GNFKFDHLYS 2200
    AVDLERLIDE KPKLLQSILQ RITNSIVNGS LEKIPITIFP STETKDAIEL 2250
    LSKRSHIGKV VVDCTDISKC NPVGDVITNF SMRLPKPNYQ LNLNSTLLIT 2300
    GQSGLSIPLL NWLLSKSGGN VKNVVIISKS TMKWKLQTMI SHFVSGFGIH 2350
    FNYVQVDISN YDALSEAIKQ LPSDLPPITS VFHLAAIYND VPMDQVTMST 2400
    VESVHNPKVL GAVNLHRISV SFGWKLNHFV LFSSITAITG YPDQSIYNSA 2450
    NSILDALSNF RRFMGLPSFS INLGPMKDEG KVSTNKSIKK LFKSRGLPSL 2500
    SLNKLFGLLE VVINNPSNHV IPSQLICSPI DFKTYIESFS TMRPKLLHLQ 2550
    PTISKQQSSI INDSTKASSN ISLQDKITSK VSDLLSIPIS KINFDHPLKH 2600
    YGLDSLLTVQ FKSWIDKEFE KNLFTHIQLA TISINSFLEK VNGLSTNNNN 2650
    NNNSNVKSSP SIVKEEIVTL DKDQQPLLLK EHQHIIISPD IRINKPKRES 2700
    LIRTPILNKF NQITESIITP STPSLSQSDV LKTPPIKSLN NTKNSSLINT 2750
    PPIQSVQQHQ KQQQKVQVIQ QQQQPLSRLS YKSNNNSFVL GIGISVPGEP 2800
    ISQQSLKDSI SNDFSDKAET NEKVKRIFEQ SQIKTRHLVR DYTKPENSIK 2850
    FRHLETITDV NNQFKKVVPD LAQQACLRAL KDWGGDKGDI THIVSVTSTG 2900
    IIIPDVNFKL IDLLGLNKDV ERVSLNLMGC LAGLSSLRTA ASLAKASPRN 2950
    RILVVCTEVC SLHFSNTDGG DQMVASSIFA DGSAAYIIGC NPRIEETPLY 3000
    EVMCSINRSF PNTENAMVWD LEKEGWNLGL DASIPIVIGS GIEAFVDTLL 3050
    DKAKLQTSTA ISAKDCEFLI HTGGKSILMN IENSLGIDPK QTKNTWDVYH 3100
    AYGNMSSASV IFVMDHARKS KSLPTYSISL AFGPGLAFEG CFLKNVV 3147
    Length:3,147
    Mass (Da):352,195
    Last modified:May 24, 2005 - v1
    Checksum:i6B67391AB6596F46
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000005 Genomic DNA. Translation: EAL72032.1.
    RefSeqiXP_645909.1. XM_640817.1.

    Genome annotation databases

    EnsemblProtistsiDDB0234164; DDB0234164; DDB_G0269364.
    GeneIDi8616850.
    KEGGiddi:DDB_G0269364.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000005 Genomic DNA. Translation: EAL72032.1 .
    RefSeqi XP_645909.1. XM_640817.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2H84 X-ray 2.90 A/B 2776-3147 [» ]
    ProteinModelPortali Q55E72.
    SMRi Q55E72. Positions 2785-3147.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDBDRAFT_0190208.

    Proteomic databases

    PRIDEi Q55E72.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0234164 ; DDB0234164 ; DDB_G0269364 .
    GeneIDi 8616850.
    KEGGi ddi:DDB_G0269364.

    Organism-specific databases

    dictyBasei DDB_G0269364. stlA.

    Phylogenomic databases

    eggNOGi COG3424.
    InParanoidi Q55E72.
    OMAi NDDSINH.
    PhylomeDBi Q55E72.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Miscellaneous databases

    EvolutionaryTracei Q55E72.

    Family and domain databases

    Gene3Di 1.10.1200.10. 1 hit.
    3.40.366.10. 2 hits.
    3.40.47.10. 4 hits.
    3.40.50.150. 1 hit.
    3.40.50.720. 2 hits.
    3.90.180.10. 1 hit.
    InterProi IPR001227. Ac_transferase_dom.
    IPR009081. Acyl_carrier_prot-like.
    IPR014043. Acyl_transferase.
    IPR016035. Acyl_Trfase/lysoPLipase.
    IPR013154. ADH_GroES-like.
    IPR012328. Chalcone/stilbene_synth_C.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011032. GroES-like.
    IPR018201. Ketoacyl_synth_AS.
    IPR014031. Ketoacyl_synth_C.
    IPR014030. Ketoacyl_synth_N.
    IPR016036. Malonyl_transacylase_ACP-bd.
    IPR013217. Methyltransf_12.
    IPR016040. NAD(P)-bd_dom.
    IPR020801. PKS_acyl_transferase.
    IPR020841. PKS_Beta-ketoAc_synthase_dom.
    IPR020843. PKS_ER.
    IPR013968. PKS_KR.
    IPR029063. SAM-dependent_MTases-like.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF00698. Acyl_transf_1. 1 hit.
    PF08240. ADH_N. 1 hit.
    PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    PF00109. ketoacyl-synt. 1 hit.
    PF02801. Ketoacyl-synt_C. 1 hit.
    PF08659. KR. 1 hit.
    PF08242. Methyltransf_12. 1 hit.
    PF00550. PP-binding. 1 hit.
    [Graphical view ]
    SMARTi SM00827. PKS_AT. 1 hit.
    SM00829. PKS_ER. 1 hit.
    SM00825. PKS_KS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47336. SSF47336. 1 hit.
    SSF50129. SSF50129. 1 hit.
    SSF52151. SSF52151. 2 hits.
    SSF53335. SSF53335. 1 hit.
    SSF53901. SSF53901. 5 hits.
    SSF55048. SSF55048. 1 hit.
    PROSITEi PS50075. ACP_DOMAIN. 1 hit.
    PS00606. B_KETOACYL_SYNTHASE. 1 hit.
    PS00012. PHOSPHOPANTETHEINE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    2. "Polyketide synthase genes and the natural products potential of Dictyostelium discoideum."
      Zucko J., Skunca N., Curk T., Zupan B., Long P.F., Cullum J., Kessin R.H., Hranueli D.
      Bioinformatics 23:2543-2549(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION.
    3. "Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase."
      Austin M.B., Saito T., Bowman M.E., Haydock S., Kato A., Moore B.S., Kay R.R., Noel J.P.
      Nat. Chem. Biol. 2:494-502(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 2776-3147, FUNCTION, DEVELOPMENTAL STAGE, SUBUNIT.

    Entry informationi

    Entry nameiPKS1_DICDI
    AccessioniPrimary (citable) accession number: Q55E72
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Miscellaneous

    In reference to their hybrid nature and to their discovery in D.discoideum, authors term these type I FAS-type III PKS fusion enzymes 'steely'.1 Publication
    Encoded by one of the numerous copies of polyketide synthase genes localized in chromosome 1.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3