Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tryptophan--tRNA ligase, cytoplasmic

Gene

trpS

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligase, cytoplasmic (EC:6.1.1.2)
Alternative name(s):
Tryptophanyl-tRNA synthetase
Short name:
TrpRS
Gene namesi
Name:trpS
ORF Names:DDB_G0269454
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269454 trpS

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003277921 – 400Tryptophan--tRNA ligase, cytoplasmicAdd BLAST400

Proteomic databases

PaxDbiQ55DZ8

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0231245

Structurei

3D structure databases

ProteinModelPortaliQ55DZ8
SMRiQ55DZ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi95 – 104"HIGH" region10
Motifi281 – 285"KMSKS" region5

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2145 Eukaryota
COG0180 LUCA
InParanoidiQ55DZ8
KOiK01867
OMAiADILHPQ
PhylomeDBiQ55DZ8

Family and domain databases

CDDicd00806 TrpRS_core, 1 hit
Gene3Di3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR002305 aa-tRNA-synth_Ic
IPR014729 Rossmann-like_a/b/a_fold
IPR002306 Trp-tRNA-ligase
PfamiView protein in Pfam
PF00579 tRNA-synt_1b, 1 hit
PRINTSiPR01039 TRNASYNTHTRP
TIGRFAMsiTIGR00233 trpS, 1 hit

Sequencei

Sequence statusi: Complete.

Q55DZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTETTPTTNE TKEQVITPWE VEAAPGGSVD YMKLVDQFGS TVISEELIAR
60 70 80 90 100
FEKVTGKRAH HFLRRGIFFS HRDLKEILDH HESGKKWFLY TGRGPSSGSL
110 120 130 140 150
HFGHLLPFTF TKYLQDAFNV PLVVQMTNDE KFLWKDMTLE ESIKFTHNNV
160 170 180 190 200
KDIIALGFDI QKTFIFSNLE YIHHLYPNVL KIARCVNLNQ IQNIFGFKES
210 220 230 240 250
DAIGKFTFPP VQAAPCFPDS FPHIFPLNDP EIKNIRCLIP CAIDQDPYFR
260 270 280 290 300
MTRDIAHRIG HQKPALIHSK FFPALQGHNT KMSASDTNSA VYLSDTPDQV
310 320 330 340 350
KDKIKKHAFS GGGATKEEQE KNGADLSVDI TYEYLTFMLE DDEQLKDIAH
360 370 380 390 400
RYSTGKMMTG EIKQILIDLM NKIIIRHKEA RAKITDEVLS TFMSIRKLNF
Length:400
Mass (Da):45,850
Last modified:May 24, 2005 - v1
Checksum:i38FC775E37AE342C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000005 Genomic DNA Translation: EAL72077.1
RefSeqiXP_645983.1, XM_640891.1

Genome annotation databases

EnsemblProtistsiEAL72077; EAL72077; DDB_G0269454
GeneIDi8616928
KEGGiddi:DDB_G0269454

Similar proteinsi

Entry informationi

Entry nameiSYWC_DICDI
AccessioniPrimary (citable) accession number: Q55DZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health