Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q55DZ8 (SYWC_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tryptophan--tRNA ligase, cytoplasmic

EC=6.1.1.2
Alternative name(s):
Tryptophanyl-tRNA synthetase
Short name=TrpRS
Gene names
Name:trpS
ORF Names:DDB_G0269454
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Tryptophan--tRNA ligase, cytoplasmic
PRO_0000327792

Regions

Motif95 – 10410"HIGH" region
Motif281 – 2855"KMSKS" region

Sequences

Sequence LengthMass (Da)Tools
Q55DZ8 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 38FC775E37AE342C

FASTA40045,850
        10         20         30         40         50         60 
MTETTPTTNE TKEQVITPWE VEAAPGGSVD YMKLVDQFGS TVISEELIAR FEKVTGKRAH 

        70         80         90        100        110        120 
HFLRRGIFFS HRDLKEILDH HESGKKWFLY TGRGPSSGSL HFGHLLPFTF TKYLQDAFNV 

       130        140        150        160        170        180 
PLVVQMTNDE KFLWKDMTLE ESIKFTHNNV KDIIALGFDI QKTFIFSNLE YIHHLYPNVL 

       190        200        210        220        230        240 
KIARCVNLNQ IQNIFGFKES DAIGKFTFPP VQAAPCFPDS FPHIFPLNDP EIKNIRCLIP 

       250        260        270        280        290        300 
CAIDQDPYFR MTRDIAHRIG HQKPALIHSK FFPALQGHNT KMSASDTNSA VYLSDTPDQV 

       310        320        330        340        350        360 
KDKIKKHAFS GGGATKEEQE KNGADLSVDI TYEYLTFMLE DDEQLKDIAH RYSTGKMMTG 

       370        380        390        400 
EIKQILIDLM NKIIIRHKEA RAKITDEVLS TFMSIRKLNF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000005 Genomic DNA. Translation: EAL72077.1.

3D structure databases

ProteinModelPortalQ55DZ8.
SMRQ55DZ8. Positions 28-400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231245.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231245; DDB0231245; DDB_G0269454.
KEGGddi:DDB_G0269454.

Organism-specific databases

dictyBaseDDB_G0269454. trpS.

Phylogenomic databases

eggNOGCOG0180.
KOK01867.
OMAKPETAIY.
PhylomeDBQ55DZ8.
ProtClustDBCLSZ2729284.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
InterProIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
[Graphical view]
PANTHERPTHR10055. PTHR10055. 1 hit.
PfamPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSPR01039. TRNASYNTHTRP.
TIGRFAMsTIGR00233. trpS. 1 hit.
ProtoNetSearch...

Other

PROQ55DZ8.

Entry information

Entry nameSYWC_DICDI
AccessionPrimary (citable) accession number: Q55DZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries