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Protein

Frizzled and smoothened-like protein D

Gene

fslD

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Keywordsi

Molecular functionReceptor

Names & Taxonomyi

Protein namesi
Recommended name:
Frizzled and smoothened-like protein D
Gene namesi
Name:fslD
ORF Names:DDB_G0269528
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269528. fslD.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 257ExtracellularSequence analysisAdd BLAST236
Transmembranei258 – 278Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini279 – 287CytoplasmicSequence analysis9
Transmembranei288 – 308Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini309 – 335ExtracellularSequence analysisAdd BLAST27
Transmembranei336 – 356Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini357 – 368CytoplasmicSequence analysisAdd BLAST12
Transmembranei369 – 389Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini390 – 410ExtracellularSequence analysisAdd BLAST21
Transmembranei411 – 431Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini432 – 454CytoplasmicSequence analysisAdd BLAST23
Transmembranei455 – 475Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini476 – 513ExtracellularSequence analysisAdd BLAST38
Transmembranei514 – 534Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini535 – 634CytoplasmicSequence analysisAdd BLAST100

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000037136622 – 634Frizzled and smoothened-like protein DAdd BLAST613

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi126N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi168N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi215N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi243N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi254N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ55DT7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 178FZAdd BLAST145

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi63 – 69Poly-Gly7
Compositional biasi566 – 569Poly-Gly4
Compositional biasi576 – 583Poly-Ser8
Compositional biasi587 – 590Poly-Asn4
Compositional biasi615 – 623Poly-Asn9

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ55DT7.
PhylomeDBiQ55DT7.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q55DT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINKFKFYLI FLKLILILVN CQNSLNDYGF GIVDESSICT SYIGDELCKN
60 70 80 90 100
RLSNSESIYT TPGGGGGGGI DKLSQISTLP ILQKGFQSLT FSQGICKDLN
110 120 130 140 150
FIEFGMCDSA LSPCIETTPK ITPGYNISLP QRVCKSVCER MLIGCPQLAI
160 170 180 190 200
QIDCSISFLF PKIGTFYNLT KYGYTANGGM YMVPCIDTEI NYEKNKVQEN
210 220 230 240 250
VGFLESCPYP LLLKNSTDPQ YAEKRGYTYL TPTNCVLPCP IPNYTKRQMD
260 270 280 290 300
SVINMSKAMS SISFVLSLFN VITFGLLIKK KSKYNVCIAL MAIGSSFIYL
310 320 330 340 350
SDIINYGVGI EKQLCPEPGR VATQRVDSLC GFTGSIFHIG ITLCVLWSMT
360 370 380 390 400
MGIVLYSKIK QFKLPNFRYF LIGNLSFTVV TLIILASAKK FQGGNGFLEC
410 420 430 440 450
WMRDRWYVVA IFWIPCGIAL LLGVLSICGV IFEIYKISKN VSLKDSKVVI
460 470 480 490 500
RELKPFVLVV TVSASLIYLF VFYFDSESKY DFYKKGVEDY ILCLLTSENP
510 520 530 540 550
LDECYTVGPN FNSYFMFYFL IRFFGILFFG IFGTSEIARN AWTESFFVTK
560 570 580 590 600
IKSKISITTV SSSTRGGGGD TSGIKSSSSS SNSGVCNNNN STRKNYGDDF
610 620 630
NSKNLSQPDN TIITNNNNND NNNKMEIELD SIDI
Length:634
Mass (Da):70,779
Last modified:May 24, 2005 - v1
Checksum:i831C6B576661949A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000005 Genomic DNA. Translation: EAL72114.1.
RefSeqiXP_646044.1. XM_640952.1.

Genome annotation databases

EnsemblProtistsiEAL72114; EAL72114; DDB_G0269528.
GeneIDi8616991.
KEGGiddi:DDB_G0269528.

Entry informationi

Entry nameiFSLD_DICDI
AccessioniPrimary (citable) accession number: Q55DT7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 24, 2005
Last modified: May 10, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  3. SIMILARITY comments
    Index of protein domains and families