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Q55DQ4 (PGTA_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Geranylgeranyl transferase type-2 subunit alpha

EC=2.5.1.60
Alternative name(s):
GGTase-II-alpha
Geranylgeranyl transferase type II subunit alpha
PGGT
Type II protein geranyl-geranyltransferase subunit alpha
Gene names
Name:rabggta
ORF Names:DDB_G0269570
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to proteins with a C-terminal sequence motif -XCC or -XCXC, where both cysteines may become modified By similarity.

Catalytic activity

Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.

Subunit structure

Heterodimer of an alpha and a beta subunit By similarity.

Sequence similarities

Belongs to the protein prenyltransferase subunit alpha family.

Contains 5 PFTA repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Geranylgeranyl transferase type-2 subunit alpha
PRO_0000331287

Regions

Repeat49 – 8234PFTA 1
Repeat93 – 12634PFTA 2
Repeat129 – 16234PFTA 3
Repeat164 – 19734PFTA 4
Repeat206 – 23934PFTA 5
Coiled coil12 – 4332 Potential

Sequences

Sequence LengthMass (Da)Tools
Q55DQ4 [UniParc].

Last modified March 18, 2008. Version 2.
Checksum: F6640179FFC4DC41

FASTA31137,779
        10         20         30         40         50         60 
MHGVLKVRTS EEKAKAQRLK ELEKIESYNK LVKSFEELRE KQNGRYDEIS LSVSKLVLIE 

        70         80         90        100        110        120 
NPEFYTIWNY RRLAILQFTE TKENSELQVI YQNEMKFLEE CIQRFTKSYW IWFHRQWIAL 

       130        140        150        160        170        180 
RMDNCDWERE MKLCTKLLNF DLRNFHCWGH RRFILKHSNI KLEDELKYTT EKVEQNFSNY 

       190        200        210        220        230        240 
SAWHQRSSIL PKIYKEPEQL LEKILEEFEL VRNAVYTEPK DSSSWIYHKW LVATIKSIPN 

       250        260        270        280        290        300 
SNYIEVLKNE LTQIYDLIEL EPDCKWPIYT TLLLKIEIGG FEKQELLDII SQLIKLDPDH 

       310 
KNYYKSLETK I 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000005 Genomic DNA. Translation: EAL72135.2.
RefSeqXP_646077.2. XM_640985.2.

3D structure databases

ProteinModelPortalQ55DQ4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0190367.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0233950; DDB0233950; DDB_G0269570.
GeneID8617027.
KEGGddi:DDB_G0269570.

Organism-specific databases

dictyBaseDDB_G0269570. rabggta.

Phylogenomic databases

eggNOGCOG5536.
OMAAWNYRRY.
PhylomeDBQ55DQ4.

Family and domain databases

InterProIPR002088. Prenyl_trans_a.
[Graphical view]
PfamPF01239. PPTA. 4 hits.
[Graphical view]
PROSITEPS51147. PFTA. 5 hits.
[Graphical view]
ProtoNetSearch...

Other

PROQ55DQ4.

Entry information

Entry namePGTA_DICDI
AccessionPrimary (citable) accession number: Q55DQ4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 18, 2008
Last modified: July 9, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase