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Q55CT5

- SEC31_DICDI

UniProt

Q55CT5 - SEC31_DICDI

Protein

Protein transport protein SEC31

Gene

sec31

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules By similarity.By similarity

    GO - Biological processi

    1. ER to Golgi vesicle-mediated transport Source: dictyBase
    2. intracellular protein transport Source: dictyBase
    3. RNA splicing Source: InterPro

    Keywords - Biological processi

    ER-Golgi transport, Protein transport, Transport

    Enzyme and pathway databases

    ReactomeiREACT_210982. COPII (Coat Protein 2) Mediated Vesicle Transport.
    REACT_218739. XBP1(S) activates chaperone genes.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein transport protein SEC31
    Gene namesi
    Name:sec31
    ORF Names:DDB_G0270992
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0270992. sec31.

    Subcellular locationi

    GO - Cellular componenti

    1. COPII vesicle coat Source: dictyBase
    2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    3. spliceosomal complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasmic vesicle, Endoplasmic reticulum, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13551355Protein transport protein SEC31PRO_0000328076Add
    BLAST

    Proteomic databases

    PRIDEiQ55CT5.

    Interactioni

    Subunit structurei

    The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1A or sar1B. sec13 and sec31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with sec13 By similarity.By similarity

    Protein-protein interaction databases

    STRINGi44689.DDBDRAFT_0216723.

    Structurei

    3D structure databases

    ProteinModelPortaliQ55CT5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati5 – 4844WD 1Add
    BLAST
    Repeati65 – 10945WD 2Add
    BLAST
    Repeati127 – 16741WD 3Add
    BLAST
    Repeati175 – 21541WD 4Add
    BLAST
    Repeati220 – 26344WD 5Add
    BLAST
    Repeati267 – 30741WD 6Add
    BLAST
    Repeati334 – 37441WD 7Add
    BLAST
    Repeati412 – 46352WD 8; interaction with sec13PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi437 – 4437Poly-Ser
    Compositional biasi449 – 4579Poly-Gln
    Compositional biasi570 – 5745Poly-Thr
    Compositional biasi612 – 6176Poly-Ser
    Compositional biasi622 – 6265Poly-Thr
    Compositional biasi774 – 7829Poly-Gln
    Compositional biasi902 – 9098Poly-Gln
    Compositional biasi943 – 95311Poly-GlnAdd
    BLAST
    Compositional biasi969 – 98012Poly-GlnAdd
    BLAST
    Compositional biasi984 – 1188205Met/Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the WD repeat SEC31 family.Curated
    Contains 8 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    eggNOGiNOG248389.
    KOiK14005.
    OMAiMMNQGPP.
    PhylomeDBiQ55CT5.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR004098. Prp18.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF02840. Prp18. 1 hit.
    PF00400. WD40. 3 hits.
    [Graphical view]
    SMARTiSM00320. WD40. 5 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    PROSITEiPS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 3 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q55CT5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKLKEISRQ STTSWSPIAQ YPDYMAVGTV TGTIGADFDT SSKLEIYSLD     50
    ITNESKQMTL KGSTSSSTRF NKVVWGQASS NFQNGIIAGA MDNGTINLWD 100
    PTKILASDAT DGGGSDDQSS LIGVGQRHSG PVQSIDFNVQ NPNLLASGGS 150
    DSEVFIWDLS DPTQPSALNP GSKSQQSSDI TCVAWNKKVA HILGSASYNG 200
    YIVIWDLKSK KTLMTINDRN RKCKYRSIVW HPSEATQIVA ASEDDDHPVI 250
    QAWDLRNTTS PVKSMEGHKK GVWGLSWCPS DNALLLSTGK DNKTFCWNFD 300
    RQEILCEIND NNSRNNINNN SNNSNSDNNN GNTDPNAWNF EVQWSPRVPA 350
    LLSTSSYVGK VNVYSLQDVN EKSTSGSSAG QLNALGIQEQ TSQITPTIKH 400
    TPNWLLRPCG AAFGFGGKIA VFGRNKKVTA AANGATSPSS SSSPASSVQQ 450
    SQLQQQQRVI HISHVTTEVD IVKSSEQLEN VIHTGQYEQY CQEKIDQSTS 500
    DEEKSIWGFL KVKFAKDDRL KILDYLGYDI ETIKKELKQF LGTLPELPIE 550
    SGFNELPIEN VDDQSKPEPT TTTTNETVHL EPVVDENNNV VDADSFFDTA 600
    ASDANKEQQD DSSSSPSTKS PTTTTTPIEF PGDEKEQMIT KALLVGDHNS 650
    AVECCLRLGR YSDALILAHA AGQELWKKTQ EAYFEIVRSP FGRVVSCIVK 700
    RDFQLLVKSA DLKDWKASLA ILCTYAPPTD FKILSGILGD RLDKEASDLK 750
    SAILCYICAG DIDKTVDIWS RVSQQHQQQQ RQSLTSSGNS ITVLEQESNK 800
    DLQNLIEKVS IFRSACNGNS NNNTLNQVLS MKYAKYAEIL ASQGNLSASL 850
    RYLAPITNSQ CKQEYGVLFD RVYRATSNHQ GIPQPPFPFQ LVDVYSSNQP 900
    IQQQQQQQQN KAQQVGHQHQ HQHQHQNQHQ HQHQHQHQHQ PPQQQQQQQQ 950
    QQQMGRQNTF NQPPQPMGQH QHQQQQQQQQ PPIMMNQSPM QNNNNNRIPM 1000
    MNQPPMMNQP PMMNQPPMMN QPPQMMNQPP QMMNQPPPQM MNQPPPQMMN 1050
    NNQPPIMMRP MQPSGPSPMN PPPTMNNTQP PPMMNTMGGP SSVNNSQPPI 1100
    IPMNGNPLPM NPMSPMMSDK SNQPPMNPMM NPMNPMNPMM NPIQPTAPPP 1150
    MNPMIPQGGS PMINHPPPPM NPMINNGPVS TPPMNPMMNQ VVPQNISPPQ 1200
    MPTRSPVLEN KSSSPSSESF TSPAPKPNVH NKTPSIITGQ LGVTTPSEGP 1250
    SNEDTERFVE KLQRSIQELN GRTDSKVWED ANKRCQGLIN KVSKKDISAE 1300
    AFKALDAILA SIVEKDFKKA SDTYIQITST PLWGEVGSQS MVGLKRLIDL 1350
    GLKSH 1355
    Length:1,355
    Mass (Da):150,127
    Last modified:May 24, 2005 - v1
    Checksum:i885303FDEEB8959F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000005 Genomic DNA. Translation: EAL72846.1.
    RefSeqiXP_646396.1. XM_641304.1.

    Genome annotation databases

    EnsemblProtistsiDDB0235185; DDB0235185; DDB_G0270992.
    GeneIDi8617351.
    KEGGiddi:DDB_G0270992.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000005 Genomic DNA. Translation: EAL72846.1 .
    RefSeqi XP_646396.1. XM_641304.1.

    3D structure databases

    ProteinModelPortali Q55CT5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDBDRAFT_0216723.

    Proteomic databases

    PRIDEi Q55CT5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0235185 ; DDB0235185 ; DDB_G0270992 .
    GeneIDi 8617351.
    KEGGi ddi:DDB_G0270992.

    Organism-specific databases

    dictyBasei DDB_G0270992. sec31.

    Phylogenomic databases

    eggNOGi NOG248389.
    KOi K14005.
    OMAi MMNQGPP.
    PhylomeDBi Q55CT5.

    Enzyme and pathway databases

    Reactomei REACT_210982. COPII (Coat Protein 2) Mediated Vesicle Transport.
    REACT_218739. XBP1(S) activates chaperone genes.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR004098. Prp18.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF02840. Prp18. 1 hit.
    PF00400. WD40. 3 hits.
    [Graphical view ]
    SMARTi SM00320. WD40. 5 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    PROSITEi PS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 3 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiSEC31_DICDI
    AccessioniPrimary (citable) accession number: Q55CT5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3