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Q55CT5

- SEC31_DICDI

UniProt

Q55CT5 - SEC31_DICDI

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Protein

Protein transport protein SEC31

Gene

sec31

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).By similarity

GO - Biological processi

  1. ER to Golgi vesicle-mediated transport Source: dictyBase
  2. intracellular protein transport Source: dictyBase
  3. RNA splicing Source: InterPro
Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein SEC31
Gene namesi
Name:sec31
ORF Names:DDB_G0270992
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0270992. sec31.

Subcellular locationi

GO - Cellular componenti

  1. COPII vesicle coat Source: dictyBase
  2. endoplasmic reticulum Source: UniProtKB-KW
  3. spliceosomal complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasmic vesicle, Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13551355Protein transport protein SEC31PRO_0000328076Add
BLAST

Proteomic databases

PRIDEiQ55CT5.

Interactioni

Subunit structurei

The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1A or sar1B. sec13 and sec31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with sec13 (By similarity).By similarity

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0216723.

Structurei

3D structure databases

ProteinModelPortaliQ55CT5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati5 – 4844WD 1Add
BLAST
Repeati65 – 10945WD 2Add
BLAST
Repeati127 – 16741WD 3Add
BLAST
Repeati175 – 21541WD 4Add
BLAST
Repeati220 – 26344WD 5Add
BLAST
Repeati267 – 30741WD 6Add
BLAST
Repeati334 – 37441WD 7Add
BLAST
Repeati412 – 46352WD 8; interaction with sec13PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi437 – 4437Poly-Ser
Compositional biasi449 – 4579Poly-Gln
Compositional biasi570 – 5745Poly-Thr
Compositional biasi612 – 6176Poly-Ser
Compositional biasi622 – 6265Poly-Thr
Compositional biasi774 – 7829Poly-Gln
Compositional biasi902 – 9098Poly-Gln
Compositional biasi943 – 95311Poly-GlnAdd
BLAST
Compositional biasi969 – 98012Poly-GlnAdd
BLAST
Compositional biasi984 – 1188205Met/Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the WD repeat SEC31 family.Curated
Contains 8 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiNOG248389.
InParanoidiQ55CT5.
KOiK14005.
OMAiMMNQGPP.
PhylomeDBiQ55CT5.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR004098. Prp18.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF02840. Prp18. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55CT5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKLKEISRQ STTSWSPIAQ YPDYMAVGTV TGTIGADFDT SSKLEIYSLD
60 70 80 90 100
ITNESKQMTL KGSTSSSTRF NKVVWGQASS NFQNGIIAGA MDNGTINLWD
110 120 130 140 150
PTKILASDAT DGGGSDDQSS LIGVGQRHSG PVQSIDFNVQ NPNLLASGGS
160 170 180 190 200
DSEVFIWDLS DPTQPSALNP GSKSQQSSDI TCVAWNKKVA HILGSASYNG
210 220 230 240 250
YIVIWDLKSK KTLMTINDRN RKCKYRSIVW HPSEATQIVA ASEDDDHPVI
260 270 280 290 300
QAWDLRNTTS PVKSMEGHKK GVWGLSWCPS DNALLLSTGK DNKTFCWNFD
310 320 330 340 350
RQEILCEIND NNSRNNINNN SNNSNSDNNN GNTDPNAWNF EVQWSPRVPA
360 370 380 390 400
LLSTSSYVGK VNVYSLQDVN EKSTSGSSAG QLNALGIQEQ TSQITPTIKH
410 420 430 440 450
TPNWLLRPCG AAFGFGGKIA VFGRNKKVTA AANGATSPSS SSSPASSVQQ
460 470 480 490 500
SQLQQQQRVI HISHVTTEVD IVKSSEQLEN VIHTGQYEQY CQEKIDQSTS
510 520 530 540 550
DEEKSIWGFL KVKFAKDDRL KILDYLGYDI ETIKKELKQF LGTLPELPIE
560 570 580 590 600
SGFNELPIEN VDDQSKPEPT TTTTNETVHL EPVVDENNNV VDADSFFDTA
610 620 630 640 650
ASDANKEQQD DSSSSPSTKS PTTTTTPIEF PGDEKEQMIT KALLVGDHNS
660 670 680 690 700
AVECCLRLGR YSDALILAHA AGQELWKKTQ EAYFEIVRSP FGRVVSCIVK
710 720 730 740 750
RDFQLLVKSA DLKDWKASLA ILCTYAPPTD FKILSGILGD RLDKEASDLK
760 770 780 790 800
SAILCYICAG DIDKTVDIWS RVSQQHQQQQ RQSLTSSGNS ITVLEQESNK
810 820 830 840 850
DLQNLIEKVS IFRSACNGNS NNNTLNQVLS MKYAKYAEIL ASQGNLSASL
860 870 880 890 900
RYLAPITNSQ CKQEYGVLFD RVYRATSNHQ GIPQPPFPFQ LVDVYSSNQP
910 920 930 940 950
IQQQQQQQQN KAQQVGHQHQ HQHQHQNQHQ HQHQHQHQHQ PPQQQQQQQQ
960 970 980 990 1000
QQQMGRQNTF NQPPQPMGQH QHQQQQQQQQ PPIMMNQSPM QNNNNNRIPM
1010 1020 1030 1040 1050
MNQPPMMNQP PMMNQPPMMN QPPQMMNQPP QMMNQPPPQM MNQPPPQMMN
1060 1070 1080 1090 1100
NNQPPIMMRP MQPSGPSPMN PPPTMNNTQP PPMMNTMGGP SSVNNSQPPI
1110 1120 1130 1140 1150
IPMNGNPLPM NPMSPMMSDK SNQPPMNPMM NPMNPMNPMM NPIQPTAPPP
1160 1170 1180 1190 1200
MNPMIPQGGS PMINHPPPPM NPMINNGPVS TPPMNPMMNQ VVPQNISPPQ
1210 1220 1230 1240 1250
MPTRSPVLEN KSSSPSSESF TSPAPKPNVH NKTPSIITGQ LGVTTPSEGP
1260 1270 1280 1290 1300
SNEDTERFVE KLQRSIQELN GRTDSKVWED ANKRCQGLIN KVSKKDISAE
1310 1320 1330 1340 1350
AFKALDAILA SIVEKDFKKA SDTYIQITST PLWGEVGSQS MVGLKRLIDL

GLKSH
Length:1,355
Mass (Da):150,127
Last modified:May 24, 2005 - v1
Checksum:i885303FDEEB8959F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000005 Genomic DNA. Translation: EAL72846.1.
RefSeqiXP_646396.1. XM_641304.1.

Genome annotation databases

EnsemblProtistsiDDB0235185; DDB0235185; DDB_G0270992.
GeneIDi8617351.
KEGGiddi:DDB_G0270992.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000005 Genomic DNA. Translation: EAL72846.1 .
RefSeqi XP_646396.1. XM_641304.1.

3D structure databases

ProteinModelPortali Q55CT5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDBDRAFT_0216723.

Proteomic databases

PRIDEi Q55CT5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0235185 ; DDB0235185 ; DDB_G0270992 .
GeneIDi 8617351.
KEGGi ddi:DDB_G0270992.

Organism-specific databases

dictyBasei DDB_G0270992. sec31.

Phylogenomic databases

eggNOGi NOG248389.
InParanoidi Q55CT5.
KOi K14005.
OMAi MMNQGPP.
PhylomeDBi Q55CT5.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR004098. Prp18.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF02840. Prp18. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view ]
SMARTi SM00320. WD40. 5 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiSEC31_DICDI
AccessioniPrimary (citable) accession number: Q55CT5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: November 26, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3