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Q55C91 (ALN2_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable allantoinase 2

EC=3.5.2.5
Gene names
Name:allB2
ORF Names:DDB_G0270162
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-allantoin + H2O = allantoate.

Cofactor

Binds 2 zinc ions per subunit By similarity.

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.

Subunit structure

Homotetramer By similarity.

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity.

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 510510Probable allantoinase 2
PRO_0000330751

Sites

Metal binding971Zinc 1 By similarity
Metal binding991Zinc 1 By similarity
Metal binding1851Zinc 1; via carbamate group By similarity
Metal binding1851Zinc 2; via carbamate group By similarity
Metal binding2281Zinc 2 By similarity
Metal binding2871Zinc 2 By similarity
Metal binding3601Zinc 1 By similarity

Amino acid modifications

Modified residue1851N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55C91 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: AEA0E212B455B617

FASTA51057,323
        10         20         30         40         50         60 
MEIWKVIFSI WFLLFQNFVL SAKNDDNKLK VIRGRNVIYN GNVIPLSILI RNGKTIGIKD 

        70         80         90        100        110        120 
YSFNPKKLNE NYEILYDDRE CNNNEDFIIM GGLVDSHVHV NEPGRTEWEG FESATSAAAA 

       130        140        150        160        170        180 
GGVTTIVDMP LNSSPVTTSF KNLLDKIESM KGKLRVDVGL LGGIVPGNSK EIKKMVLQGG 

       190        200        210        220        230        240 
VLGFKSFLLP SGIDEFPPVN ENDIQEAMNE MKLLKCQYNN SDVIMMFHAE VEEPIKEATV 

       250        260        270        280        290        300 
RLKNENADPK LYKTYLDSRP KISENQAISK LIDITRQNQI VSTHIVHLSS SESIEQIREA 

       310        320        330        340        350        360 
MDQGVPISAE TTYNYLHLTS ESVPYGNTLF KSAPPVREHE NKELLWNAII NGTIKLIVSD 

       370        380        390        400        410        420 
HSPCTINLKQ LKEDNQSIGD FLKAWGGISS LELGLPIIWT ECKNRGIPIT QLSEWLSNGP 

       430        440        450        460        470        480 
SKLVGLNDRK GSIEIGRDAD FVIFNPNESF IVNEKKLFLK NKFSAYNGEK LFGVVYETIL 

       490        500        510 
RGNSIFKKGD NKIKKIIGQR LIKSNLINKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000005 Genomic DNA. Translation: EAL72431.1.

3D structure databases

ProteinModelPortalQ55C91.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231351.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231351; DDB0231351; DDB_G0270162.
KEGGddi:DDB_G0270162.

Organism-specific databases

dictyBaseDDB_G0270162. allB2.

Phylogenomic databases

eggNOGCOG0044.
KOK01466.
OMAHAGSIDH.
PhylomeDBQ55C91.
ProtClustDBCLSZ2430485.

Enzyme and pathway databases

UniPathwayUPA00395; UER00653.

Family and domain databases

InterProIPR017593. Allantoinase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 1 hit.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALN2_DICDI
AccessionPrimary (citable) accession number: Q55C91
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase