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Q55C57 (GLKA_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase glkA

EC=2.7.11.26
Alternative name(s):
Glycogen synthase kinase-like kinase A
Gene names
Name:glkA
ORF Names:DDB_G0270218
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length473 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + [tau protein] = ADP + [tau protein] phosphate.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 473473Probable serine/threonine-protein kinase glkA
PRO_0000358885

Regions

Domain91 – 366276Protein kinase
Nucleotide binding97 – 1059ATP By similarity
Compositional bias16 – 4025Poly-Asn
Compositional bias45 – 6016Poly-Asn
Compositional bias64 – 696Poly-Ser
Compositional bias397 – 4026Poly-Ser
Compositional bias412 – 4154Poly-Ser
Compositional bias451 – 4555Poly-Ser

Sites

Active site2081Proton acceptor By similarity
Binding site1191ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55C57 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 72E4295165642D0D

FASTA47352,554
        10         20         30         40         50         60 
MTIPTDNNSS NNKGYNDNNN NNNNNNNNNN NNNNNNNNNN KEHPNINNNN NNNNNNNNNN 

        70         80         90        100        110        120 
IKESSSSNSN HSSSQSSSTA TVNSNPKVYP YEIIKQVGQG TFGKVYEAKN QDNKRVAIKK 

       130        140        150        160        170        180 
VEKSNHFISR EYDILKIVAH PNCLRILDMF YTAEDNKKMQ NLVFDFIPYT LASLLKKRQL 

       190        200        210        220        230        240 
SINFIKVLFY QLCQAIKHIH SKAICHRDIT PNNILLSSKG ELTLADFGSA KILESNHTSM 

       250        260        270        280        290        300 
SYICSRYYRA PELLVGCSNY TTKIDIWSIG CILAEMLIGK PLFPGTNSND QLGRIIEVLG 

       310        320        330        340        350        360 
SPTKDDMEAM KPSKPYHLQL PNINPKFFES LHNVEDKTVV DLLSKIFIFD PVKRASIDEI 

       370        380        390        400        410        420 
IAHPFLRDVN INSLELFDEM KCFSVSGNGK SSLTTNSTSS SSTTANMTSL ASSSSNNKTT 

       430        440        450        460        470 
CSETYLSRLP TSAITSSSNL KSIDNSNNGK SSSSSNNIPS LNNSNNGVIT NTI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000005 Genomic DNA. Translation: EAL72459.1.
RefSeqXP_646624.1. XM_641532.1.

3D structure databases

ProteinModelPortalQ55C57.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0216280.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0216280; DDB0216280; DDB_G0270218.
GeneID8617596.
KEGGddi:DDB_G0270218.

Organism-specific databases

dictyBaseDDB_G0270218. glkA.

Phylogenomic databases

eggNOGCOG0515.
PhylomeDBQ55C57.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLKA_DICDI
AccessionPrimary (citable) accession number: Q55C57
Entry history
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 24, 2005
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase