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Q55988 (K6PF2_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase 2

EC=2.7.1.11
Alternative name(s):
Phosphofructokinase 2
Phosphohexokinase 2
Gene names
Name:pfkA2
Synonyms:pfkA
Ordered Locus Names:sll0745
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3843846-phosphofructokinase 2 HAMAP-Rule MF_00339
PRO_0000111999

Regions

Nucleotide binding23 – 275ATP By similarity
Nucleotide binding173 – 1775ATP By similarity
Nucleotide binding190 – 20617ATP By similarity

Sites

Active site1461Proton acceptor By similarity
Metal binding2041Magnesium; via carbonyl oxygen By similarity
Binding site1811Substrate By similarity
Binding site2911Substrate By similarity
Binding site2971Substrate By similarity
Binding site3001Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55988 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 03034C863DBD9133

FASTA38441,759
        10         20         30         40         50         60 
MGTKRIGILT SGGDCPGLNA VIRAVVKASA LKGWEVYGIP YGTDGFVEVA HGKYQAEDLL 

        70         80         90        100        110        120 
LTKHGYALPG MLKGLDVLQF LSGSVLGSLS KGHPEQPAIA EAILKGYAIL DLEALIVIGG 

       130        140        150        160        170        180 
DGSLDIIYDL AQKGNWHIIA IPKTIDNDVP FTDLAVGFST AVDIVTQALY DLTFTAASHE 

       190        200        210        220        230        240 
RIIIVQVMGR DAGHLTLHAG IAGGADIILI PEITPCLTSE IIRNCCYQLM NLRKSGRHFA 

       250        260        270        280        290        300 
LIVISEGVHD QNNKKNKHIA DYLAEEISET SQHLCDIKDP AFCDLISLDI RATTLGHLQR 

       310        320        330        340        350        360 
SGTPLSFDRL LATVFGIRAV ELIEQEIYDQ VVIWRSGKVE HADLKPIISI IKECHQENRC 

       370        380 
PFPVDRDGFM VKTAKSLGIY LGED 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10770.1.
PIRS77078.
RefSeqNP_442699.1. NC_000911.1.
YP_005652760.1. NC_017277.1.
YP_007452575.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55988.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.sll0745.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10770; BAA10770; BAA10770.
GeneID12254954.
14618257.
952855.
KEGGsyn:sll0745.
syy:SYNGTS_2807.
syz:MYO_128330.
PATRIC23843144. VBISynSp132158_3110.

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000248869.
KOK00850.
OMAIVQVMGR.
OrthoDBEOG644ZRM.
PhylomeDBQ55988.
ProtClustDBPRK03202.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameK6PF2_SYNY3
AccessionPrimary (citable) accession number: Q55988
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways