Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q558Z0

- SYRC_DICDI

UniProt

Q558Z0 - SYRC_DICDI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable arginine--tRNA ligase, cytoplasmic

Gene

argS1

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.By similarity

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_221378. Mitochondrial tRNA aminoacylation.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable arginine--tRNA ligase, cytoplasmic (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS1
Synonyms:argS
ORF Names:DDB_G0272867
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0272867. argS1.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. phagocytic vesicle Source: dictyBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 589589Probable arginine--tRNA ligase, cytoplasmicPRO_0000327521Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi44689.DDB_0231324.

Structurei

3D structure databases

ProteinModelPortaliQ558Z0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi121 – 13212"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
InParanoidiQ558Z0.
KOiK01887.
OMAiELGDMQA.
PhylomeDBiQ558Z0.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q558Z0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFQEEIAKQL SVLTEIEANK ILECIESTKN KDMADFAVPI PKLNKFKKLV
60 70 80 90 100
GKPDQLAIDF ASKIQLNDCI QGASATGNYL NFKVNRLLQV QEILKEVINQ
110 120 130 140 150
KEKYGMTEQG KGKKVIVEFS SPNIAKPFHA GHLRSTIIGN FMVNLFNELA
160 170 180 190 200
YETVSMNYLG DWGKQYGLLA VGFEKYGSEE ELLADPIKHL YNVYVQINGE
210 220 230 240 250
AEKEEEAKKK YAEEIAAGVE PTAPLQTTPT IHDTARAYFK RMEDGDAEAL
260 270 280 290 300
AIWKRFRDLS IVKYKDIYNR LNVKFDIYAG ESLVTEGMTI EFKKLQDKNL
310 320 330 340 350
LEDSQGAKVI DLSKPNKLGK VLVQKTDGTT LYITRDIAAA VDRKNNIGFD
360 370 380 390 400
KMYYVVASQQ DFHFRQLFDI LGKMDYQWQK DLTHINYGMV KGMSTRKGTV
410 420 430 440 450
VFLEDILNKT QKKMLKIMKQ NEQKFAEIED PEKVADIVGL SAVVIQDFNA
460 470 480 490 500
KRNKDYDFNW DRMLKSDGDT GPYLQYAHAR LCSLERKSGF EFNPNANLSL
510 520 530 540 550
LSEPEAFNLA ITIGRYPEII QLTHNQLEPS TLVGYLFELA HAVSSAHQVL
560 570 580
WIKDREKDVA EARFVLYWAA KVILGSGLRI LGLVPLERM
Length:589
Mass (Da):67,044
Last modified:May 24, 2005 - v1
Checksum:i557A91F67E0F08DE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000008 Genomic DNA. Translation: EAL71071.1.
RefSeqiXP_644926.1. XM_639834.1.

Genome annotation databases

EnsemblProtistsiDDB0231324; DDB0231324; DDB_G0272867.
GeneIDi8618605.
KEGGiddi:DDB_G0272867.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000008 Genomic DNA. Translation: EAL71071.1 .
RefSeqi XP_644926.1. XM_639834.1.

3D structure databases

ProteinModelPortali Q558Z0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231324.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231324 ; DDB0231324 ; DDB_G0272867 .
GeneIDi 8618605.
KEGGi ddi:DDB_G0272867.

Organism-specific databases

dictyBasei DDB_G0272867. argS1.

Phylogenomic databases

eggNOGi COG0018.
InParanoidi Q558Z0.
KOi K01887.
OMAi ELGDMQA.
PhylomeDBi Q558Z0.

Enzyme and pathway databases

Reactomei REACT_221378. Mitochondrial tRNA aminoacylation.

Miscellaneous databases

PROi Q558Z0.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiSYRC_DICDI
AccessioniPrimary (citable) accession number: Q558Z0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3