Q55898 (PPK_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Polyphosphate kinase
EC=2.7.4.1

Alternative name(s):
ATP-polyphosphate phosphotransferase
Polyphosphoric acid kinase

Gene names

Name:	ppk
Ordered Locus Names:	sll0290

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	728 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). HAMAP MF_00347
Catalytic activity	ATP + (phosphate)(n) = ADP + (phosphate)(n+1). HAMAP MF_00347
Post-translational modification	An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to histidine residues through a N-P bond By similarity. HAMAP MF_00347
Sequence similarities	Belongs to the polyphosphate kinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	polyphosphate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	polyphosphate kinase complex Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW polyphosphate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 728	728	Polyphosphate kinase HAMAP MF_00347		PRO_0000128665
Sites
	Active site	468	1	Phosphohistidine intermediate By similarity
	Active site	487	1	Phosphohistidine intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q55898 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 65F0A501464F6CC7	FASTA	728	82,607
	10 20 30 40 50 60 MIQAMPSAPT VDFKDPAYYF NRELSWLAFN QRVLHEGLDD RTPLLERLKF LAIFCSNLDE 70 80 90 100 110 120 FFMVRVAGLK QQVEANVTKL TADGRTPSQQ LKEISKSLRP LVYQQNQVFE YVLKEKLADE 130 140 150 160 170 180 GIFLNDYVDL SQEERQYLHQ FYDDHIFPVL TPLAVDPSHP FPYISNLSLN LGVVVRDPDT 190 200 210 220 230 240 DEELFARVKV PPTLPRFVAL PEDVCQPDPN KPWLWTGVPL EQVIAHNLAS LFPGMIIQEC 250 260 270 280 290 300 HLFRVTRNAD IAVEEDEADD LLLAIEEELR KRRVGKSAVR LEINASTPKN IRDRLMTDLG 310 320 330 340 350 360 LEEIDVYDID GLLGLKDLFF FLSLPAPHLK DEPWASVIPP RLKHVYEFVD GDEDGRVQQE 370 380 390 400 410 420 GIDIFTLIRQ GDILVHHPYQ SFTASVQQFI TQAAYDPHVL TIKMTLYRTS GDSPIVNALI 430 440 450 460 470 480 AAAENGKQVA VLVELKARFD EENNINWARK LEQYGVHVVY GLVGLKTHTK TVLVVRQEGP 490 500 510 520 530 540 DIRRYVHIGT GNYNPKTAKL YTDLGLITCR PELGNDLTNL FNFLTGYSRQ KDYQKLLVAP 550 560 570 580 590 600 VNMRERMVAM IEREADHCLN GGTGRIVAKM NSLVDTQIIR ALYAASQAGV QIDLIVRGIC 610 620 630 640 650 660 CLRPGVENVS ENIRVISVIG RLLEHSRIFY FHNGGEEEIY IGSADWMSRN LTRRVEAVVP 670 680 690 700 710 720 VEQPDLKQEL QSILGILLAD NRQAWELQPD GTYVQRRPAS PEQSQSSQAI FTAQAIAETT EDPELRSV

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA10660.1.
PIR	S76968.
RefSeq	NP_442590.1. NC_000911.1.
3D structure databases
ProteinModelPortal	Q55898.
ModBase	Search...
Protein-protein interaction databases
STRING	Q55898.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	952249.
GenomeReviews	Gene locus sll0290 in contig BA000022_GR.
KEGG	syn:sll0290.
NMPDR	fig|1148.1.peg.2691.
PATRIC	23842908. VBISynSp132158_2992.
Phylogenomic databases
eggNOG	COG0855.
HOGENOM	HBG341268.
OMA	DPTHPFP.
PhylomeDB	Q55898.
ProtClustDB	PRK05443.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0290-MONOMER.
Family and domain databases
HAMAP	MF_00347. Polyphosphate_kinase. [Tree]
InterPro	IPR003414. PP_kinase. [Graphical view]
KO	K00937.
Pfam	PF02503. PP_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF015589. PP_kinase. 1 hit.
TIGRFAMs	TIGR03705. Poly_P_kin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPK_SYNY3

Accession

Primary (citable) accession number: Q55898

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program