Reviewed, UniProtKB/Swiss-Prot Q55891 (PCYA_SYNY3)

Names and origin

Protein names

Recommended name:
    Phycocyanobilin:ferredoxin oxidoreductase
    EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	slr0116

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin By similarity. HAMAP MF_00618
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00618
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 248

248

Phycocyanobilin:ferredoxin oxidoreductase HAMAP MF_00618

PRO_0000216747

Secondary structure

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248

Helix Strand Turn

Details...

Helix

8 – 10

3

Helix

14 – 16

3

Helix

19 – 32

14

Helix

43 – 45

3

Beta strand

48 – 55

8

Beta strand

58 – 66

9

Beta strand

68 – 80

13

Turn

81 – 83

3

Beta strand

84 – 93

10

Helix

95 – 97

3

Beta strand

101 – 109

9

Beta strand

112 – 121

10

Helix

131 – 138

8

Beta strand

146 – 148

3

Helix

153 – 157

5

Beta strand

163 – 165

3

Helix

170 – 192

23

Helix

199 – 216

18

Helix

220 – 230

11

Helix

232 – 241

10

Sequences

	Sequence		Length	Mass (Da)
	Q55891-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: BEB10CEBCE5E515B	FASTA	248	28,129
	10 20 30 40 50 60 MAVTDLSLTN SSLMPTLNPM IQQLALAIAA SWQSLPLKPY QLPEDLGYVE GRLEGEKLVI 70 80 90 100 110 120 ENRCYQTPQF RKMHLELAKV GKGLDILHCV MFPEPLYGLP LFGCDIVAGP GGVSAAIADL 130 140 150 160 170 180 SPTQSDRQLP AAYQKSLAEL GQPEFEQQRE LPPWGEIFSE YCLFIRPSNV TEEERFVQRV 190 200 210 220 230 240 VDFLQIHCHQ SIVAEPLSEA QTLEHRQGQI HYCQQQQKND KTRRVLEKAF GEAWAERYMS QVLFDVIQ

References

[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BA000022 Genomic DNA. Translation: BAA10653.1.

PIR

S76709.

RefSeq

NP_442583.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2D1E	X-ray	1.51	A	1-248	[»]
2DKE	X-ray	2.50	A	1-248	[»]
3F0J	X-ray	1.30	A	1-248	[»]
3F0K	X-ray	1.50	A	1-248	[»]
3F0L	X-ray	1.30	A	1-248	[»]
3F0M	X-ray	1.50	A	1-248	[»]
3I8U	X-ray	1.48	X	1-248	[»]
3I94	X-ray	1.04	A	1-248	[»]
3I95	X-ray	1.40	A	1-248	[»]

ModBase

Search...

Protein-protein interaction databases

IntAct

Q55891. 1 interaction.

STRING

Q55891.

Genome annotation databases

GeneID

952260.

GenomeReviews

Gene locus slr0116 in contig BA000022_GR.

KEGG

syn:slr0116.

NMPDR

fig|1148.1.peg.2684.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

NOG27460.

HOGENOM

HBG561233.

OMA

NDKTRRV.

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-13954.
SSP1148:SLR0116-MONOMER.

Family and domain databases

HAMAP

MF_00618. Ferredoxin_bilin_red.
[Tree]

InterPro

IPR009249. Ferredoxin-dep_bilin_Rdtase.
[Graphical view]

Pfam

PF05996. Fe_bilin_red. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

PCYA_SYNY3

Accession

Primary (citable) accession number: Q55891

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	November 1, 1996
Last modified:	January 19, 2010
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)