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Q55863 (KPYK1_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate kinase 1

Short name=PK 1
EC=2.7.1.40
Gene names
Name:pyk1
Ordered Locus Names:sll0587
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length483 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium.

Potassium.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the pyruvate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 483483Pyruvate kinase 1
PRO_0000112085

Sites

Metal binding481Potassium By similarity
Metal binding501Potassium By similarity
Metal binding801Potassium By similarity
Metal binding2351Magnesium By similarity
Metal binding2591Magnesium By similarity
Binding site461Substrate By similarity
Binding site2581Substrate; via amide nitrogen By similarity
Binding site2591Substrate; via amide nitrogen By similarity
Binding site2911Substrate By similarity
Site2331Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55863 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: F53C2D402CCB8445

FASTA48353,105
        10         20         30         40         50         60 
MPALINPVKF MRPLSHRTKI VATIGPASSS VEVIRQMVDA GMNVARLNFS HGSYEDHATM 

        70         80         90        100        110        120 
VRLLRSVEQE MDTPITLLQD LQGPKIRIGQ LPGGEKQLRE GEKVSLVPVE IGDRHPGAVG 

       130        140        150        160        170        180 
IDYPHLATEA KVGERILLDD GLLEMKVVSI QDPEVICEVV TGGILKSRKG VNLPGLVLTL 

       190        200        210        220        230        240 
PSMTTKDKQD LEFGLSQGID WVSLSFVRKG EDIHTLKQFL AERGHPDLPV IAKIEKPQAI 

       250        260        270        280        290        300 
DNLEEIVAVS NGIMVARGDL GVEVNPEKVP RLQKEIIRRC NVRAIPVITA TQMLDSMIQN 

       310        320        330        340        350        360 
SRPTRAEASD VANAILDGTD AVMLSGESAV GQYPVKSVQM LRKIAEETEV GLHLVNNPPI 

       370        380        390        400        410        420 
ENTETHALSE ALVVIDGILD LKYIVTFTTS GFTSLLASNQ RPSVPVIAFT PSEKVYHSLN 

       430        440        450        460        470        480 
LVWGIIPFLI NEEFDTFEDL IQQAEVLLRD RKMVEKGDQL LIMAGIPTKI PRGTNFLKIH 


RIS 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10621.1.
PIRS76677.
RefSeqNP_442551.1. NC_000911.1.
YP_005652612.1. NC_017277.1.
YP_007452427.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55863.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55863. 1 interaction.
STRING1148.sll0587.

Proteomic databases

PaxDbQ55863.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10621; BAA10621; BAA10621.
GeneID12254004.
14618108.
952279.
KEGGsyn:sll0587.
syy:SYNGTS_2659.
syz:MYO_126840.
PATRIC23842826. VBISynSp132158_2952.

Phylogenomic databases

eggNOGCOG0469.
HOGENOMHOG000021558.
KOK00873.
OMAQRPEDIH.
OrthoDBEOG6GBMB0.
PhylomeDBQ55863.
ProtClustDBCLSK893613.

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPYK1_SYNY3
AccessionPrimary (citable) accession number: Q55863
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways