ID   Q55811_SYNY3            Unreviewed;       456 AA.
AC   Q55811;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 143.
DE   RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN   OrderedLocusNames=slr0091 {ECO:0000313|EMBL:BAA10564.1};
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Merismopediaceae;
OC   Synechocystis.
OX   NCBI_TaxID=1111708 {ECO:0000313|EMBL:BAA10564.1, ECO:0000313|Proteomes:UP000001425};
RN   [1] {ECO:0000313|EMBL:BAA10564.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC       ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; BA000022; BAA10564.1; -; Genomic_DNA.
DR   PIR; S76620; S76620.
DR   AlphaFoldDB; Q55811; -.
DR   SMR; Q55811; -.
DR   IntAct; Q55811; 3.
DR   STRING; 1148.gene:10500068; -.
DR   PaxDb; 1148-1001727; -.
DR   EnsemblBacteria; BAA10564; BAA10564; BAA10564.
DR   KEGG; syn:slr0091; -.
DR   eggNOG; COG1012; Bacteria.
DR   InParanoid; Q55811; -.
DR   PhylomeDB; Q55811; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IBA:GO_Central.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IBA:GO_Central.
DR   CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR036492};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001425}.
FT   DOMAIN          5..428
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   COILED          23..50
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   ACT_SITE        210
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU10007"
FT   ACT_SITE        244
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ   SEQUENCE   456 AA;  51188 MW;  579562C73A14786D CRC64;
     MNTAKTVVAE QRDFFRQGKT KSVQDRLTAL AKLKTQIQAQ EEEIIKALKQ DFGKPTFESY
     VNEILGVIRE INYYQKHLQQ WSKPQRVGTN LMVFPASAQL RPEPLGVVLI ISPWNYPFYL
     CLMPLIGAIA AGNCVVVKPS EYTPAISGVI TRLIQNVFSP AWATVVEGDE TISQQLLQEK
     FDHIFFTGSP RVGRLIMAAA AEQLTPVTLE LGGKSPCVVD REINLQETAK RIMWGKLVNA
     GQTCVAPDYL LVEQSCLEQL LPALQQAIQM LFGENPAHSP DYTRIVNQQQ WSRLVSLLSH
     GKVITRGDHN EGDRYIAPTL IIDPDLNSPL MQEEIFGPIL PILTYQSLSE AIDFINIKPK
     PLALYFFSNN RQKQEEILQS TSSGSVCLND ILLHLTVTDL PFGGVGESGM GRYHGKATFD
     TLSNYKSILR RPFWGETNLR YSPYGKKMNL IKKLFS
//