Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q55801

- RNH_SYNY3

UniProt

Q55801 - RNH_SYNY3

Protein

Ribonuclease HI

Gene

rnhA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.By similarity

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.

    Cofactori

    Binds 1 magnesium ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi13 – 131Magnesium 1By similarity
    Metal bindingi13 – 131Magnesium 2By similarity
    Metal bindingi52 – 521Magnesium 1By similarity
    Metal bindingi74 – 741Magnesium 1By similarity
    Metal bindingi139 – 1391Magnesium 2By similarity

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. nucleic acid binding Source: InterPro
    3. RNA-DNA hybrid ribonuclease activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. RNA catabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Ligandi

    Magnesium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease HI (EC:3.1.26.4)
    Short name:
    RNase HI
    Gene namesi
    Name:rnhA
    Ordered Locus Names:slr0080
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 160160Ribonuclease HIPRO_0000195408Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    IntActiQ55801. 1 interaction.
    STRINGi1148.slr0080.

    Structurei

    3D structure databases

    ProteinModelPortaliQ55801.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 147144RNase HAdd
    BLAST

    Sequence similaritiesi

    Belongs to the RNase H family.Curated
    Contains 1 RNase H domain.Curated

    Phylogenomic databases

    eggNOGiCOG0328.
    HOGENOMiHOG000040465.
    KOiK03469.
    OMAiAYIVNAV.
    OrthoDBiEOG696BTR.
    PhylomeDBiQ55801.

    Family and domain databases

    Gene3Di3.30.420.10. 1 hit.
    HAMAPiMF_00042. RNase_H.
    InterProiIPR022892. RNaseH.
    IPR012337. RNaseH-like_dom.
    IPR002156. RNaseH_domain.
    [Graphical view]
    PfamiPF00075. RNase_H. 1 hit.
    [Graphical view]
    SUPFAMiSSF53098. SSF53098. 1 hit.
    PROSITEiPS50879. RNASE_H. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q55801-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASTPNSVTL YTDGACSMNP GPGGYGAVIL YGDGRREELS AGYKMTTNNR    50
    MEIMGAIAAL SHLQEPSQVL LYTDSRYMVD AMSKGWAKKW KANGWQRNAK 100
    EKAKNPDLWE TMLTLCEKHQ VTFQWVKAHA GNKENERCDR LAVAAYQNNP 150
    NLVDEGFGKF 160
    Length:160
    Mass (Da):17,856
    Last modified:November 1, 1996 - v1
    Checksum:iF25924F536CBF766
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA10553.1.
    PIRiS76609.
    RefSeqiNP_442483.1. NC_000911.1.
    YP_005652544.1. NC_017277.1.
    YP_007452359.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA10553; BAA10553; BAA10553.
    GeneIDi952423.
    KEGGisyn:slr0080.
    syy:SYNGTS_2591.
    syz:MYO_126160.
    PATRICi23842672. VBISynSp132158_2875.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA10553.1 .
    PIRi S76609.
    RefSeqi NP_442483.1. NC_000911.1.
    YP_005652544.1. NC_017277.1.
    YP_007452359.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali Q55801.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q55801. 1 interaction.
    STRINGi 1148.slr0080.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA10553 ; BAA10553 ; BAA10553 .
    GeneIDi 952423.
    KEGGi syn:slr0080.
    syy:SYNGTS_2591.
    syz:MYO_126160.
    PATRICi 23842672. VBISynSp132158_2875.

    Phylogenomic databases

    eggNOGi COG0328.
    HOGENOMi HOG000040465.
    KOi K03469.
    OMAi AYIVNAV.
    OrthoDBi EOG696BTR.
    PhylomeDBi Q55801.

    Family and domain databases

    Gene3Di 3.30.420.10. 1 hit.
    HAMAPi MF_00042. RNase_H.
    InterProi IPR022892. RNaseH.
    IPR012337. RNaseH-like_dom.
    IPR002156. RNaseH_domain.
    [Graphical view ]
    Pfami PF00075. RNase_H. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53098. SSF53098. 1 hit.
    PROSITEi PS50879. RNASE_H. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
      Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
      DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27184 / PCC 6803 / N-1.
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiRNH_SYNY3
    AccessioniPrimary (citable) accession number: Q55801
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3