Reviewed, UniProtKB/Swiss-Prot Q55797 (GMHA_SYNY3)

Names and origin

Protein names

Recommended name:
    Phosphoheptose isomerase
    EC=5.3.1.-
Alternative name(s):
    Sedoheptulose 7-phosphate isomerase

Gene names

Name:	gmhA
Ordered Locus Names:	sll0083

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-mannoheptose 7-phosphate By similarity.
Catalytic activity	D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate. HAMAP MF_00067
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the SIS family. GmhA subfamily. Contains 1 SIS domain.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide core region biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	D-sedoheptulose 7-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Phosphoheptose isomerase HAMAP MF_00067		PRO_0000136547
Regions
	Domain	31 – 186	156	SIS

Sequences

	Sequence		Length	Mass (Da)
	Q55797-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: CEA722DA56E11DBD	FASTA	194	21,137
	10 20 30 40 50 60 MSEWVEQRLQ SLAKAFDQSY CGAIEAVVDL ICQRFQAGNK LLICGNGGSA ADAQHLAAEF 70 80 90 100 110 120 VGRFHFNRQA LPAIALTANS SILTSVSNDY TYDIVFSRQV EALGQPGDIL WGLSTSGKST 130 140 150 160 170 180 NVLHALKCAK DKGLHTIGMA GNNGGLFQEF ADYPLFVADK NTPCIQEVHL MTYHHICEQV 190 ESRLFAQKSV GIKV

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA10549.1.
PIR	S76605.
RefSeq	NP_442479.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q55797.
Genome annotation databases
GeneID	952344.
GenomeReviews	Gene locus sll0083 in contig BA000022_GR.
KEGG	syn:sll0083.
NMPDR	fig|1148.1.peg.2580.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q55797.
OMA	NDYGFER
Enzyme and pathway databases
BioCyc	SSP1148:SLL0083-MON.
Family and domain databases
HAMAP	MF_00067. [Tree]
InterPro	IPR004515. Phosphoheptose_Isoase_subgr. IPR020620. Phosphoheptose_isomerase. [Graphical view]
TIGRFAMs	TIGR00441. gmhA. 1 hit.
PROSITE	PS51464. SIS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GMHA_SYNY3

Accession

Primary (citable) accession number: Q55797

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	November 24, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)