Reviewed, UniProtKB/Swiss-Prot Q55794 (ARSA_SYNY3)

Names and origin

Protein names

Recommended name:
    Putative arsenical pump-driving ATPase
    EC=3.6.3.16
Alternative name(s):
    Arsenite-translocating ATPase
    Arsenical resistance ATPase
    Arsenite-transporting ATPase

Gene names

Ordered Locus Names:

sll0086

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Anion-transporting ATPase. Catalyzes the extrusion of arsenite By similarity.
Catalytic activity	ATP + H2O + arsenite(In) = ADP + phosphate + arsenite(Out).
Sequence similarities	Belongs to the arsA ATPase family.

Ontologies

Keywords
Biological process	Arsenical resistance
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular metal ion homeostasis Inferred from electronic annotation. Source: InterPro response to arsenic Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW arsenite transmembrane-transporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 396	396	Putative arsenical pump-driving ATPase		PRO_0000152264
Regions
	Nucleotide binding	8 – 15	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q55794-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 0D768B195B24DEB3	FASTA	396	44,626
	10 20 30 40 50 60 MRVILMTGKG GVGKTSVAAA TGLRCAELGH KTLVLSTDPA HSLADSFDLE LGHEPRLVKE 70 80 90 100 110 120 NLWGAELDAL MELEGNWGAV KRYITQVLQA RGLDGVQAEE LAILPGMDEI FGLVRMKRHY 130 140 150 160 170 180 DEADYDVLII DSAPTGTALR LLSLPEVGGW YMRRFYKPLQ GMSVALRPLV EPLFRPIAGF 190 200 210 220 230 240 SLPDKEVMDA PYEFYEQIEA LEKVLTDNTQ TSVRLVTNPE KMVLKESLRA HAYLSLYNVS 250 260 270 280 290 300 TDLVIANRIL PETIDDPFFQ RWKSNQQVYK QEIYDNFHPL PVKEAPLFSE EMCGLAALER 310 320 330 340 350 360 LKDTLYKDED PSQVYYKENT INIVQGSNND YSLELYLPGI PKEQIQLNKT GDELNVRIGN 370 380 390 HRRNLVLPQA LAALSPAGAK MEDDYLKIRF AEAVKR

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA10546.1.
PIR	S76602.
RefSeq	NP_442476.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q55794.
Genome annotation databases
GeneID	952347.
GenomeReviews	Gene locus sll0086 in contig BA000022_GR.
KEGG	syn:sll0086.
NMPDR	fig|1148.1.peg.2577.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG564762.
OMA	KEVMDAP.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0086-MON.
Family and domain databases
InterPro	IPR003348. ATPase_anion-transp. IPR008978. HSP20-like_chaperone. [Graphical view]
Pfam	PF02374. ArsA_ATPase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARSA_SYNY3

Accession

Primary (citable) accession number: Q55794

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	December 15, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)