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Protein

Lysozyme D

Gene

alyD-1

more
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Has antibacterial activity.By similarity

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.Curated

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

GO - Molecular functioni

  • lysozyme activity Source: UniProtKB

GO - Biological processi

  • cytolysis Source: UniProtKB-KW
  • defense response to Gram-positive bacterium Source: UniProtKB
  • peptidoglycan catabolic process Source: dictyBase

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Lysozyme D (EC:3.2.1.17)
Alternative name(s):
1,4-beta-N-acetylmuramidase D
Gene namesi
Name:alyD-1
ORF Names:DDB_G0273197
AND
Name:alyD-2
ORF Names:DDB_G0273731
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0273197 alyD-1
DDB_G0273731 alyD-2

Subcellular locationi

  • Cytoplasmic vesicle lumen By similarity

GO - Cellular componenti

  • cytoplasmic vesicle Source: UniProtKB
  • cytoplasmic vesicle lumen Source: UniProtKB-SubCell
  • vesicle lumen Source: UniProtKB

Keywords - Cellular componenti

Cytoplasmic vesicle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19By similarityAdd BLAST19
ChainiPRO_000031592020 – 260Lysozyme DBy similarityAdd BLAST241

Post-translational modificationi

Contains disulfide bonds.By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ556Y7

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi79 – 149Ser-richSequence analysisAdd BLAST71

Sequence similaritiesi

Belongs to the dictyostelium lysozyme family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ556Y7
OMAiQRFGCGV
PhylomeDBiQ556Y7

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q556Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLVTLILL IFVLTVSGQY SCSNPCYGNM CCSIPSNNEY YLTTFCDEST
60 70 80 90 100
ACGTPCSAQT YFTADSQRFG CGVTLTICST SGGSTTTGGT GSAGTSTSSG
110 120 130 140 150
SGSGSGSGSG SGSGSGSGTS GSSSSGSSSG SGSGSSSGSG GSSGSGSGST
160 170 180 190 200
METGGFYGVC VKAITIDAGP NISVEEEAGM AIIDASSQIC QDLFGSSSCG
210 220 230 240 250
WSDKRSITAV QSSVEDGFPV NKPFNVTFED YNKIISNSLI LDQQCSNKNN
260
CKYNKLELMK
Length:260
Mass (Da):26,057
Last modified:May 2, 2006 - v1
Checksum:i8A118309949B6010
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000011 Genomic DNA Translation: EAL70556.1
AAFI02000009 Genomic DNA Translation: EAL70816.1
RefSeqiXP_644482.1, XM_639390.1
XP_644768.1, XM_639676.1

Genome annotation databases

EnsemblProtistsiEAL70556; EAL70556; DDB_G0273731
EAL70816; EAL70816; DDB_G0273197
GeneIDi8618870
8619106
KEGGiddi:DDB_G0273197
ddi:DDB_G0273731

Entry informationi

Entry nameiLYSD_DICDI
AccessioniPrimary (citable) accession number: Q556Y7
Secondary accession number(s): Q86JT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 2, 2006
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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