Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable flavin-containing monoamine oxidase C

Gene

maoC-1

more
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.Curated

Catalytic activityi

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

Cofactori

FADBy similarity

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein

Enzyme and pathway databases

ReactomeiR-DDI-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
R-DDI-181430 Norepinephrine Neurotransmitter Release Cycle
R-DDI-379397 Enzymatic degradation of dopamine by COMT
R-DDI-379398 Enzymatic degradation of Dopamine by monoamine oxidase
R-DDI-380612 Metabolism of serotonin

Names & Taxonomyi

Protein namesi
Recommended name:
Probable flavin-containing monoamine oxidase C (EC:1.4.3.4)
Gene namesi
Name:maoC-1
ORF Names:DDB_G0272584
AND
Name:maoC-2
ORF Names:DDB_G0273991
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0272584 maoC-1
DDB_G0273991 maoC-2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003286301 – 467Probable flavin-containing monoamine oxidase CAdd BLAST467

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei402S-8alpha-FAD cysteineBy similarity1

Proteomic databases

PaxDbiQ556K4

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0266408

Structurei

3D structure databases

ProteinModelPortaliQ556K4
SMRiQ556K4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavin monoamine oxidase family.Curated

Phylogenomic databases

eggNOGiKOG0029 Eukaryota
ENOG410XSNC LUCA
InParanoidiQ556K4
KOiK00274
PhylomeDBiQ556K4

Family and domain databases

Gene3Di3.50.50.60, 4 hits
InterProiView protein in InterPro
IPR002937 Amino_oxidase
IPR036188 FAD/NAD-bd_sf
IPR001613 Flavin_amine_oxidase
PfamiView protein in Pfam
PF01593 Amino_oxidase, 1 hit
PRINTSiPR00757 AMINEOXDASEF
SUPFAMiSSF51905 SSF51905, 2 hits

Sequencei

Sequence statusi: Complete.

Q556K4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIIYDTIII GGGMSGLKTA YDLKKSNFKI LVLEARNRFG GRTDSIKIGD
60 70 80 90 100
GWVDAGGQWL GKKNPNLKQL CNELKLETYK QFYQGKTVFD IYDDGLIKSF
110 120 130 140 150
DESSPNFDLC EIGLGYINPI IQTIKEVGKN IDFSKCSKES PIMLSLEKLT
160 170 180 190 200
VSEWLRVCGY GESVKFFIWF CKMSVASSSD DISILFFFKY INSINGIESL
210 220 230 240 250
FISDDDCTES DRIIGGSSMV SERIVSFLKD DCKLNCEVTL IDQISHKNGR
260 270 280 290 300
LVKITTSKNE IYYCRNVVST IPPMLLKNVI FKPDLPIEKQ RLKNEMEMGN
310 320 330 340 350
TIKVIVIYDS VFWRDQGYNG KSQSFVGPIY QSFDNCTNDL SVKSIIGFIN
360 370 380 390 400
GKEEIKYWYS KSLEERRSAV LNQYSKYWGP KALNPIHYIE RNWSLDKYSA
410 420 430 440 450
GCFMGVCKSG DIISQCNNYY TQPHGNIHWA GTETSTQWYG HMEGAITSSK
460
RVVNEILKTS LKSKSKL
Length:467
Mass (Da):53,140
Last modified:May 2, 2006 - v1
Checksum:i1D6FC3750E9C223E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000011 Genomic DNA Translation: EAL70429.1
AAFI02000009 Genomic DNA Translation: EAL70929.1
RefSeqiXP_644354.1, XM_639262.1
XP_645060.1, XM_639968.1

Genome annotation databases

EnsemblProtistsiEAL70429; EAL70429; DDB_G0273991
EAL70929; EAL70929; DDB_G0272584
GeneIDi8618735
8619241
KEGGiddi:DDB_G0272584
ddi:DDB_G0273991

Similar proteinsi

Entry informationi

Entry nameiAOFC_DICDI
AccessioniPrimary (citable) accession number: Q556K4
Secondary accession number(s): Q86AM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 2, 2006
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health