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Q556K3

- AOFB_DICDI

UniProt

Q556K3 - AOFB_DICDI

Protein

Probable flavin-containing monoamine oxidase B

Gene

maoB-1

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Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (02 May 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

    Cofactori

    FAD.

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable flavin-containing monoamine oxidase B (EC:1.4.3.4)
    Gene namesi
    Name:maoB-1
    ORF Names:DDB_G0272582
    AND
    Name:maoB-2
    ORF Names:DDB_G0273993
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0272582. maoB-1.
    DDB_G0273993. maoB-2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 471471Probable flavin-containing monoamine oxidase BPRO_0000328629Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei406 – 4061S-8alpha-FAD cysteineBy similarity

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0231711.

    Structurei

    3D structure databases

    ProteinModelPortaliQ556K3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the flavin monoamine oxidase family.Curated

    Phylogenomic databases

    eggNOGiCOG1231.
    OMAiSTWNPFV.
    PhylomeDBiQ556K3.

    Family and domain databases

    InterProiIPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view]
    PfamiPF01593. Amino_oxidase. 1 hit.
    [Graphical view]
    PRINTSiPR00757. AMINEOXDASEF.

    Sequencei

    Sequence statusi: Complete.

    Q556K3-1 [UniParc]FASTAAdd to Basket

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    MEMEILYNYD TIIIGGGLSG LNTAYDLKKS NFKILVLEAR NRFGGRTDSV    50
    KVGDGWVDAG GQWLGTNNPN LKQLCKELKL ETYKQFYQGK TVFDIYDDGL 100
    IKSFDESSPN FDLCEIGLGN INPIIRAIKE VMKNIDFSKC SKESPIMLSL 150
    EKLTVSEWLR VCGYGESVKF FNWFCKMSVA SSSDDISILF LLKYVNSING 200
    FESLFISDDD CTESDRIIGG SSMVSERIVS YLKDDCKLNC EVTLIDQISH 250
    KNSRLIKITT SNNENYYCRN VVSTIPPMLL KNVIFKPDLP IEKQRLKNEM 300
    EMGNTIKVIV IYDSVFWRDQ GYNGKSQSFV GPIYQSFDNC TNDLSVKSII 350
    GFINGKEEIK YWYSKSLEER RSAVLNQYSK YWGPKALNPI HYIERNWSLD 400
    KYSAGCFMGV CKSGDIISQC NNYYTQPHGN IHWAGTETST QWYGHMEGAI 450
    TSSKRVVNEI LKNSLNSKSK L 471
    Length:471
    Mass (Da):53,612
    Last modified:May 2, 2006 - v1
    Checksum:i76D9EF17F67950F0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000011 Genomic DNA. Translation: EAL70430.1.
    AAFI02000009 Genomic DNA. Translation: EAL70928.1.
    RefSeqiXP_644355.1. XM_639263.1.
    XP_645059.1. XM_639967.1.

    Genome annotation databases

    EnsemblProtistsiDDB0231711; DDB0231711; DDB_G0272582.
    DDB0266407; DDB0266407; DDB_G0273993.
    GeneIDi8618734.
    8619242.
    KEGGiddi:DDB_G0272582.
    ddi:DDB_G0273993.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000011 Genomic DNA. Translation: EAL70430.1 .
    AAFI02000009 Genomic DNA. Translation: EAL70928.1 .
    RefSeqi XP_644355.1. XM_639263.1.
    XP_645059.1. XM_639967.1.

    3D structure databases

    ProteinModelPortali Q556K3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0231711.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0231711 ; DDB0231711 ; DDB_G0272582 .
    DDB0266407 ; DDB0266407 ; DDB_G0273993 .
    GeneIDi 8618734.
    8619242.
    KEGGi ddi:DDB_G0272582.
    ddi:DDB_G0273993.

    Organism-specific databases

    dictyBasei DDB_G0272582. maoB-1.
    DDB_G0273993. maoB-2.

    Phylogenomic databases

    eggNOGi COG1231.
    OMAi STWNPFV.
    PhylomeDBi Q556K3.

    Family and domain databases

    InterProi IPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view ]
    Pfami PF01593. Amino_oxidase. 1 hit.
    [Graphical view ]
    PRINTSi PR00757. AMINEOXDASEF.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    2. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiAOFB_DICDI
    AccessioniPrimary (citable) accession number: Q556K3
    Secondary accession number(s): Q86AM6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: May 2, 2006
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Caution

    The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3