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Q556K3

- AOFB_DICDI

UniProt

Q556K3 - AOFB_DICDI

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Protein
Probable flavin-containing monoamine oxidase B
Gene
maoB-1, DDB_G0272582
maoB-2, DDB_G0273993
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

Cofactori

FAD.

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Organism-specific databases

Protein namesi
Recommended name:
Probable flavin-containing monoamine oxidase B (EC:1.4.3.4)
Gene namesi
Name:maoB-1
ORF Names:DDB_G0272582
AND
Name:maoB-2
ORF Names:DDB_G0273993
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence
dictyBaseiDDB_G0272582. maoB-1.
DDB_G0273993. maoB-2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 471471Probable flavin-containing monoamine oxidase B
PRO_0000328629Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei406 – 4061S-8alpha-FAD cysteine By similarity

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231711.

Structurei

3D structure databases

ProteinModelPortaliQ556K3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1231.
OMAiSTWNPFV.
PhylomeDBiQ556K3.

Family and domain databases

InterProiIPR002937. Amino_oxidase.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSiPR00757. AMINEOXDASEF.

Sequencei

Sequence statusi: Complete.

Q556K3-1 [UniParc]FASTAAdd to Basket

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MEMEILYNYD TIIIGGGLSG LNTAYDLKKS NFKILVLEAR NRFGGRTDSV    50
KVGDGWVDAG GQWLGTNNPN LKQLCKELKL ETYKQFYQGK TVFDIYDDGL 100
IKSFDESSPN FDLCEIGLGN INPIIRAIKE VMKNIDFSKC SKESPIMLSL 150
EKLTVSEWLR VCGYGESVKF FNWFCKMSVA SSSDDISILF LLKYVNSING 200
FESLFISDDD CTESDRIIGG SSMVSERIVS YLKDDCKLNC EVTLIDQISH 250
KNSRLIKITT SNNENYYCRN VVSTIPPMLL KNVIFKPDLP IEKQRLKNEM 300
EMGNTIKVIV IYDSVFWRDQ GYNGKSQSFV GPIYQSFDNC TNDLSVKSII 350
GFINGKEEIK YWYSKSLEER RSAVLNQYSK YWGPKALNPI HYIERNWSLD 400
KYSAGCFMGV CKSGDIISQC NNYYTQPHGN IHWAGTETST QWYGHMEGAI 450
TSSKRVVNEI LKNSLNSKSK L 471
Length:471
Mass (Da):53,612
Last modified:May 2, 2006 - v1
Checksum:i76D9EF17F67950F0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000011 Genomic DNA. Translation: EAL70430.1.
AAFI02000009 Genomic DNA. Translation: EAL70928.1.
RefSeqiXP_644355.1. XM_639263.1.
XP_645059.1. XM_639967.1.

Genome annotation databases

EnsemblProtistsiDDB0231711; DDB0231711; DDB_G0272582.
DDB0266407; DDB0266407; DDB_G0273993.
GeneIDi8618734.
8619242.
KEGGiddi:DDB_G0272582.
ddi:DDB_G0273993.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000011 Genomic DNA. Translation: EAL70430.1 .
AAFI02000009 Genomic DNA. Translation: EAL70928.1 .
RefSeqi XP_644355.1. XM_639263.1.
XP_645059.1. XM_639967.1.

3D structure databases

ProteinModelPortali Q556K3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231711.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231711 ; DDB0231711 ; DDB_G0272582 .
DDB0266407 ; DDB0266407 ; DDB_G0273993 .
GeneIDi 8618734.
8619242.
KEGGi ddi:DDB_G0272582.
ddi:DDB_G0273993.

Organism-specific databases

dictyBasei DDB_G0272582. maoB-1.
DDB_G0273993. maoB-2.

Phylogenomic databases

eggNOGi COG1231.
OMAi STWNPFV.
PhylomeDBi Q556K3.

Family and domain databases

InterProi IPR002937. Amino_oxidase.
IPR001613. Flavin_amine_oxidase.
[Graphical view ]
Pfami PF01593. Amino_oxidase. 1 hit.
[Graphical view ]
PRINTSi PR00757. AMINEOXDASEF.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiAOFB_DICDI
AccessioniPrimary (citable) accession number: Q556K3
Secondary accession number(s): Q86AM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 2, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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