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Protein

Probable flavin-containing monoamine oxidase B

Gene

maoB-1

more
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

Cofactori

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Probable flavin-containing monoamine oxidase B (EC:1.4.3.4)
Gene namesi
Name:maoB-1
ORF Names:DDB_G0272582
AND
Name:maoB-2
ORF Names:DDB_G0273993
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0272582. maoB-1.
DDB_G0273993. maoB-2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 471471Probable flavin-containing monoamine oxidase BPRO_0000328629Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei406 – 4061S-8alpha-FAD cysteineBy similarity

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231711.

Structurei

3D structure databases

ProteinModelPortaliQ556K3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavin monoamine oxidase family.Curated

Phylogenomic databases

eggNOGiCOG1231.
InParanoidiQ556K3.
OMAiMAGSIKF.
PhylomeDBiQ556K3.

Family and domain databases

InterProiIPR002937. Amino_oxidase.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSiPR00757. AMINEOXDASEF.

Sequencei

Sequence statusi: Complete.

Q556K3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMEILYNYD TIIIGGGLSG LNTAYDLKKS NFKILVLEAR NRFGGRTDSV
60 70 80 90 100
KVGDGWVDAG GQWLGTNNPN LKQLCKELKL ETYKQFYQGK TVFDIYDDGL
110 120 130 140 150
IKSFDESSPN FDLCEIGLGN INPIIRAIKE VMKNIDFSKC SKESPIMLSL
160 170 180 190 200
EKLTVSEWLR VCGYGESVKF FNWFCKMSVA SSSDDISILF LLKYVNSING
210 220 230 240 250
FESLFISDDD CTESDRIIGG SSMVSERIVS YLKDDCKLNC EVTLIDQISH
260 270 280 290 300
KNSRLIKITT SNNENYYCRN VVSTIPPMLL KNVIFKPDLP IEKQRLKNEM
310 320 330 340 350
EMGNTIKVIV IYDSVFWRDQ GYNGKSQSFV GPIYQSFDNC TNDLSVKSII
360 370 380 390 400
GFINGKEEIK YWYSKSLEER RSAVLNQYSK YWGPKALNPI HYIERNWSLD
410 420 430 440 450
KYSAGCFMGV CKSGDIISQC NNYYTQPHGN IHWAGTETST QWYGHMEGAI
460 470
TSSKRVVNEI LKNSLNSKSK L
Length:471
Mass (Da):53,612
Last modified:May 1, 2006 - v1
Checksum:i76D9EF17F67950F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000011 Genomic DNA. Translation: EAL70430.1.
AAFI02000009 Genomic DNA. Translation: EAL70928.1.
RefSeqiXP_644355.1. XM_639263.1.
XP_645059.1. XM_639967.1.

Genome annotation databases

EnsemblProtistsiDDB0231711; DDB0231711; DDB_G0272582.
DDB0266407; DDB0266407; DDB_G0273993.
GeneIDi8618734.
8619242.
KEGGiddi:DDB_G0272582.
ddi:DDB_G0273993.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000011 Genomic DNA. Translation: EAL70430.1.
AAFI02000009 Genomic DNA. Translation: EAL70928.1.
RefSeqiXP_644355.1. XM_639263.1.
XP_645059.1. XM_639967.1.

3D structure databases

ProteinModelPortaliQ556K3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB_0231711.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0231711; DDB0231711; DDB_G0272582.
DDB0266407; DDB0266407; DDB_G0273993.
GeneIDi8618734.
8619242.
KEGGiddi:DDB_G0272582.
ddi:DDB_G0273993.

Organism-specific databases

dictyBaseiDDB_G0272582. maoB-1.
DDB_G0273993. maoB-2.

Phylogenomic databases

eggNOGiCOG1231.
InParanoidiQ556K3.
OMAiMAGSIKF.
PhylomeDBiQ556K3.

Family and domain databases

InterProiIPR002937. Amino_oxidase.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSiPR00757. AMINEOXDASEF.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiAOFB_DICDI
AccessioniPrimary (citable) accession number: Q556K3
Secondary accession number(s): Q86AM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 7, 2008
Last sequence update: May 1, 2006
Last modified: January 6, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.