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Reviewed, UniProtKB/Swiss-Prot Q556I2 (AEDO_DICDI)

Last modified September 22, 2009. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable 2-aminoethanethiol dioxygenase
    EC=1.13.11.19
Alternative name(s):
    Cysteamine dioxygenase
Gene names
Name: ado-1
ORF Names: DDB_G0273031
AND
Name: ado-2
ORF Names: DDB_G0274043
OrganismDictyostelium discoideum (Slime mold) [Complete proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

2-aminoethanethiol + O2 = hypotaurine.

Cofactor

Iron By similarity.

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.

Ontologies

Keywords
   LigandIron
Metal-binding
   Molecular functionDioxygenase
Oxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncysteamine dioxygenase activity

Inferred from electronic annotation. Source: EC

iron ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 231231Probable 2-aminoethanethiol dioxygenase
PRO_0000353848

Regions

Compositional bias201 – 2044Poly-Ile
Compositional bias206 – 22924Asn-rich

Sequences

Sequence LengthMass (Da)Tools
Q556I2-1 [UniParc].

Last modified May 2, 2006. Version 1.
Checksum: C8B566974F8329C4

FASTA23126,309
        10         20         30         40         50         60 
MTILKQLITK ANLILPSVDK KVATLDSLVS VFKEIKCKDL KIDKPLTLTK PIGNGKKVFY 

        70         80         90        100        110        120 
YPLVENEKFT LAIFAFPPNT CIPTHDHPQM TVLSKVLYGS ISCDSFDWID NTSNVKKQGK 

       130        140        150        160        170        180 
AIYTGTNILN SNDEKVKITL PNENNIHRFQ SGDEHCAVLD LLYPPYDSNF YRSCTYYRPT 

       190        200        210        220        230 
SVNGSIVDLM PYYPDFDCEE IIIIPNYNNN NNNNNNNNNN NNNNNNNNNK K 

« Hide

References

[1]"Sequence and analysis of chromosome 2 of Dictyostelium discoideum."
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.
Nature 418:79-85(2002) [PubMed: 12097910] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed: 15875012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.

Cross-references

Sequence databases

AC116984 Genomic DNA. Translation: AAO51306.1.
AAFI02000011 Genomic DNA. Translation: EAL70455.1.
AAFI02000009 Genomic DNA. Translation: EAL71153.1.
RefSeqXP_644380.1.
XP_645033.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3395517.
3396198.
GenomeReviewsGene locus ado-2 in contig CM000151_GR.
KEGGddi:DDBDRAFT_0217097.
ddi:DDBDRAFT_0217434.

Organism-specific databases

dictyBaseDDB_G0273031. ado-1.
DDB_G0274043. ado-2.

Family and domain databases

InterProIPR012864. DUF1637.
[Graphical view]
PANTHERPTHR22966. DUF1637. 1 hit.
PfamPF07847. DUF1637. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAEDO_DICDI
AccessionPrimary (citable) accession number: Q556I2
Secondary accession number(s): Q86K19
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 2, 2006
Last modified: September 22, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents