Q556I2 (AEDO_DICDI) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 31.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable 2-aminoethanethiol dioxygenase EC=1.13.11.19 Alternative name(s): Cysteamine dioxygenase | |||||||||
| Gene names |
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| Organism | Dictyostelium discoideum (Slime mold) | |||||||||
| Taxonomic identifier | 44689 [NCBI] | |||||||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 218 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 2-aminoethanethiol + O2 = hypotaurine. |
| Cofactor | Iron By similarity. |
| Caution | The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2. |
| Sequence caution | The sequence EAL70455.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence EAL71153.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Molecular function | cysteamine dioxygenase activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 218 | 218 | Probable 2-aminoethanethiol dioxygenase | PRO_0000353848 | |||
Sequences
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References
| [1] | "Sequence and analysis of chromosome 2 of Dictyostelium discoideum." Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A. Nature 418:79-85(2002) [PubMed: 12097910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
| [2] | "The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. Kuspa A.Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AAFI02000011 Genomic DNA. Translation: EAL70455.1. Sequence problems. AAFI02000009 Genomic DNA. Translation: EAL71153.1. Sequence problems. |
| RefSeq | XP_644380.1. XM_639288.1. XP_645033.1. XM_639941.1. |
3D structure databases | |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q556I2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblProtists | DDB0217097; DDB0217097; DDB_G0273031. DDB0217434; DDB0217434; DDB_G0274043. |
| GeneID | 8618710. 8619266. |
| GenomeReviews | Gene locus ado-2 in contig CM000151_GR. |
| KEGG | ddi:DDB_G0273031. ddi:DDB_G0274043. |
Organism-specific databases | |
| dictyBase | DDB_G0273031. DDB_G0274043. |
Phylogenomic databases | |
| eggNOG | KOG4281. |
| GeneTree | EPrGT00050000003190. |
| OMA | NENNIHR. |
| PhylomeDB | Q556I2. |
| ProtClustDB | CLSZ2431087. |
Family and domain databases | |
| InterPro | IPR011051. Cupin_RmlC_type. IPR012864. Cysteamine_dioxygenase. IPR014710. RmlC-like_jellyroll. [Graphical view] |
| Gene3D | G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit. |
| Pfam | PF07847. DUF1637. 1 hit. [Graphical view] |
| SUPFAM | SSF51182. RmlC_like_cupin. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | AEDO_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q556I2 Secondary accession number(s): Q86K19 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |

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