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Q55684 (UPPP_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:sll0210
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 326326Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151226

Regions

Transmembrane11 – 3121Helical; Potential
Transmembrane42 – 6221Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane165 – 18521Helical; Potential
Transmembrane212 – 23221Helical; Potential
Transmembrane242 – 26221Helical; Potential
Transmembrane272 – 29221Helical; Potential
Transmembrane304 – 32421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q55684 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: D11C934FB8F23FFA

FASTA32635,077
        10         20         30         40         50         60 
MSPRQLNFLS AFSLSVAIAV VYHQAWGIAV AQPILPSEAV ETGVISNGIS INLFQAFVLG 

        70         80         90        100        110        120 
FIQGATEFLP ISSTAHLKAV PMALGWGDPG VAFTAVIQLG SIGAVFWYFW EDLTGIAKGI 

       130        140        150        160        170        180 
IKAVQTRQYD SLEFKLGLGI GLGTIPIVFF GLLMKLLVQD LDNSFFRSLS TIAIASIVMA 

       190        200        210        220        230        240 
LLLALAEKLG THRRPFEKLR WQDGLIMGTA QALALIPGVS RSGSTLTAGL FINLERAAAA 

       250        260        270        280        290        300 
RFSFLLGIPA ITIAGLVELK GLLDKNLSND AILPLIVGTI SSAVFSYLAI AWLIKFLQKR 

       310        320 
STWIFVWYRL IFGVVILTAL GMGFGT 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10212.1.
PIRS76360.
RefSeqNP_442142.1. NC_000911.1.
YP_005652200.1. NC_017277.1.
YP_007452019.1. NC_020286.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55684. 2 interactions.
STRING1148.sll0210.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10212; BAA10212; BAA10212.
GeneID12253419.
14617695.
952643.
KEGGsyn:sll0210.
syy:SYNGTS_2247.
syz:MYO_122730.
PATRIC23841896. VBISynSp132158_2490.

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAMGASKRS.
OrthoDBEOG6QP13M.
PhylomeDBQ55684.
ProtClustDBPRK00281.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNY3
AccessionPrimary (citable) accession number: Q55684
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families