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Q55673 (MURA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

EC=2.5.1.7
Alternative name(s):
Enoylpyruvate transferase
UDP-N-acetylglucosamine enolpyruvyl transferase
Short name=EPT
Gene names
Name:murA
Synonyms:murZ
Ordered Locus Names:slr0017
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00111.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 438438UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111
PRO_0000178942

Sites

Active site1291Proton donor By similarity

Amino acid modifications

Modified residue12912-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55673 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: C310AB287F2F0F55

FASTA43846,605
        10         20         30         40         50         60 
MLQVATPTAT EETQTVIEIE GRASLKGEVR ISGAKNSALA IMAGTILCSD DCRLSNLPAL 

        70         80         90        100        110        120 
ADIDKMCQIL AAIGVNLERD GDRLVVDSSN VGHGPAPYEL VSQLRASFFV IGPLLSRLGM 

       130        140        150        160        170        180 
TKVPLPGGCA IGTRPVDLHV RGLQAMGADV HIEHGVVNAS IKGHSRRLTG AKIYLDYPSV 

       190        200        210        220        230        240 
GATETILMAA TLAEGETVID NAAREPEIVD LANFCRSMGA QIRGDGSSRI IINGVEKLHS 

       250        260        270        280        290        300 
TDFPIIPDRI EAATFLCAGA ITHSEISLFP VVPDHLASAI AKLREIGPEV AIDAPDRVRL 

       310        320        330        340        350        360 
IPRDLRGTDI ETLPYPGFPT DMQAQFMALL AVSEGNSVVT ETVFENRLQH VAELQRMGAN 

       370        380        390        400        410        420 
IKLKGNAAFI QGVPFLSGAP VMSTDLRASA ALVIAGLAAE GKTIVQGLRH LDRGYEDIEG 

       430 
KLRKLGAKLT RIEQPVTL 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10199.1.
PIRS76347.
RefSeqNP_442129.1. NC_000911.1.
YP_005652187.1. NC_017277.1.
YP_007452006.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55673.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.slr0017.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10199; BAA10199; BAA10199.
GeneID12253404.
14617680.
952795.
KEGGsyn:slr0017.
syy:SYNGTS_2234.
syz:MYO_122580.
PATRIC23841864. VBISynSp132158_2476.

Phylogenomic databases

eggNOGCOG0766.
HOGENOMHOG000075602.
KOK00790.
OMAGYEHIED.
OrthoDBEOG68M4GK.
PhylomeDBQ55673.
ProtClustDBPRK09369.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. SSF55205. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURA_SYNY3
AccessionPrimary (citable) accession number: Q55673
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways