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Q55637 (RNC2_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3 2

EC=3.1.26.3
Alternative name(s):
Ribonuclease III 2
Short name=RNase III 2
Gene names
Name:rnc2
Ordered Locus Names:slr0346
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 244244Ribonuclease 3 2 HAMAP-Rule MF_00104
PRO_0000180464

Regions

Domain11 – 136126RNase III
Domain164 – 23471DRBM

Sites

Active site541 Potential
Active site1251 By similarity
Metal binding501Magnesium By similarity
Metal binding1221Magnesium By similarity
Metal binding1251Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55637 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: E980A4D61185430B

FASTA24427,106
        10         20         30         40         50         60 
MSLLPHRQTQ LKALLRRLGL TDNTPVDWNL VDLALTHASQ SPEQNYQQLE FVGDAVVRLA 

        70         80         90        100        110        120 
SAEVLMKHYP QTSVGEMSAL RAILVSDRTL AGWGELYGLD RFLWITPAVL ADKNGRVSLM 

       130        140        150        160        170        180 
ADSFEALLGA LYLSVGDLSL IRPWLSEHLL AKATEIRQDP ALHNYKEALQ AWTQAHYKCL 

       190        200        210        220        230        240 
PEYRVEPLDQ NLPQQSGFQA TVWLGDQPLG SGSGSSKKSA EQAAAQQAYQ DFIAKEILPM 


PKIN 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10153.1.
PIRS76301.
RefSeqNP_442083.1. NC_000911.1.
YP_005652141.1. NC_017277.1.
YP_007451960.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55637.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55637. 1 interaction.
STRING1148.slr0346.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10153; BAA10153; BAA10153.
GeneID12253354.
14617630.
952695.
KEGGsyn:slr0346.
syy:SYNGTS_2188.
syz:MYO_122080.
PATRIC23841760. VBISynSp132158_2427.

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMAISMEANY.
OrthoDBEOG6T1WVS.
PhylomeDBQ55637.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC2_SYNY3
AccessionPrimary (citable) accession number: Q55637
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families