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Q55630 (SASA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Adaptive-response sensory-kinase SasA

EC=2.7.13.3
Gene names
Name:sasA
Synonyms:sarA
Ordered Locus Names:sll0750
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length383 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs By similarity. HAMAP-Rule MF_01837

Catalytic activity

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. HAMAP-Rule MF_01837

Subunit structure

Interacts with KaiC. Participates in the KaiABC complex, whose core is composed of a KaiC homohexamer, a KaiB dimer and two KaiA dimers By similarity.

Sequence similarities

Contains 1 histidine kinase domain.

Ontologies

Keywords
   Biological processBiological rhythms
Two-component regulatory system
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcircadian rhythm

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentmembrane

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphorelay sensor kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 383383Adaptive-response sensory-kinase SasA HAMAP-Rule MF_01837
PRO_0000074874

Regions

Domain161 – 383223Histidine kinase

Amino acid modifications

Modified residue1641Phosphohistidine; by autocatalysis By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55630 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 395621F5C4BF42F1

FASTA38343,436
        10         20         30         40         50         60 
MSSSSELGNA SSVPLQFLLF IDDRPNSQDS VQEIGQCLTN LLDGHSHDLQ ILQISKHPHL 

        70         80         90        100        110        120 
VEHFRLVATP SLIKLQPEPR QVLAGSNIIQ QLQKWWPRWQ QELAMDPNPE DTGQSPSCPR 

       130        140        150        160        170        180 
EISSVGYSGE LMKMSDELFL LKKDKEELLQ QIQFKDQILA MLAHDLRSPL TAASIAVDTL 

       190        200        210        220        230        240 
ELLQHKPIEE QKPALRSQLL YQARKQFKIM DRLIEDILQA SKNLNSQFQV HGRPLAIADL 

       250        260        270        280        290        300 
CQEVLELYQA KFSKKNLTIT YDIPKDLPNV FADEELIRQV IANLLDNAIK YTPAHGSITV 

       310        320        330        340        350        360 
GALHRTTQKV QVSITDNGPG IPNSKQETIF EGHFRLQRDE QTDGYGLGLS LCRKIIQAHY 

       370        380 
GQIWVDSRPK QGSSFHFTLP VYR 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10143.1.
PIRS76291.
RefSeqNP_442073.1. NC_000911.1.
YP_005652131.1. NC_017277.1.
YP_007451950.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55630.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55630. 9 interactions.
STRING1148.sll0750.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10143; BAA10143; BAA10143.
GeneID952700.
KEGGsyn:sll0750.
syy:SYNGTS_2178.
syz:MYO_121980.
PATRIC23841738. VBISynSp132158_2416.

Phylogenomic databases

eggNOGCOG0642.
HOGENOMHOG000233315.
KOK08479.
OMAHFTLPVY.
OrthoDBEOG6G4VQG.
PhylomeDBQ55630.

Family and domain databases

Gene3D1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
3.40.30.10. 1 hit.
HAMAPMF_01837. Kinase_SasA.
InterProIPR003661. EnvZ-like_dim/P.
IPR003594. HATPase_ATP-bd.
IPR011649. KaiB_domain.
IPR023527. Kinase_SasA.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF07689. KaiB. 1 hit.
[Graphical view]
PRINTSPR00344. BCTRLSENSOR.
SMARTSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMSSF47384. SSF47384. 1 hit.
SSF52833. SSF52833. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSASA_SYNY3
AccessionPrimary (citable) accession number: Q55630
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families