Q555L8 (Y4695_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SH3 and FCH domain-containing protein DDB_G0274695

Gene names

ORF Names:

DDB_G0274695

Organism

Dictyostelium discoideum (Slime mold) [Reference proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 FCH domain. Contains 1 SH3 domain.

Ontologies

Keywords
Domain	Coiled coil SH3 domain
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	SH3 and FCH domain-containing protein DDB_G0274695		PRO_0000384437
Regions
	Domain	3 – 82	80	FCH
	Domain	332 – 389	58	SH3
	Coiled coil	119 – 192	74	Potential
	Compositional bias	273 – 276	4	Poly-Pro
Experimental info
	Sequence conflict	204	1	S → F in AAM44380. Ref.1
	Sequence conflict	235	1	T → P in AAM44380. Ref.1
	Sequence conflict	242	1	T → P in AAM44380. Ref.1
	Sequence conflict	335	1	K → N in AAM44380. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q555L8 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 8E01112F246EDA86	FASTA	389	44,221
	10 20 30 40 50 60 MSEQFKDNFW GPNGFETIEK RMNQGTESTR LFLLFLKERA AIEENYSKSL QKLLKSTSQL 70 80 90 100 110 120 IEYGTLRDAW YGVRGEAESL VRVHHELGQK IEKDIVAPFS KFKSEQKKVK KNFLYDAYKL 130 140 150 160 170 180 NKERKDMESS ITKTRAKYDD YSKQAETIAI TMETAKNTKT AAEVGKIQSK LQKIQRDASS 190 200 210 220 230 240 AEQDYRDSVN KLSMYQPTWE DKVSSNYHTL QLTEEERIDY IKVQLEKYVG AIKSTVPDTE 250 260 270 280 290 300 TTNRNLVNVI TQIDKLEDIH CFVRESRTGT EKPPPPQFIS FGGKSSSDYI QNKASYSAPL 310 320 330 340 350 360 TSSVSSNSLT SSYNSATTTP TPAPRSTPIN LSKKKQAKAL YDYVGSDATE LDFFAGDIIT 370 380 ILDEDESGWF RGELGDRIGL YPSNYCEPI

References

[1]	"Sequence and analysis of chromosome 2 of Dictyostelium discoideum." Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A. Nature 418:79-85(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC123513 Genomic DNA. Translation: AAM44380.1. AAFI02000012 Genomic DNA. Translation: EAL70240.1.
RefSeq	XP_644048.1. XM_638956.1.
3D structure databases
HSSP	HSSP built from PDB template 2A37 based on UniProtKB Q08012.
ProteinModelPortal	Q555L8.
ModBase	Search...
Protein-protein interaction databases
STRING	44689.DDBDRAFT_0203245.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0266841; DDB0266841; DDB_G0274695.
GeneID	8619478.
KEGG	ddi:DDB_G0274695.
Organism-specific databases
dictyBase	DDB_G0274695.
Phylogenomic databases
eggNOG	NOG303711.
OMA	WLAVMTE.
Family and domain databases
InterPro	IPR001060. FCH_dom. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00611. FCH. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00452. SH3DOMAIN.
SMART	SM00055. FCH. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50044. SH3. 1 hit.
PROSITE	PS50133. FCH. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y4695_DICDI

Accession

Primary (citable) accession number: Q555L8
Secondary accession number(s): Q8MML2, Q8T177

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 24, 2005
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)