Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

SH3 and F-BAR domain-containing protein DDB_G0274695

Gene

DDB_G0274695

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • microtubule binding Source: dictyBase

GO - Biological processi

  • actin filament polymerization Source: dictyBase
  • chemotaxis to cAMP Source: dictyBase
  • vesicle organization Source: dictyBase

Enzyme and pathway databases

ReactomeiR-DDI-194840. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Recommended name:
SH3 and F-BAR domain-containing protein DDB_G0274695
Gene namesi
ORF Names:DDB_G0274695
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0274695. slp.

Subcellular locationi

GO - Cellular componenti

  • perinuclear region of cytoplasm Source: dictyBase
  • vesicle Source: dictyBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003844371 – 389SH3 and F-BAR domain-containing protein DDB_G0274695Add BLAST389

Proteomic databases

PaxDbiQ555L8.

Interactioni

GO - Molecular functioni

  • microtubule binding Source: dictyBase

Protein-protein interaction databases

STRINGi44689.DDB0266841.

Structurei

3D structure databases

ProteinModelPortaliQ555L8.
SMRiQ555L8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 258F-BARPROSITE-ProRule annotationAdd BLAST256
Domaini332 – 389SH3PROSITE-ProRule annotationAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili119 – 192Sequence analysisAdd BLAST74

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi273 – 276Poly-Pro4

Keywords - Domaini

Coiled coil, SH3 domain

Phylogenomic databases

eggNOGiENOG410IU8N. Eukaryota.
ENOG410XR8X. LUCA.
InParanoidiQ555L8.
OMAiFQTIYHT.
PhylomeDBiQ555L8.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR031160. F_BAR.
IPR001060. FCH_dom.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
PRINTSiPR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS51741. F_BAR. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q555L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQFKDNFW GPNGFETIEK RMNQGTESTR LFLLFLKERA AIEENYSKSL
60 70 80 90 100
QKLLKSTSQL IEYGTLRDAW YGVRGEAESL VRVHHELGQK IEKDIVAPFS
110 120 130 140 150
KFKSEQKKVK KNFLYDAYKL NKERKDMESS ITKTRAKYDD YSKQAETIAI
160 170 180 190 200
TMETAKNTKT AAEVGKIQSK LQKIQRDASS AEQDYRDSVN KLSMYQPTWE
210 220 230 240 250
DKVSSNYHTL QLTEEERIDY IKVQLEKYVG AIKSTVPDTE TTNRNLVNVI
260 270 280 290 300
TQIDKLEDIH CFVRESRTGT EKPPPPQFIS FGGKSSSDYI QNKASYSAPL
310 320 330 340 350
TSSVSSNSLT SSYNSATTTP TPAPRSTPIN LSKKKQAKAL YDYVGSDATE
360 370 380
LDFFAGDIIT ILDEDESGWF RGELGDRIGL YPSNYCEPI
Length:389
Mass (Da):44,221
Last modified:May 24, 2005 - v1
Checksum:i8E01112F246EDA86
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti204S → F in AAM44380 (PubMed:12097910).Curated1
Sequence conflicti235T → P in AAM44380 (PubMed:12097910).Curated1
Sequence conflicti242T → P in AAM44380 (PubMed:12097910).Curated1
Sequence conflicti335K → N in AAM44380 (PubMed:12097910).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123513 Genomic DNA. Translation: AAM44380.1.
AAFI02000012 Genomic DNA. Translation: EAL70240.1.
RefSeqiXP_644048.1. XM_638956.1.

Genome annotation databases

EnsemblProtistsiEAL70240; EAL70240; DDB_G0274695.
GeneIDi8619478.
KEGGiddi:DDB_G0274695.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123513 Genomic DNA. Translation: AAM44380.1.
AAFI02000012 Genomic DNA. Translation: EAL70240.1.
RefSeqiXP_644048.1. XM_638956.1.

3D structure databases

ProteinModelPortaliQ555L8.
SMRiQ555L8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0266841.

Proteomic databases

PaxDbiQ555L8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL70240; EAL70240; DDB_G0274695.
GeneIDi8619478.
KEGGiddi:DDB_G0274695.

Organism-specific databases

dictyBaseiDDB_G0274695. slp.

Phylogenomic databases

eggNOGiENOG410IU8N. Eukaryota.
ENOG410XR8X. LUCA.
InParanoidiQ555L8.
OMAiFQTIYHT.
PhylomeDBiQ555L8.

Enzyme and pathway databases

ReactomeiR-DDI-194840. Rho GTPase cycle.

Miscellaneous databases

PROiPR:Q555L8.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR031160. F_BAR.
IPR001060. FCH_dom.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
PRINTSiPR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS51741. F_BAR. 1 hit.
PS50002. SH3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiY4695_DICDI
AccessioniPrimary (citable) accession number: Q555L8
Secondary accession number(s): Q8MML2, Q8T177
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 24, 2005
Last modified: May 10, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.