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Q55585 (GABD_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable succinate-semialdehyde dehydrogenase [NADP(+)]

Short name=SSDH
EC=1.2.1.79
Gene names
Name:gabD
Ordered Locus Names:slr0370
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADP+ dependent oxidation of succinate semialdehyde to succinate By similarity.

Catalytic activity

Succinate semialdehyde + NADP+ + H2O = succinate + NADPH.

Pathway

Amino-acid degradation; 4-aminobutanoate degradation.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Probable succinate-semialdehyde dehydrogenase [NADP(+)]
PRO_0000056574

Regions

Nucleotide binding130 – 1312NADP By similarity
Nucleotide binding154 – 1574NADP By similarity
Nucleotide binding206 – 2072NADP By similarity

Sites

Active site2281Proton acceptor By similarity
Active site2621Nucleophile By similarity
Binding site2291NADP; via carbonyl oxygen By similarity
Binding site3591NADP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55585 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 8785B19AEF376317

FASTA45448,749
        10         20         30         40         50         60 
MAIATINPAT GQTVQTFIAH SQVEVNAKLD LAQETFQSFR HLPFAQRGQW LRKAADILEQ 

        70         80         90        100        110        120 
RRDEWAALMT LEMGKSIPQA IAEVNKCALV CRFYADKAEE YLADEVVTTD ASQSFIAYQP 

       130        140        150        160        170        180 
LGVILAVMPW NFPFWQVFRF AAPALMAGNV GLLKHASNVP QCALAIAEIF QTAGFPEGAF 

       190        200        210        220        230        240 
QTLLIGGKVA SELMADDRIQ AGTLTGSEPA GASFASAAAG QIKKTVLELG GSDPFIVLED 

       250        260        270        280        290        300 
ADLDQALKVA VPARMQNNGQ SCIAAKRFIV QASVAEEFFQ RLTKAFQALK VGDPSLSTTD 

       310        320        330        340        350        360 
IGPLATPDIL ADIVAQVEQT IAAGAHCRCG GQALDQPGNY YPPTLLTDVP PNAPTYRQEF 

       370        380        390        400        410        420 
FGPVALGFTV DNLEEAIALA NDIPFGLGAS AWTTNPENQQ KLIRGIEAGA VFINGMTKSD 

       430        440        450 
PRIPFGGIKR SGFGRELGRM GILEFVNAKT VWIA 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10090.1.
PIRS76112.
RefSeqNP_442020.1. NC_000911.1.
YP_005652079.1. NC_017277.1.
YP_007451899.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55585.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55585. 2 interactions.
STRING1148.slr0370.

Proteomic databases

PaxDbQ55585.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10090; BAA10090; BAA10090.
GeneID12253291.
14617568.
952057.
KEGGsyn:slr0370.
syy:SYNGTS_2126.
syz:MYO_121460.
PATRIC23841616. VBISynSp132158_2356.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271513.
KOK00135.
OMARLNNTGQ.
OrthoDBEOG6BS8QW.

Enzyme and pathway databases

UniPathwayUPA00733.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGABD_SYNY3
AccessionPrimary (citable) accession number: Q55585
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways