Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q55585

- GABD_SYNY3

UniProt

Q55585 - GABD_SYNY3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable succinate-semialdehyde dehydrogenase [NADP(+)]

Gene

gabD

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the NADP+ dependent oxidation of succinate semialdehyde to succinate.By similarity

Catalytic activityi

Succinate semialdehyde + NADP+ + H2O = succinate + NADPH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei228 – 2281Proton acceptorBy similarity
Binding sitei229 – 2291NADP; via carbonyl oxygenBy similarity
Active sitei262 – 2621NucleophileBy similarity
Binding sitei359 – 3591NADPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi130 – 1312NADPBy similarity
Nucleotide bindingi154 – 1574NADPBy similarity
Nucleotide bindingi206 – 2072NADPBy similarity

GO - Molecular functioni

  1. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00733.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable succinate-semialdehyde dehydrogenase [NADP(+)] (EC:1.2.1.79)
Short name:
SSDH
Gene namesi
Name:gabD
Ordered Locus Names:slr0370
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 454454Probable succinate-semialdehyde dehydrogenase [NADP(+)]PRO_0000056574Add
BLAST

Proteomic databases

PaxDbiQ55585.

Interactioni

Protein-protein interaction databases

IntActiQ55585. 2 interactions.
STRINGi1148.slr0370.

Structurei

3D structure databases

ProteinModelPortaliQ55585.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271513.
InParanoidiQ55585.
KOiK00135.
OMAiSHIIENQ.
OrthoDBiEOG6BS8QW.
PhylomeDBiQ55585.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.

Sequencei

Sequence statusi: Complete.

Q55585-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIATINPAT GQTVQTFIAH SQVEVNAKLD LAQETFQSFR HLPFAQRGQW
60 70 80 90 100
LRKAADILEQ RRDEWAALMT LEMGKSIPQA IAEVNKCALV CRFYADKAEE
110 120 130 140 150
YLADEVVTTD ASQSFIAYQP LGVILAVMPW NFPFWQVFRF AAPALMAGNV
160 170 180 190 200
GLLKHASNVP QCALAIAEIF QTAGFPEGAF QTLLIGGKVA SELMADDRIQ
210 220 230 240 250
AGTLTGSEPA GASFASAAAG QIKKTVLELG GSDPFIVLED ADLDQALKVA
260 270 280 290 300
VPARMQNNGQ SCIAAKRFIV QASVAEEFFQ RLTKAFQALK VGDPSLSTTD
310 320 330 340 350
IGPLATPDIL ADIVAQVEQT IAAGAHCRCG GQALDQPGNY YPPTLLTDVP
360 370 380 390 400
PNAPTYRQEF FGPVALGFTV DNLEEAIALA NDIPFGLGAS AWTTNPENQQ
410 420 430 440 450
KLIRGIEAGA VFINGMTKSD PRIPFGGIKR SGFGRELGRM GILEFVNAKT

VWIA
Length:454
Mass (Da):48,749
Last modified:November 1, 1996 - v1
Checksum:i8785B19AEF376317
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA10090.1.
PIRiS76112.
RefSeqiNP_442020.1. NC_000911.1.
YP_005652079.1. NC_017277.1.
YP_007451899.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA10090; BAA10090; BAA10090.
GeneIDi952057.
KEGGisyn:slr0370.
syy:SYNGTS_2126.
syz:MYO_121460.
PATRICi23841616. VBISynSp132158_2356.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA10090.1 .
PIRi S76112.
RefSeqi NP_442020.1. NC_000911.1.
YP_005652079.1. NC_017277.1.
YP_007451899.1. NC_020286.1.

3D structure databases

ProteinModelPortali Q55585.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q55585. 2 interactions.
STRINGi 1148.slr0370.

Proteomic databases

PaxDbi Q55585.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA10090 ; BAA10090 ; BAA10090 .
GeneIDi 952057.
KEGGi syn:slr0370.
syy:SYNGTS_2126.
syz:MYO_121460.
PATRICi 23841616. VBISynSp132158_2356.

Phylogenomic databases

eggNOGi COG1012.
HOGENOMi HOG000271513.
InParanoidi Q55585.
KOi K00135.
OMAi SHIIENQ.
OrthoDBi EOG6BS8QW.
PhylomeDBi Q55585.

Enzyme and pathway databases

UniPathwayi UPA00733 .

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiGABD_SYNY3
AccessioniPrimary (citable) accession number: Q55585
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3