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Protein

Acyl-CoA synthetase short-chain family member B, mitochondrial

Gene

aslB

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activates acetate so that it can be used for lipid synthesis or for energy generation.By similarity

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl-CoA synthetase short-chain family member B, mitochondrial (EC:6.2.1.1)
Gene namesi
Name:aslB
ORF Names:DDB_G0274939
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0274939. aslB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 688Acyl-CoA synthetase short-chain family member B, mitochondrialPRO_0000327600
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

PaxDbiQ554Z5.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0231689.

Structurei

3D structure databases

ProteinModelPortaliQ554Z5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1175. Eukaryota.
COG0365. LUCA.
InParanoidiQ554Z5.
KOiK01908.
OMAiLPVKHGS.
PhylomeDBiQ554Z5.

Family and domain databases

InterProiIPR032387. ACAS_N.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF16177. ACAS_N. 1 hit.
PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q554Z5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSNGLSKLI KSKIASTSII TTKNNYSISK LSFSSTSILL NKKYKLSEPF
60 70 80 90 100
NYEQDCEYAL KEPIQFWDEV ASKYVHWNKR YEKVYSGDEY NPEWFKGGVL
110 120 130 140 150
NACYNALDVH AKDPITKNRI AIIHETPSKN NTNKLTYGEL WDEVCIFARG
160 170 180 190 200
LHNLGVEKGD RVVIYMPMIN QALIAMLACA RLGATHSVVF GGFASPQLAQ
210 220 230 240 250
RIEHFKPKVV ISANFGVEGH KINCYTPLLS KALELSSHKP NHTIVYNRLD
260 270 280 290 300
VKLDAGEVLP PRVEGSLDWS ELIKNIAPYR DYALVDSTHP LYILYTSGTT
310 320 330 340 350
GMPKGVVRDT GGYSVALNYS IRNCYGMKSG DTFFAGSDVG WVVGHTLSVY
360 370 380 390 400
GPLMVGLTSI IFEGKPTVPD ASTYWKLIEK HRVNALFSAP TAIRAIHRDD
410 420 430 440 450
ADGKLASKCD LSSLRSIWLG GERLDSSTFN FLRNITNNKP ILDNYWNTES
460 470 480 490 500
GSPLITNPSC QVPIKANATG KPMPGYQFHV LSPTSERLGA DKIGEVCIKL
510 520 530 540 550
PVAPGFTNTL YLNPEGYKNA YLNEYPGYLR TADSGYYDEN GYYHIISRVD
560 570 580 590 600
DIINVSGHRL STGSIEEILV KHPKIVECAV IGVHDELKGE IPFGLVVLKP
610 620 630 640 650
QYKDCAEEVE NELIKEVREN IGPVATFKKV LSVNRLPKTR SGKILRNILR
660 670 680
KMYNKEEYTV PPTIEDMEVL KEIDIEFEKY KLSHPPKK
Length:688
Mass (Da):77,120
Last modified:May 24, 2005 - v1
Checksum:iB79E17A745EC4E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL70362.1.
RefSeqiXP_644178.1. XM_639086.1.

Genome annotation databases

EnsemblProtistsiDDB0231689; DDB0231689; DDB_G0274939.
GeneIDi8619607.
KEGGiddi:DDB_G0274939.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000012 Genomic DNA. Translation: EAL70362.1.
RefSeqiXP_644178.1. XM_639086.1.

3D structure databases

ProteinModelPortaliQ554Z5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0231689.

Proteomic databases

PaxDbiQ554Z5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0231689; DDB0231689; DDB_G0274939.
GeneIDi8619607.
KEGGiddi:DDB_G0274939.

Organism-specific databases

dictyBaseiDDB_G0274939. aslB.

Phylogenomic databases

eggNOGiKOG1175. Eukaryota.
COG0365. LUCA.
InParanoidiQ554Z5.
KOiK01908.
OMAiLPVKHGS.
PhylomeDBiQ554Z5.

Miscellaneous databases

PROiQ554Z5.

Family and domain databases

InterProiIPR032387. ACAS_N.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF16177. ACAS_N. 1 hit.
PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACSB_DICDI
AccessioniPrimary (citable) accession number: Q554Z5
Secondary accession number(s): Q869S4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: December 9, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.