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Q55486 (SYR_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:sll0502
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length584 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 584584Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151627

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q55486 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 89602A1A5A3BD85B

FASTA58465,213
        10         20         30         40         50         60 
MVSILTQLND HFAQALEGQF PSDVTLPTPL VVPASNPKFG DFQCNIALPL AKQLGQPPRA 

        70         80         90        100        110        120 
IAMEIVDKVN LSEICEPLTI AGPGFINIKL LPDYLGEQLI KLQQNQQLGV SLVKGEERIV 

       130        140        150        160        170        180 
VDFSSPNIAK EMHVGHLRST IIGDCLARVL EFRGYDVLRL NHVGDWGTQF GMLITYLKEV 

       190        200        210        220        230        240 
YPEALVTADA LDIGDLVTFY KQAKQRFDQD EQFRETSRQA VVALQAGDAK SIKAWQLLCE 

       250        260        270        280        290        300 
QSRREFQLIY DCLDITIEER GESFYNPFLP GVVELLQEKD LLVEDNGAQC VFLDGFTNKD 

       310        320        330        340        350        360 
GDRLPLIVQK SDGGYNYATT DLAALNYRLN TDGAEKIIYV TDAGQANHFA QFFQVAEKAG 

       370        380        390        400        410        420 
ILTDPTQVVH VPFGLVKGED GKKLKTRAGD TIRLKDLLTE AVTRARQDLE TRLTAEERSE 

       430        440        450        460        470        480 
TEEFKTEVAQ RVGIGAVKYA DLSQNRTSDY VFSFDKMLAL QGNTAPYMLY AYARIQSISR 

       490        500        510        520        530        540 
EGGIDFAQMD SGEIVLTEPT ELVLAKNLLQ FADVIETVEI SLLPNRLCDY LYELSKVFNR 

       550        560        570        580 
FYENCPVLKA SDPQRGSRLL LCDLTARTLK LGLSLLGIPV LDRM 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10833.1.
PIRS75986.
RefSeqNP_442762.1. NC_000911.1.
YP_005652823.1. NC_017277.1.
YP_007452638.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ55486.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ55486. 3 interactions.
STRING1148.sll0502.

Proteomic databases

PaxDbQ55486.
PRIDEQ55486.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10833; BAA10833; BAA10833.
GeneID12255097.
14618320.
953297.
KEGGsyn:sll0502.
syy:SYNGTS_2870.
syz:MYO_128960.
PATRIC23843278. VBISynSp132158_3177.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
PhylomeDBQ55486.
ProtClustDBPRK01611.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNY3
AccessionPrimary (citable) accession number: Q55486
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries