Q55467 (CHLM_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Magnesium-protoporphyrin O-methyltransferase
EC=2.1.1.11

Alternative name(s):
Magnesium-protoporphyrin IX methyltransferase

Gene names

Name:	chlM
Ordered Locus Names:	slr0525

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor.
Catalytic activity	S-adenosyl-L-methionine + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13-methyl ester.
Pathway	Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).
Sequence similarities	Belongs to the methyltransferase superfamily.

Ontologies

Keywords
Biological process	Chlorophyll biosynthesis Photosynthesis
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	light-independent chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway photosynthesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	magnesium protoporphyrin IX methyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	Magnesium-protoporphyrin O-methyltransferase		PRO_0000204421
Experimental info
	Sequence conflict	190	1	A → V in AAA85380. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q55467 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 166D72CF3DD178A0	FASTA	230	25,081
	10 20 30 40 50 60 MTNAALDDKT IVRDYFNSTG FDRWRRIYGD GQVNFVQKDI RVGHQQTVDS VVAWLVADGN 70 80 90 100 110 120 LPGLLVCDAG CGVGSLSIPL AQAGALVYGS DISEKMVGEA QQKAQEVLAY GNQPTFMTQD 130 140 150 160 170 180 LAQLGGKYDT VICLDVLIHY PTEEASAMIS HLASLADRRL ILSFAPKTLG LTVLKKIGGL 190 200 210 220 230 FPGPSKTTRA YQHKEADIRK ILGDNGFSIA RTGMTSTRFY YSRILEAVRS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of the chlorophyll biosynthesis gene chlM from Synechocystis PCC 6803 by complementation of a bacteriochlorophyll biosynthesis mutant of Rhodobacter capsulatus." Smith C.A., Suzuki J.Y., Bauer C.E. Plant Mol. Biol. 30:1307-1314(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[3]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L47126 Genomic DNA. Translation: AAA85380.1. BA000022 Genomic DNA. Translation: BAA10812.1.
PIR	S71781.
RefSeq	NP_442741.1. NC_000911.1. YP_005652802.1. NC_017277.1. YP_007452617.1. NC_020286.1.
3D structure databases
ProteinModelPortal	Q55467.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q55467. 4 interactions.
STRING	1148.slr0525.
Proteomic databases
PaxDb	Q55467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA10812; BAA10812; BAA10812.
GeneID	12254996. 14618299. 952048.
KEGG	syn:slr0525. syy:SYNGTS_2849.
PATRIC	23843234. VBISynSp132158_3155.
Phylogenomic databases
eggNOG	COG2227.
HOGENOM	HOG000154343.
KO	K03428.
OMA	LDVFIHY.
ProtClustDB	PRK07580.
Enzyme and pathway databases
SABIO-RK	Q55467.
UniPathway	UPA00670.
Family and domain databases
InterPro	IPR010251. Mg_prot_MeTrfase. IPR010940. Mg_prot_MeTrfase_C. [Graphical view]
Pfam	PF07109. Mg-por_mtran_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR02021. BchM-ChlM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CHLM_SYNY3

Accession

Primary (citable) accession number: Q55467
Secondary accession number(s): Q55344

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 14, 2001
Last sequence update:	November 1, 1996
Last modified:	May 29, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program