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Protein

HTH-type transcriptional activator CmpR

Gene

cmpR

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR-cmpA intergenic region.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi21 – 4020H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator CmpR
Gene namesi
Name:cmpR
Ordered Locus Names:sll0030
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304HTH-type transcriptional activator CmpRPRO_0000341943Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ55459.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6161HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000233518.
InParanoidiQ55459.
OMAiVSKLIIQ.
OrthoDBiEOG67X1QR.
PhylomeDBiQ55459.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55459-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNATLHQFE VFAAIARTGS FTKAAEELFL TQPTVSQQMK QLTKAIGVPL
60 70 80 90 100
YEQIGRKIYL TEAGQAVLDA SKNITSCLDQ LQEVIADLQG LKKGNLRLAT
110 120 130 140 150
ITTGKYFVPR LLGEFRQQYP GISISLQIGN RQQILERLAN NLDDLYFLGK
160 170 180 190 200
PPSNLDINIR HFLENPLVVI ASRQHPLVKE KKISLERLVN EPLIMRESGS
210 220 230 240 250
GTRMAVEEFF SENRLKMNVE MEISSNEAIK QAVYGGLGIS ILSLYSLALE
260 270 280 290 300
GINGPLAVLD VEGFPLQKHW YIIYQKSKQL SIVAQTFLDY LFAHDEAVSI

AQIF
Length:304
Mass (Da):34,099
Last modified:November 1, 1996 - v1
Checksum:i7964D82BC3D8A9BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10802.1.
PIRiS75955.

Genome annotation databases

EnsemblBacteriaiBAA10802; BAA10802; BAA10802.
KEGGisyn:sll0030.
PATRICi23843210. VBISynSp132158_3143.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10802.1.
PIRiS75955.

3D structure databases

ProteinModelPortaliQ55459.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10802; BAA10802; BAA10802.
KEGGisyn:sll0030.
PATRICi23843210. VBISynSp132158_3143.

Phylogenomic databases

HOGENOMiHOG000233518.
InParanoidiQ55459.
OMAiVSKLIIQ.
OrthoDBiEOG67X1QR.
PhylomeDBiQ55459.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.
  2. "Involvement of a CbbR homolog in low CO2-induced activation of the bicarbonate transporter operon in cyanobacteria."
    Omata T., Gohta S., Takahashi Y., Harano Y., Maeda S.
    J. Bacteriol. 183:1891-1898(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DNA-BINDING.

Entry informationi

Entry nameiCMPR_SYNY3
AccessioniPrimary (citable) accession number: Q55459
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.