Reviewed, UniProtKB/Swiss-Prot Q55459 (CMPR_SYNY3)

Names and origin

Protein names

Recommended name:
    HTH-type transcriptional activator cmpR

Gene names

Name:	cmpR
Ordered Locus Names:	sll0030

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR-cmpA intergenic region. Ref.2
Subcellular location	Cytoplasm Potential.
Sequence similarities	Contains 1 HTH lysR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Cytoplasm
Ligand	DNA-binding
Molecular function	Activator
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 304	304	HTH-type transcriptional activator cmpR		PRO_0000341943
Regions
	Domain	1 – 61	61	HTH lysR-type
	DNA binding	21 – 40	20	H-T-H motif By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q55459-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 7964D82BC3D8A9BF	FASTA	304	34,099
	10 20 30 40 50 60 MKNATLHQFE VFAAIARTGS FTKAAEELFL TQPTVSQQMK QLTKAIGVPL YEQIGRKIYL 70 80 90 100 110 120 TEAGQAVLDA SKNITSCLDQ LQEVIADLQG LKKGNLRLAT ITTGKYFVPR LLGEFRQQYP 130 140 150 160 170 180 GISISLQIGN RQQILERLAN NLDDLYFLGK PPSNLDINIR HFLENPLVVI ASRQHPLVKE 190 200 210 220 230 240 KKISLERLVN EPLIMRESGS GTRMAVEEFF SENRLKMNVE MEISSNEAIK QAVYGGLGIS 250 260 270 280 290 300 ILSLYSLALE GINGPLAVLD VEGFPLQKHW YIIYQKSKQL SIVAQTFLDY LFAHDEAVSI AQIF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Involvement of a CbbR homolog in low CO2-induced activation of the bicarbonate transporter operon in cyanobacteria." Omata T., Gohta S., Takahashi Y., Harano Y., Maeda S. J. Bacteriol. 183:1891-1898(2001) [PubMed: 11222586] [Abstract] Cited for: FUNCTION, DNA-BINDING.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA10802.1.
PIR	S75955.
RefSeq	NP_442731.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q55459.
Genome annotation databases
GeneID	953295.
GenomeReviews	Gene locus sll0030 in contig BA000022_GR.
KEGG	syn:sll0030.
NMPDR	fig|1148.1.peg.2832.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q55459.
OMA	NDSEMAI
Enzyme and pathway databases
BioCyc	SSP1148:SLL0030-MON.
Family and domain databases
InterPro	IPR000847. HTH_LysR. IPR005119. LysR_subst_bd. IPR011991. Wing_hlx_DNA_bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit. [Graphical view]
PRINTS	PR00039. HTHLYSR.
PROSITE	PS50931. HTH_LYSR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CMPR_SYNY3

Accession

Primary (citable) accession number: Q55459

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	November 1, 1996
Last modified:	November 3, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)