Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NAD(P)H-quinone oxidoreductase chain 5

Gene

ndhF

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activityi

NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD, NADP, Plastoquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H-quinone oxidoreductase chain 5 (EC:1.6.5.-)
Alternative name(s):
NAD(P)H dehydrogenase I, chain 5
NDH-1, chain 5
Gene namesi
Name:ndhF
Ordered Locus Names:slr0844
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei144 – 164HelicalSequence analysisAdd BLAST21
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Transmembranei219 – 239HelicalSequence analysisAdd BLAST21
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Transmembranei327 – 347HelicalSequence analysisAdd BLAST21
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Transmembranei420 – 440HelicalSequence analysisAdd BLAST21
Transmembranei509 – 529HelicalSequence analysisAdd BLAST21
Transmembranei558 – 578HelicalSequence analysisAdd BLAST21
Transmembranei660 – 680HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001182101 – 681NAD(P)H-quinone oxidoreductase chain 5Add BLAST681

Keywords - PTMi

Quinone

Proteomic databases

PRIDEiQ55429.

Interactioni

Protein-protein interaction databases

IntActiQ55429. 9 interactors.
STRINGi1148.SYNGTS_2568.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000100569.
InParanoidiQ55429.
KOiK05577.
OMAiQFYALIV.
PhylomeDBiQ55429.

Family and domain databases

InterProiView protein in InterPro
IPR002128. NADH_UbQ_OxRdtase_chlpt_su5_C.
IPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
IPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
PfamiView protein in Pfam
PF01010. Proton_antipo_C. 1 hit.
PF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.

Sequencei

Sequence statusi: Complete.

Q55429-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELLYQLAWL IPVLPLFGAT VVGIGLISFN QATNKLRQIN AVFIISCLGA
60 70 80 90 100
ALVMSGALLW DQIQGHASYA QMIEWASAGS FHLEMGYVID HLSALMLVIV
110 120 130 140 150
TSVALLVMIY TDGYMAHDPG YVRFYAYLSL FASSMLGLVI SPNLVQVYIF
160 170 180 190 200
WELVGMCSYL LIGFWYDRKA AADACQKAFV TNRVGDFGLL LGILGLYWAT
210 220 230 240 250
GSFDFGTIGE RLEGLVSSGV LSGAIAAILA ILVFLGPVAK SAQFPLHVWL
260 270 280 290 300
PDAMEGPTPI SALIHAATMV AAGVFLVARM YPVFEPIPVV MNTIAFTGCF
310 320 330 340 350
TAFLGATIAL TQNDIKKGLA YSTISQLGYM VMAMGIGAYS AGLFHLMTHA
360 370 380 390 400
YFKAMLFLCS GSVIHGMEGV VGHDPILAQD MRIMGGLRKY MPITATCFLI
410 420 430 440 450
GTLAICGIPP FAGFWSKDEI LGLAFQANPL LWFVGWATAG MTAFYMFRMY
460 470 480 490 500
FMTFEGGFRG NDQEAKDGVL QFYGLLPNFG PGAMNVKELD HEAGHDDHGH
510 520 530 540 550
SSEPHESPLT MTFPLMALAV PSVLIGLLGR PWANQFEAFI HAPGEVVEHA
560 570 580 590 600
AEFEWGEFYV MAGNSIGIAL IGITVASLMY WQHKFDPKVL AEKFPSLYQL
610 620 630 640 650
SLNKWYFDDL YDKLFVQGSR RVARQIMEVD YKVIDGAVNL TGLVTLVSGE
660 670 680
GLKYLENGRA QFYALIVFGA VLGFVIVFSL T
Length:681
Mass (Da):74,400
Last modified:November 1, 1997 - v1
Checksum:iD110C883B722FDAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10530.1.
PIRiS75795.

Genome annotation databases

EnsemblBacteriaiBAA10530; BAA10530; BAA10530.
KEGGisyn:slr0844.

Similar proteinsi

Entry informationi

Entry nameiNU5C_SYNY3
AccessioniPrimary (citable) accession number: Q55429
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 5, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names