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Q553B6

- NMT_DICDI

UniProt

Q553B6 - NMT_DICDI

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Protein

Glycylpeptide N-tetradecanoyltransferase

Gene
nmt, DDB_G0275863
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins By similarity.

Catalytic activityi

Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.

GO - Molecular functioni

  1. glycylpeptide N-tetradecanoyltransferase activity Source: dictyBase

GO - Biological processi

  1. N-terminal protein myristoylation Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glycylpeptide N-tetradecanoyltransferase (EC:2.3.1.97)
Alternative name(s):
Myristoyl-CoA:protein N-myristoyltransferase
Short name:
NMT
Peptide N-myristoyltransferase
Gene namesi
Name:nmt
ORF Names:DDB_G0275863
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 2, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0275863. nmt.

Subcellular locationi

Cytoplasm Reviewed prediction

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 413413Glycylpeptide N-tetradecanoyltransferasePRO_0000331294Add
BLAST

Proteomic databases

PRIDEiQ553B6.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0217694.

Family & Domainsi

Sequence similaritiesi

Belongs to the NMT family.

Phylogenomic databases

eggNOGiCOG5092.
KOiK00671.
OMAiQRTIKLY.
PhylomeDBiQ553B6.

Family and domain databases

Gene3Di3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000903. MyristoylCoA_TrFase.
IPR022677. MyristoylCoA_TrFase_C.
IPR022678. MyristoylCoA_TrFase_CS.
IPR022676. MyristoylCoA_TrFase_N.
[Graphical view]
PANTHERiPTHR11377. PTHR11377. 1 hit.
PfamiPF01233. NMT. 1 hit.
PF02799. NMT_C. 1 hit.
[Graphical view]
PIRSFiPIRSF015892. N-myristl_transf. 1 hit.
SUPFAMiSSF55729. SSF55729. 2 hits.
PROSITEiPS00975. NMT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q553B6-1 [UniParc]FASTAAdd to Basket

« Hide

MADDKKKQLE ESKRLVELFK ASSLASKKPK GHEFWDTQPV PKIDDKIIES    50
GPIENKTLDD VRKDPLTLPP AFEWIELDCN KPEELKEIYT LLYENYVEDD 100
DNMFRFDYSP EFLKWALQPP GFLKEWHIGV RVVESKKLVG FISGIPATIR 150
VEGKPITMVE INFLCVHKKL REKRLAPVLI KEVTRRVNLR NIWQAAYTAG 200
VVLPKPVAIC KYWHRSIKQQ KLVEVGFSAI PPKMTMASMV KLYRINDEMK 250
HPLRPLTKED VPSFKVLLDD YLSKYKIAPE FTTDEDVWHW FETRKDVITC 300
YVKVDESTKK VTDAFSFYNL PSTIIGNAKH NTLKAAFSFY NVATTMSITD 350
LVGDALVTAK KMDYDVFNCL DVFENSTFFK DLKFAVGDGD LQYYLYNYST 400
PTKKSSEIGL VLL 413
Length:413
Mass (Da):47,700
Last modified:January 19, 2010 - v2
Checksum:iB25A64368D84FEA9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000013 Genomic DNA. Translation: EAL69682.2.
RefSeqiXP_643504.2. XM_638412.2.

Genome annotation databases

EnsemblProtistsiDDB0302502; DDB0302502; DDB_G0275863.
GeneIDi8620085.
KEGGiddi:DDB_G0275863.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000013 Genomic DNA. Translation: EAL69682.2 .
RefSeqi XP_643504.2. XM_638412.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDBDRAFT_0217694.

Proteomic databases

PRIDEi Q553B6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0302502 ; DDB0302502 ; DDB_G0275863 .
GeneIDi 8620085.
KEGGi ddi:DDB_G0275863.

Organism-specific databases

dictyBasei DDB_G0275863. nmt.

Phylogenomic databases

eggNOGi COG5092.
KOi K00671.
OMAi QRTIKLY.
PhylomeDBi Q553B6.

Family and domain databases

Gene3Di 3.40.630.30. 2 hits.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000903. MyristoylCoA_TrFase.
IPR022677. MyristoylCoA_TrFase_C.
IPR022678. MyristoylCoA_TrFase_CS.
IPR022676. MyristoylCoA_TrFase_N.
[Graphical view ]
PANTHERi PTHR11377. PTHR11377. 1 hit.
Pfami PF01233. NMT. 1 hit.
PF02799. NMT_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF015892. N-myristl_transf. 1 hit.
SUPFAMi SSF55729. SSF55729. 2 hits.
PROSITEi PS00975. NMT_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiNMT_DICDI
AccessioniPrimary (citable) accession number: Q553B6
Secondary accession number(s): Q869M9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: January 19, 2010
Last modified: September 3, 2014
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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