Q55367 (CYNS_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyanate hydratase
Short name=Cyanase
EC=4.2.1.104

Alternative name(s):
Cyanate hydrolase
Cyanate lyase

Gene names

Name:	cynS
Ordered Locus Names:	slr0899

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	149 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. HAMAP MF_00535
Catalytic activity	Cyanate + HCO3- + 2 H+ = NH3 + 2 CO2. HAMAP MF_00535
Sequence similarities	Belongs to the cyanase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cyanate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro cyanate hydratase activity Inferred from electronic annotation. Source: EC hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 149	149	Cyanate hydratase HAMAP MF_00535		PRO_0000187532
Sites
	Active site	90	1	By similarity
	Active site	93	1	By similarity
	Active site	116	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q55367 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8335E4258F19E5E3	FASTA	149	16,532
	10 20 30 40 50 60 MAGTEISAIT TKLLEAKKAK GITFADLEQL LGRDEVWIAA VIYRQASASV DEAEKLLHCL 70 80 90 100 110 120 GLSDDLVPEL TAPSVKGLGP VVPTDPLIYR FYEIMQVYGM PMKEVIHEKF GDGIMSAIDF 130 140 TLDIEKEADP KGDRVKVTMN GKFLPYKKW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[3]	"Identification and nitrogen regulation of the cyanase gene from the cyanobacteria Synechocystis sp. strain PCC 6803 and Synechococcus sp. strain PCC 7942." Harano Y., Suzuki I., Maeda S., Kaneko T., Tabata S., Omata T. J. Bacteriol. 179:5744-5750(1997) [PubMed: 9294430] [Abstract] Cited for: CHARACTERIZATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA10449.1.
PIR	S75714.
RefSeq	NP_442379.1. NC_000911.1.
3D structure databases
ProteinModelPortal	Q55367.
ModBase	Search...
Protein-protein interaction databases
STRING	Q55367.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	952433.
GenomeReviews	Gene locus slr0899 in contig BA000022_GR.
KEGG	syn:slr0899.
NMPDR	fig|1148.1.peg.2480.
PATRIC	23842444. VBISynSp132158_2762.
Phylogenomic databases
eggNOG	COG1513.
HOGENOM	HBG317643.
OMA	FYRQASA.
PhylomeDB	Q55367.
ProtClustDB	PRK02866.
Enzyme and pathway databases
BioCyc	SSP1148:SLR0899-MONOMER.
BRENDA	4.2.1.104. 6185.
Family and domain databases
HAMAP	MF_00535. Cyanate_hydrat. [Tree]
InterPro	IPR008076. Cyanase. IPR003712. Cyanate_lyase_C. IPR010982. Lambda_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.1160.10. Cyanate_lyase_C. 1 hit. G3DSA:1.10.260.40. G3DSA:1.10.260.40. 1 hit.
KO	K01725.
Pfam	PF02560. Cyanate_lyase. 1 hit. [Graphical view]
PIRSF	PIRSF001263. Cyanate_hydratas. 1 hit.
PRINTS	PR01693. CYANASE.
SUPFAM	SSF55234. Cyanate_lyase_C. 1 hit. SSF47413. Lambda_like_DNA. 1 hit.
TIGRFAMs	TIGR00673. CynS. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYNS_SYNY3

Accession

Primary (citable) accession number: Q55367

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program