Reviewed, UniProtKB/Swiss-Prot Q552P3 (ABCAB_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter A family member 11
Alternative name(s):
    ABC transporter ABCA.11

Gene names

Name:	abcA11
ORF Names:	DDB_G0275453

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	834 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. ABCA family. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 834	834	ABC transporter A family member 11		PRO_0000363843
Regions
	Transmembrane	35 – 55	21	Potential
	Transmembrane	188 – 208	21	Potential
	Transmembrane	235 – 255	21	Potential
	Transmembrane	269 – 289	21	Potential
	Transmembrane	297 – 319	23	Potential
	Transmembrane	324 – 346	23	Potential
	Transmembrane	355 – 375	21	Potential
	Domain	452 – 693	242	ABC transporter
	Nucleotide binding	495 – 502	8	ATP Potential
	Compositional bias	69 – 76	8	Poly-Asn
	Compositional bias	423 – 427	5	Poly-Asn
	Compositional bias	757 – 762	6	Poly-Ser
	Compositional bias	790 – 830	41	Poly-Asn

Sequences

	Sequence		Length	Mass (Da)
	Q552P3-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: B93940CF79326194	FASTA	834	94,603
	10 20 30 40 50 60 MRHQNKNHKQ RPSFLSQFLV ILWFRTKLSI RDKKFFILGI LLPMISIGAS IILNNVLVFG 70 80 90 100 110 120 PGSDFQKTNN NLNNNNIFIT PKTLNSQQET LINTMKLQYS LNYTYLDDDT DLPNYIENKS 130 140 150 160 170 180 LSSLDYGISF IGSNGINIYY NSSIESIPSF VHSFFISLFK INGINLQLNE TITVLSSEVT 190 200 210 220 230 240 FDAFYLLMPM ILQYGFVFFI PYFAILIVTD RDKGFKNHLI LNSLRTSVYW FGNLVFDYLI 250 260 270 280 290 300 FLIPTIIGWI LLYSFKIDGI YSDNSGKSFL LFLTFGISAI PFGFVLQFIF DKEETANKWL 310 320 330 340 350 360 YPFTSIVTSI PSALISVAFP TSTPLIVELL LSILPTFSFC NGLKALTYNN SSTVSYTILI 370 380 390 400 410 420 QLLSGLIYLI LIYFIDNYKK PKKNEIINDE DSESIINNQI IEDNDVLNEK EKIKRLVRDG 430 440 450 460 470 480 GGNNNNNKKN NSYPKIVVDG IYKQFIQPKP TLDKPSIIER CSGGTKATKK NSIIKKAVDG 490 500 510 520 530 540 IWFSVEKNEI FGLLGPNGSG KSTCLNLLTG LLKADQGDGY LSGKSIDKDK DVFQSIGSCA 550 560 570 580 590 600 QNDILFENLT IYEHLYLFSR LKSITTTKSE LEDEIDFYIN KFSIQSFKNK KSSDLSGGTK 610 620 630 640 650 660 RKLSVACCLI GDPQVVLLDE PSTSLDPISR NELHSLIDEL KVNKSIIMTT HSINEINQCC 670 680 690 700 710 720 NRVAIMVDGK IRCIGTPNHL KHKYGSGYTI DIIPNNYLNN SYEIHNFMAQ TFPNATRVER 730 740 750 760 770 780 LGRFISYDLP SQNQQSLSTI FRILQSNKQR LQILDFSASS SSLEKVFLKF ANLQEEINKQ 790 800 810 820 830 QTNNKSNIIN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNTNNNTNNN QLIN

References

[1]	"Sequence and analysis of chromosome 2 of Dictyostelium discoideum." Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A. Nature 418:79-85(2002) [PubMed: 12097910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000013 Genomic DNA. Translation: EAL69477.1.
RefSeq	XP_643638.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q552P3.
Genome annotation databases
GeneID	3394794.
GenomeReviews	Gene locus abcA11 in contig CM000151_GR.
KEGG	ddi:DDB_0219981.
Organism-specific databases
dictyBase	DDB_G0275453. abcA11.
Phylogenomic databases
OMA	IINDEDS
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. False negative. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCAB_DICDI

Accession

Primary (citable) accession number: Q552P3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	May 24, 2005
Last modified:	November 24, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)