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Protein

Mitochondrial substrate carrier family protein H

Gene

mcfH

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial substrate carrier family protein H
Alternative name(s):
Solute carrier family 25 member 40 homolog
Gene namesi
Name:mcfH
Synonyms:slc25a40
ORF Names:DDB_G0275985
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0275985. mcfH.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 55Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei96 – 112Helical; Name=2Sequence analysisAdd BLAST17
Transmembranei133 – 151Helical; Name=3Sequence analysisAdd BLAST19
Transmembranei175 – 192Helical; Name=4Sequence analysisAdd BLAST18
Transmembranei262 – 282Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei340 – 357Helical; Name=6Sequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003294121 – 366Mitochondrial substrate carrier family protein HAdd BLAST366

Proteomic databases

PaxDbiQ552L9.

Structurei

3D structure databases

ProteinModelPortaliQ552L9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati29 – 121Solcar 1Add BLAST93
Repeati132 – 243Solcar 2Add BLAST112
Repeati259 – 360Solcar 3Add BLAST102

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi7 – 23Poly-AsnAdd BLAST17

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0761. Eukaryota.
ENOG410XQVP. LUCA.
InParanoidiQ552L9.
KOiK15119.
OMAiKWLCEKS.
PhylomeDBiQ552L9.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom_sf.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q552L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSNSVNNNN NNNNINNSNS NNNDSNIHKN VKKLMVASIF GGIMSSLIVT
60 70 80 90 100
PLDVVKTRLQ TQNTGSHINQ KHVFKGTLDA FKKIYKNEGP LTFWRGVTPS
110 120 130 140 150
LLMTIPSATI YFTSYEYLKE YLYQFNDTEA YNIYTVPLVA GTLARIFSAS
160 170 180 190 200
VTSPFELLRT NSQGIVLQNA YKNTVAMAAS SSTATIGTIP LSSEQRFNSF
210 220 230 240 250
KLYRDIVNNV GIKGLWRGLG PTLVRDVPFS AIYWAGYEVL KNKLMKSQID
260 270 280 290 300
PNFSRNSKSP FFINFIAGAT SGTLAAVLTT PIDVIKTRIQ MSAQQTLSPS
310 320 330 340 350
LTPQQQLDFI KKNNSSIYHL KQILSQEGWK GLTKGLVPRV AKVSPACAIM
360
ISTFEYIKQS HIADDN
Length:366
Mass (Da):40,633
Last modified:May 24, 2005 - v1
Checksum:i2479A3C22ED8EE84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000013 Genomic DNA. Translation: EAL69449.1.
RefSeqiXP_643363.1. XM_638271.1.

Genome annotation databases

EnsemblProtistsiEAL69449; EAL69449; DDB_G0275985.
GeneIDi8620246.
KEGGiddi:DDB_G0275985.

Similar proteinsi

Entry informationi

Entry nameiS2540_DICDI
AccessioniPrimary (citable) accession number: Q552L9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families