Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q55233

- DRGA_SYNY3

UniProt

Q55233 - DRGA_SYNY3

Protein

Protein DrgA

Gene

drgA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Controls resistance to the herbicide Dinoseb and metronidazole. Involved in detoxification of Dinoseb via the reduction of the nitro group(s) and this process is accompanied by the formation of toxic superoxide anions.

    Cofactori

    FMN.Curated

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    GO - Biological processi

    1. response to herbicide Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Herbicide resistance

    Keywords - Ligandi

    Flavoprotein, FMN, NAD, NADP

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein DrgA
    Gene namesi
    Name:drgA
    Ordered Locus Names:slr1719
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 210210Protein DrgAPRO_0000072722Add
    BLAST

    Proteomic databases

    PaxDbiQ55233.

    Interactioni

    Protein-protein interaction databases

    IntActiQ55233. 1 interaction.
    STRINGi1148.slr1719.

    Structurei

    3D structure databases

    ProteinModelPortaliQ55233.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the nitroreductase family.Curated

    Phylogenomic databases

    eggNOGiCOG0778.
    HOGENOMiHOG000146739.
    OrthoDBiEOG6N947Z.
    PhylomeDBiQ55233.

    Family and domain databases

    Gene3Di3.40.109.10. 1 hit.
    InterProiIPR029479. Nitroreductase.
    IPR000415. Nitroreductase-like.
    [Graphical view]
    PfamiPF00881. Nitroreductase. 1 hit.
    [Graphical view]
    SUPFAMiSSF55469. SSF55469. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q55233-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDTFDAIYQR RSVKHFDPDH RLTAEEERKL HEAAIQAPTS FNIQLWRFLI    50
    IRDPQLRQTI REKYGNQAQM TDASLLILVA ADVNAWDKDP ARYWRNAPRE 100
    VANYLVGAIA SFYGGKPQLQ RDEAQRSIGM AMQNLMLAAK AMGYDSCPMI 150
    GFDLQKVAEL VKLPADYAIG PMVAIGKRTE DAPGKRRSNS PGRIPLGKLL 200
    CLTKVWCLAI 210
    Length:210
    Mass (Da):23,703
    Last modified:November 1, 1996 - v1
    Checksum:iC29A1293996EBB95
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti31 – 311H → L in BAA17909. (PubMed:8905231)Curated
    Sequence conflicti45 – 451L → H in BAA17909. (PubMed:8905231)Curated
    Sequence conflicti183 – 21028PGKRR…WCLAI → RAKGGQTPLEELVWENSF(PubMed:8905231)CuratedAdd
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L29426 Genomic DNA. Translation: AAA91952.1.
    BA000022 Genomic DNA. Translation: BAA17909.1.
    PIRiS75047.
    RefSeqiNP_441229.1. NC_000911.1.
    YP_005651286.1. NC_017277.1.
    YP_007451111.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA17909; BAA17909; BAA17909.
    GeneIDi954571.
    KEGGisyn:slr1719.
    syy:SYNGTS_1333.
    syz:MYO_113450.
    PATRICi23839798. VBISynSp132158_1460.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L29426 Genomic DNA. Translation: AAA91952.1 .
    BA000022 Genomic DNA. Translation: BAA17909.1 .
    PIRi S75047.
    RefSeqi NP_441229.1. NC_000911.1.
    YP_005651286.1. NC_017277.1.
    YP_007451111.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali Q55233.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q55233. 1 interaction.
    STRINGi 1148.slr1719.

    Proteomic databases

    PaxDbi Q55233.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA17909 ; BAA17909 ; BAA17909 .
    GeneIDi 954571.
    KEGGi syn:slr1719.
    syy:SYNGTS_1333.
    syz:MYO_113450.
    PATRICi 23839798. VBISynSp132158_1460.

    Phylogenomic databases

    eggNOGi COG0778.
    HOGENOMi HOG000146739.
    OrthoDBi EOG6N947Z.
    PhylomeDBi Q55233.

    Family and domain databases

    Gene3Di 3.40.109.10. 1 hit.
    InterProi IPR029479. Nitroreductase.
    IPR000415. Nitroreductase-like.
    [Graphical view ]
    Pfami PF00881. Nitroreductase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55469. SSF55469. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Resistance to nitrophenolic herbicides and metronidazole in the cyanobacterium Synechocystis sp. PCC 6803 as a result of the inactivation of a nitroreductase-like protein encoded by drgA gene."
      Elanskaya I.V., Chesnavichene E.A., Vernotte C., Astier C.
      FEBS Lett. 428:188-192(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.
    3. "Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes."
      Sazuka T., Ohara O.
      Electrophoresis 18:1252-1258(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-17.

    Entry informationi

    Entry nameiDRGA_SYNY3
    AccessioniPrimary (citable) accession number: Q55233
    Secondary accession number(s): P73850
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3