Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Acetolactate synthase small subunit

Gene

ilvH

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2 pyruvate = 2-acetolactate + CO2.

Pathwayi: L-isoleucine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-isoleucine from 2-oxobutanoate.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Acetolactate synthase small subunit (ilvH), Acetolactate synthase (ilvG)
  2. Ketol-acid reductoisomerase (NADP(+)) (ilvC)
  3. Dihydroxy-acid dehydratase (ilvD)
  4. Probable branched-chain-amino-acid aminotransferase (ilvE)
This subpathway is part of the pathway L-isoleucine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-isoleucine from 2-oxobutanoate, the pathway L-isoleucine biosynthesis and in Amino-acid biosynthesis.

Pathwayi: L-valine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-valine from pyruvate.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Acetolactate synthase small subunit (ilvH), Acetolactate synthase (ilvG)
  2. Ketol-acid reductoisomerase (NADP(+)) (ilvC)
  3. Dihydroxy-acid dehydratase (ilvD)
  4. Probable branched-chain-amino-acid aminotransferase (ilvE)
This subpathway is part of the pathway L-valine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-valine from pyruvate, the pathway L-valine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processAmino-acid biosynthesis, Branched-chain amino acid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00047; UER00055
UPA00049; UER00059

Names & Taxonomyi

Protein namesi
Recommended name:
Acetolactate synthase small subunit (EC:2.2.1.6)
Alternative name(s):
Acetohydroxy-acid synthase small subunit
Short name:
AHAS
Short name:
ALS
Gene namesi
Name:ilvH
Synonyms:ilvN
Ordered Locus Names:sll0065
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001514181 – 172Acetolactate synthase small subunitAdd BLAST172

Proteomic databases

PaxDbiQ55141
PRIDEiQ55141

Interactioni

Subunit structurei

Dimer of large and small chains.By similarity

Protein-protein interaction databases

IntActiQ55141, 2 interactors
STRINGi1148.SYNGTS_2312

Structurei

3D structure databases

ProteinModelPortaliQ55141
SMRiQ55141
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 78ACTPROSITE-ProRule annotationAdd BLAST75

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000046747
InParanoidiQ55141
KOiK01653
OMAiRTGKIAM
PhylomeDBiQ55141

Family and domain databases

Gene3Di3.30.70.1150, 1 hit
InterProiView protein in InterPro
IPR004789 Acetalactate_synth_ssu
IPR027271 Acetolactate_synth/TF_NikR_C
IPR019455 Acetolactate_synth_ssu_C
IPR002912 ACT_dom
PANTHERiPTHR30239 PTHR30239, 1 hit
PfamiView protein in Pfam
PF10369 ALS_ss_C, 1 hit
TIGRFAMsiTIGR00119 acolac_sm, 1 hit
PROSITEiView protein in PROSITE
PS51671 ACT, 1 hit

Sequencei

Sequence statusi: Complete.

Q55141-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHTLSVLVE DEAGVLTRIA GLFARRGFNI ESLAVGSAEQ GDVSRITMVV
60 70 80 90 100
PGDENTIEQL TKQLYKLVNV IKVQDITETP CVERELMLVK VSANAPNRAE
110 120 130 140 150
VIELAQVFRA RIVDISEDTV TIEVVGDPGK MVAILQMLAK FGIKEVARTG
160 170
KIALVRESGV NTEYLKSLES KF
Length:172
Mass (Da):18,871
Last modified:May 30, 2000 - v2
Checksum:iCF266998F9BCA806
GO

Sequence cautioni

The sequence BAA10276 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA10276.1 Different initiation.
PIRiS74358

Genome annotation databases

EnsemblBacteriaiBAA10276; BAA10276; BAA10276
KEGGisyn:sll0065

Similar proteinsi

Entry informationi

Entry nameiILVH_SYNY3
AccessioniPrimary (citable) accession number: Q55141
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: April 25, 2018
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health