Q55141 (ILVH_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetolactate synthase small subunit
EC=2.2.1.6

Alternative name(s):
Acetohydroxy-acid synthase small subunit
Short name=AHAS
Short name=ALS

Gene names

Name:	ilvH
Synonyms:	ilvN
Ordered Locus Names:	sll0065

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	172 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 pyruvate = 2-acetolactate + CO2.
Pathway	Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4. Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.
Subunit structure	Dimer of large and small chains By similarity.
Sequence similarities	Belongs to the acetolactate synthase small subunit family. Contains 1 ACT domain.
Sequence caution	The sequence BAA10276.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Branched-chain amino acid biosynthesis
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	isoleucine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway valine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	acetolactate synthase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 172	172	Acetolactate synthase small subunit		PRO_0000151418
Regions
	Domain	3 – 76	74	ACT

Sequences

	Sequence		Length	Mass (Da)
	Q55141 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: CF266998F9BCA806	FASTA	172	18,871
	10 20 30 40 50 60 MKHTLSVLVE DEAGVLTRIA GLFARRGFNI ESLAVGSAEQ GDVSRITMVV PGDENTIEQL 70 80 90 100 110 120 TKQLYKLVNV IKVQDITETP CVERELMLVK VSANAPNRAE VIELAQVFRA RIVDISEDTV 130 140 150 160 170 TIEVVGDPGK MVAILQMLAK FGIKEVARTG KIALVRESGV NTEYLKSLES KF

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA10276.1. Different initiation.
PIR	S74358.
RefSeq	NP_442206.1. NC_000911.1. YP_007452082.1. NC_020286.1.
3D structure databases
ProteinModelPortal	Q55141.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q55141. 2 interactions.
STRING	1148.sll0065.
Proteomic databases
PaxDb	Q55141.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA10276; BAA10276; BAA10276.
GeneID	14617758. 952587.
KEGG	syn:sll0065.
PATRIC	23842034. VBISynSp132158_2559.
Phylogenomic databases
eggNOG	COG0440.
HOGENOM	HOG000046747.
KO	K01653.
OMA	YNIASLT.
ProtClustDB	PRK11895.
Enzyme and pathway databases
UniPathway	UPA00047; UER00055. UPA00049; UER00059.
Family and domain databases
InterPro	IPR004789. Acetalactate_synth_ssu. IPR019455. Acetolactate_synth_ssu_C. IPR002912. ACT_dom. [Graphical view]
Pfam	PF01842. ACT. 1 hit. PF10369. ALS_ss_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR00119. acolac_sm. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ILVH_SYNY3

Accession

Primary (citable) accession number: Q55141

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 30, 2000
Last modified:	May 1, 2013
This is version 85 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program