Reviewed, UniProtKB/Swiss-Prot Q55128 (AAT_SYNY3)

Names and origin

Protein names

Recommended name:
    Aspartate aminotransferase
      Short name=AspAT
    EC=2.6.1.1
Alternative name(s):
    Transaminase A

Gene names

Name:	aspC
Ordered Locus Names:	sll0402

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
Cofactor	Pyridoxal phosphate By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro L-aspartate:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	Aspartate aminotransferase		PRO_0000123854
Amino acid modifications
	Modified residue	238	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q55128-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 7706C9C353EA317F	FASTA	389	42,352
	10 20 30 40 50 60 MRLTQRVSQV VPSITLEITA KAKAMRTEGI DVLSFTAGEP DFTTPPHIVE AAKLALDEGK 70 80 90 100 110 120 TRYGPAAGEP ALRQAIAKKL REKNNLPYEA ANILVTNGGK HSLFNLMLAM IEQGDEVIIP 130 140 150 160 170 180 APYWLSYPEM VRLAEGTPVI VNTTAATDYK ITPEQLRQAI TSKSKLFVLN SPSNPTGAVY 190 200 210 220 230 240 TPAEIRALAA VILEYEDLYV VSDEIYERIL YDGTEHLSIG AVNDEIFQRT IISNGFAKSY 250 260 270 280 290 300 SMTGWRVGYL AGELPLIQAC STIQGHSTSN VCTFAQYGAI AALENPQTCV ETMVKAFTER 310 320 330 340 350 360 RQVIVEGINQ IAGLSCPNPK GAFYVFVDIA KTGLNSLEFS ARLLESHQVA VIPGAAFGAD 370 380 DCVRFSYATD MDTIKQGLAE LERFVSTLA

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA10261.1.
PIR	S74343.
RefSeq	NP_442191.1.
3D structure databases
HSSP	HSSP built from PDB template 1J32 based on UniProtKB Q8RR70.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q55128. 1 interaction.
STRING	Q55128.
Genome annotation databases
GeneID	952600.
GenomeReviews	Gene locus sll0402 in contig BA000022_GR.
KEGG	syn:sll0402.
NMPDR	fig|1148.1.peg.2292.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q55128.
OMA	IYERILY.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0402-MON.
Family and domain databases
InterPro	IPR001176. ACC_synthase. IPR004839. Aminotransferase_I/II. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
PROSITE	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AAT_SYNY3

Accession

Primary (citable) accession number: Q55128

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	November 3, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)