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Protein

Aspartate aminotransferase

Gene

aspC

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381Aspartate; via amide nitrogenBy similarity
Binding sitei124 – 1241AspartateBy similarity
Binding sitei174 – 1741AspartateBy similarity
Binding sitei364 – 3641AspartateBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase (EC:2.6.1.1)
Short name:
AspAT
Alternative name(s):
Transaminase A
Gene namesi
Name:aspC
Ordered Locus Names:sll0402
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Aspartate aminotransferasePRO_0000123854Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei238 – 2381N6-(pyridoxal phosphate)lysineBy similarity

Proteomic databases

PaxDbiQ55128.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

IntActiQ55128. 1 interaction.
STRINGi1148.SYNGTS_2297.

Structurei

3D structure databases

ProteinModelPortaliQ55128.
SMRiQ55128. Positions 1-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0436.
HOGENOMiHOG000223062.
InParanoidiQ55128.
KOiK00812.
OMAiNSITQMA.
OrthoDBiEOG6RRKNS.
PhylomeDBiQ55128.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q55128-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLTQRVSQV VPSITLEITA KAKAMRTEGI DVLSFTAGEP DFTTPPHIVE
60 70 80 90 100
AAKLALDEGK TRYGPAAGEP ALRQAIAKKL REKNNLPYEA ANILVTNGGK
110 120 130 140 150
HSLFNLMLAM IEQGDEVIIP APYWLSYPEM VRLAEGTPVI VNTTAATDYK
160 170 180 190 200
ITPEQLRQAI TSKSKLFVLN SPSNPTGAVY TPAEIRALAA VILEYEDLYV
210 220 230 240 250
VSDEIYERIL YDGTEHLSIG AVNDEIFQRT IISNGFAKSY SMTGWRVGYL
260 270 280 290 300
AGELPLIQAC STIQGHSTSN VCTFAQYGAI AALENPQTCV ETMVKAFTER
310 320 330 340 350
RQVIVEGINQ IAGLSCPNPK GAFYVFVDIA KTGLNSLEFS ARLLESHQVA
360 370 380
VIPGAAFGAD DCVRFSYATD MDTIKQGLAE LERFVSTLA
Length:389
Mass (Da):42,352
Last modified:November 1, 1996 - v1
Checksum:i7706C9C353EA317F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10261.1.
PIRiS74343.
RefSeqiYP_005652250.1. NC_017277.1.
YP_007452067.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA10261; BAA10261; BAA10261.
KEGGisyn:sll0402.
PATRICi23842004. VBISynSp132158_2544.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10261.1.
PIRiS74343.
RefSeqiYP_005652250.1. NC_017277.1.
YP_007452067.1. NC_020286.1.

3D structure databases

ProteinModelPortaliQ55128.
SMRiQ55128. Positions 1-385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ55128. 1 interaction.
STRINGi1148.SYNGTS_2297.

Proteomic databases

PaxDbiQ55128.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10261; BAA10261; BAA10261.
KEGGisyn:sll0402.
PATRICi23842004. VBISynSp132158_2544.

Phylogenomic databases

eggNOGiCOG0436.
HOGENOMiHOG000223062.
InParanoidiQ55128.
KOiK00812.
OMAiNSITQMA.
OrthoDBiEOG6RRKNS.
PhylomeDBiQ55128.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiAAT_SYNY3
AccessioniPrimary (citable) accession number: Q55128
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: June 24, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.