Q55119 (EFP_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor P
Short name=EF-P

Gene names

Name:	efp
Ordered Locus Names:	slr0434

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase By similarity. HAMAP-Rule MF_00141
Pathway	Protein biosynthesis; polypeptide chain elongation. HAMAP-Rule MF_00141
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the elongation factor P family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Elongation factor P HAMAP-Rule MF_00141		PRO_0000094354

Sequences

	Sequence		Length	Mass (Da)
	Q55119 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: B7D900A822B94938	FASTA	187	20,406
	10 20 30 40 50 60 MISSNDFRTG TSIVMDGAVW KVVEFLHVKP GKGSAFVRTK LKSVQTGNVV EKTFRAGETV 70 80 90 100 110 120 PQANIEKSVM QHTYKDGDQY VFMDMETFEE VSIAPDTLGD KAKFIKEEME VSVVTWDGTI 130 140 150 160 170 180 LDVELPTSVV LEIVETDPGV KGDTATGGTK PAILETGAQV MVPLFIAQGE RIKVDTRDGS YLGRDNA

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

[2]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA10251.1.
PIR	S74333.
RefSeq	NP_442181.1. NC_000911.1. YP_005652240.1. NC_017277.1. YP_007452057.1. NC_020286.1.
3D structure databases
ProteinModelPortal	Q55119.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q55119. 1 interaction.
STRING	1148.slr0434.
Proteomic databases
PaxDb	Q55119.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA10251; BAA10251; BAA10251.
GeneID	12253458. 14617733. 952603.
KEGG	syn:slr0434. syy:SYNGTS_2287.
PATRIC	23841984. VBISynSp132158_2534.
Phylogenomic databases
eggNOG	COG0231.
HOGENOM	HOG000010048.
KO	K02356.
OMA	NDIRPGQ.
ProtClustDB	PRK00529.
Enzyme and pathway databases
UniPathway	UPA00345.
Family and domain databases
Gene3D	2.30.30.30. 1 hit. 2.40.50.140. 2 hits.
HAMAP	MF_00141. EF-P.
InterPro	IPR015365. Elong-fact-P_C. IPR012340. NA-bd_OB-fold. IPR014722. Rib_L2_dom2. IPR020599. Transl_elong_fac_P/YeiP. IPR013185. Transl_elong_KOW-like. IPR001059. Transl_elong_P/YeiP_cen. IPR013852. Transl_elong_P/YeiP_CS. IPR011768. Transl_elongation_fac_P. IPR008991. Translation_prot_SH3-like. [Graphical view]
Pfam	PF01132. EFP. 1 hit. PF08207. EFP_N. 1 hit. PF09285. Elong-fact-P_C. 1 hit. [Graphical view]
PIRSF	PIRSF005901. EF-P. 1 hit.
SMART	SM00841. Elong-fact-P_C. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 2 hits. SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR00038. efp. 1 hit.
PROSITE	PS01275. EFP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFP_SYNY3

Accession

Primary (citable) accession number: Q55119

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program