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Q55034 (STPA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucosylglycerol-phosphate phosphatase

Short name=GGP-P
EC=3.1.3.69
Alternative name(s):
Glucosylglycerol 3-phosphatase
Salt tolerance protein A
Gene names
Name:stpA
Ordered Locus Names:slr0746
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaChroococcalesSynechocystis

Protein attributes

Sequence length422 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Phosphorylates glucosylglycerol-phosphate the precursor of the osmoprotectant glucosylglycerol necessary for salt adaptation of Synechocystis.

Catalytic activity

2-(beta-D-glucosyl)-sn-glycerol-3-phosphate + H2O = 2-(beta-D-glucosyl)-sn-glycerol + phosphate.

Subunit structure

Monomer Probable. Interacts with GGPS Probable. Ref.5

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processsignal transduction

Inferred from electronic annotation. Source: InterPro

   Cellular componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular functionacid phosphatase activity

Inferred from electronic annotation. Source: InterPro

glucosylglycerol 3-phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 422422Glucosylglycerol-phosphate phosphatase
PRO_0000114472

Sites

Active site4031Proton donor By similarity

Experimental info

Sequence conflict3841D → E in CAA53245. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q55034 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: E9C58CBC91A938F2

FASTA42246,542
        10         20         30         40         50         60 
MVLHQQRFSL DHGAFCQTLA QTENLLIVQD LDGVCMELVQ DPLSRRLDAD YVRATTLFAE 

        70         80         90        100        110        120 
HFYVLTNGEH VGKRGVQGIV EQSFGDASFV QQEGLYLPGL AAGGVQWQDR HGKVSHPGVG 

       130        140        150        160        170        180 
QTELEFLAAV PEKITNCLKT FFGDRPHSLS PEQLQTGIEA SVLDNVASPT ANLNTLANLL 

       190        200        210        220        230        240 
QDFPQIYRDL QETMAQLLDQ LMAEAVAQGL GNSFFVHYAP NLGRDERGKE IIRWAKAGDS 

       250        260        270        280        290        300 
GTTDFQFMLR GGVKEAGVLA LLNRYYHNRT GQYPLGESFS ARQAPPSHQD LLHLVKAQFD 

       310        320        330        340        350        360 
PALMPLIIGV GDTVTSQVDE ATGEIRRGGS DRQFLQLIQD LGDWGNHGNL VVYVDSSQGE 

       370        380        390        400        410        420 
VKNRQPLQLE TVAGQTQVVA GPGDMRDREE PLKINVAFPG GHDQYVAAFK QAAQRRRVHF 


SQ 

« Hide

References

« Hide 'large scale' references
[1]"A gene stpA involved in the establishment of salt tolerance in the cyanobacterium Synechocystis PCC6803."
Onana B., Jeanjean R., Joset F.
Russ. J. Plant Physiol. 41:176-183(1994)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Characterization of a glucosylglycerol-phosphate-accumulating, salt-sensitive mutant of the cyanobacterium Synechocystis sp. strain PCC 6803."
Hagemann M., Richter S., Zuther E., Schoor A.
Arch. Microbiol. 166:83-91(1996) [PubMed: 8772170] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[4]"The stpA gene form synechocystis sp. strain PCC 6803 encodes the glucosylglycerol-phosphate phosphatase involved in cyanobacterial osmotic response to salt shock."
Hagemann M., Schoor A., Jeanjean R., Zuther E., Joset F.
J. Bacteriol. 179:1727-1733(1997) [PubMed: 9045835] [Abstract]
Cited for: CHARACTERIZATION.
[5]"A membrane-bound FtsH protease is involved in osmoregulation in Synechocystis sp. PCC 6803: the compatible solute synthesizing enzyme GgpS is one of the targets for proteolysis."
Stirnberg M., Fulda S., Huckauf J., Hagemann M., Kramer R., Marin K.
Mol. Microbiol. 63:86-102(2007) [PubMed: 17116240] [Abstract]
Cited for: POSSIBLE INTERACTION WITH GGPS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U32936 Genomic DNA. Translation: AAB41279.1.
X75566 Genomic DNA. Translation: CAA53245.1.
BA000022 Genomic DNA. Translation: BAA18740.1.
PIRS76828.
RefSeqNP_442928.1. NC_000911.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ55034. 1 interaction.
STRINGQ55034.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID953064.
GenomeReviewsGene locus slr0746 in contig BA000022_GR.
KEGGsyn:slr0746.
NMPDRfig|1148.1.peg.3029.
PATRIC23843662. VBISynSp132158_3361.

Phylogenomic databases

eggNOGNOG45088.
HOGENOMHBG284536.
OMAQDLDGVC.
PhylomeDBQ55034.
ProtClustDBCLSK893778.

Enzyme and pathway databases

BioCycSSP1148:SLR0746-MONOMER.

Family and domain databases

InterProIPR012765. GGPPase.
IPR000560. His_Pase_superF_clade-2.
IPR000198. RhoGAP_dom.
[Graphical view]
Gene3DG3DSA:1.10.555.10. RhoGAP. 1 hit.
KOK05978.
PfamPF09506. Salt_tol_Pase. 1 hit.
[Graphical view]
PIRSFPIRSF020945. GGPPase. 1 hit.
TIGRFAMsTIGR02399. Salt_tol_Pase. 1 hit.
PROSITEPS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSTPA_SYNY3
AccessionPrimary (citable) accession number: Q55034
Secondary accession number(s): Q54787
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: November 1, 1996
Last modified: January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families