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Q55025 (SRPA_SYNE7) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Catalase-related peroxidase

EC=1.11.1.-
Alternative name(s):
Protein SrpA
Sulfur-regulated plasmid-encoded protein A
Gene names
Name:srpA
Ordered Locus Names:Synpcc7942_B2620
ORF Names:pANL46
Encoded onPlasmid pANL
OrganismSynechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) [Complete proteome] [HAMAP]
Taxonomic identifier1140 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Has an organic peroxide-dependent peroxidase activity By similarity.

Cofactor

Heme group By similarity.

Subcellular location

Periplasm Ref.1.

Induction

By sulfur deprivation. Ref.1

Disruption phenotype

No significant differences in the growth kinetics of cells grown in medium containing high or low concentrations of sulfate. Ref.1

Sequence similarities

Belongs to the catalase family.

Sequence caution

The sequence AAA85847.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence ABB58649.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Biological processStress response
   Cellular componentPeriplasm
   DomainSignal
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   Technical termComplete proteome
Direct protein sequencing
Plasmid
Gene Ontology (GO)
   Biological_processresponse to oxidative stress

Inferred from electronic annotation. Source: InterPro

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncatalase activity

Inferred from electronic annotation. Source: InterPro

heme binding

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Ref.1
Chain32 – 339308Catalase-related peroxidase
PRO_0000004695

Sites

Active site581 By similarity
Metal binding3281Iron (heme axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55025 [UniParc].

Last modified July 15, 1998. Version 2.
Checksum: CD53DE1602528BA8

FASTA33937,055
        10         20         30         40         50         60 
MIRIRNRWFR WLAIALASLV ASIGIATVGF AATGVTPDQV LSAIEGTFGV NVGQRRNHIK 

        70         80         90        100        110        120 
GTCAVGNFVA TTEAKTYSRS PLFSGQSIPV VARFSLAGGN PKAPDTAKNP RGLGLQFQLP 

       130        140        150        160        170        180 
NNRFLNMALL NTPVFGVASP EGFYENILAI RPDPTTGKPD PEKVKAFREK YPENKAQAAF 

       190        200        210        220        230        240 
LASNNPPTSY ANTSYFGLHA FKFINQTNQT RLVRWQFVPQ DGEKRLTDAE LQAAPANFLE 

       250        260        270        280        290        300 
QKLIERTQDS PVKWDFWITL GQPGDAEDNP TIAWPSDRQQ VKVGTLTLTA ASPQPGAACE 

       310        320        330 
GINYDPLVLS DGIEPTNDPV LQFRSGVYAL SYSKRTRGL 

« Hide

References

« Hide 'large scale' references
[1]"Genes encoded on a cyanobacterial plasmid are transcriptionally regulated by sulfur availability and CysR."
Nicholson M.L., Laudenbach D.E.
J. Bacteriol. 177:2143-2150(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 32-52, SUBCELLULAR LOCATION, INDUCTION, DISRUPTION PHENOTYPE, SIGNAL.
Strain: PCC 7942.
[2]"The complete sequence and functional analysis of pANL, the large plasmid of the unicellular freshwater cyanobacterium Synechococcus elongatus PCC 7942."
Chen Y., Holtman C.K., Magnuson R.D., Youderian P.A., Golden S.S.
Plasmid 59:176-192(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: PCC 7942.
[3]"Complete sequence of plasmid 1 of Synechococcus elongatus PCC 7942."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7942.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U20224 Genomic DNA. Translation: AAA85847.1. Different initiation.
AF441790 Genomic DNA. Translation: AAM81171.2.
CP000101 Genomic DNA. Translation: ABB58649.1. Different initiation.
RefSeqNP_665784.2. NC_004073.2.
YP_398718.1. NC_007595.1.

3D structure databases

ProteinModelPortalQ55025.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1140.Synpcc7942_B2620.

Protein family/group databases

PeroxiBase6125. SeKat1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB58649; ABB58649; Synpcc7942_B2620.
GeneID1010222.
3772768.
KEGGsyf:Synpcc7942_B2620.
PATRIC23784928. VBISynElo51371_0015.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0753.
HOGENOMHOG000110273.
KOK03781.
OrthoDBEOG6742T3.
ProtClustDBCLSK638212.

Enzyme and pathway databases

BioCycSYNEL:SYNPCC7942_B2620-MONOMER.

Family and domain databases

Gene3D2.40.180.10. 1 hit.
InterProIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR011614. Catalase_core.
IPR024168. Catalase_SrpA-type_pred.
[Graphical view]
PANTHERPTHR11465. PTHR11465. 1 hit.
PfamPF00199. Catalase. 1 hit.
[Graphical view]
PIRSFPIRSF000296. SrpA. 1 hit.
PRINTSPR00067. CATALASE.
SMARTSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMSSF56634. SSF56634. 1 hit.
PROSITEPS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSRPA_SYNE7
AccessionPrimary (citable) accession number: Q55025
Secondary accession number(s): Q8KUU0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: April 16, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families