Q54Z13 (VATG_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type proton ATPase subunit G
Short name=V-ATPase subunit G

Alternative name(s):
Vacuolar proton pump subunit G

Gene names

Name:	atp6v1g
Synonyms:	vatg
ORF Names:	DDB_G0277971

Organism

Dictyostelium discoideum (Slime mold) [Reference proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit structure	V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d) By similarity.
Sequence similarities	Belongs to the V-ATPase G subunit family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proton transport Inferred from electronic annotation. Source: UniProtKB-KW vacuolar acidification Inferred from sequence or structural similarity. Source: dictyBase
Cellular_component	phagocytic vesicle Inferred from direct assay Ref.2. Source: dictyBase vacuolar proton-transporting V-type ATPase, V1 domain Inferred from sequence or structural similarity. Source: dictyBase
Molecular_function	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 107	107	V-type proton ATPase subunit G		PRO_0000328303

Sequences

	Sequence		Length	Mass (Da)
	Q54Z13 [UniParc]. Last modified May 2, 2006. Version 2. Checksum: 67BC44D8A9A11499	FASTA	107	12,199
	10 20 30 40 50 60 MSSEDGIKKL LDAERTAQKI VADARQDRVQ KLKKAVEEAE KEIKEFREKK DKEYKEYESK 70 80 90 100 YLGASSETAS QLATNANKEI DTIRNETAAN KQKVVDLLIK YAITCDN

References

[1]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	"Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake." Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M., Soldati T. Mol. Cell. Proteomics 5:2228-2243(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Strain: AX2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000023 Genomic DNA. Translation: EAL68158.2.
RefSeq	XP_642039.2. XM_636947.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	44689.DDBDRAFT_0204332.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0238144; DDB0238144; DDB_G0277971.
GeneID	8621251.
KEGG	ddi:DDB_G0277971.
Organism-specific databases
dictyBase	DDB_G0277971. vatG.
Phylogenomic databases
eggNOG	NOG140089.
KO	K02152.
OMA	KHMGSKE.
Family and domain databases
InterPro	IPR005124. V-ATPase_G. [Graphical view]
PANTHER	PTHR12713. PTHR12713. 1 hit.
Pfam	PF03179. V-ATPase_G. 1 hit. [Graphical view]
TIGRFAMs	TIGR01147. V_ATP_synt_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

VATG_DICDI

Accession

Primary (citable) accession number: Q54Z13

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	May 2, 2006
Last modified:	May 1, 2013
This is version 54 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)