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Protein

Integrator complex subunit 5-like protein

Gene

DDB_G0279251

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Integrator complex subunit 5-like protein
Gene namesi
ORF Names:DDB_G0279251
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0279251.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei350 – 370HelicalSequence analysisAdd BLAST21
Transmembranei877 – 897HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003443771 – 1563Integrator complex subunit 5-like proteinAdd BLAST1563

Proteomic databases

PaxDbiQ54X25.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0234101.

Structurei

3D structure databases

SMRiQ54X25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi51 – 58Poly-Asp8
Compositional biasi107 – 132Thr-richAdd BLAST26
Compositional biasi145 – 148Poly-Asn4
Compositional biasi156 – 202Poly-AsnAdd BLAST47
Compositional biasi277 – 288Poly-AsnAdd BLAST12
Compositional biasi295 – 301Poly-Asn7
Compositional biasi376 – 404Gln-richAdd BLAST29
Compositional biasi466 – 496Ser-richAdd BLAST31
Compositional biasi539 – 545Poly-Asn7
Compositional biasi639 – 686Poly-AsnAdd BLAST48
Compositional biasi786 – 818Poly-AsnAdd BLAST33
Compositional biasi853 – 868Poly-AsnAdd BLAST16
Compositional biasi965 – 970Poly-Ser6
Compositional biasi1019 – 1024Poly-Asn6
Compositional biasi1035 – 1039Poly-Asn5
Compositional biasi1161 – 1165Poly-Asp5
Compositional biasi1255 – 1261Poly-Asn7
Compositional biasi1331 – 1336Poly-Gly6
Compositional biasi1499 – 1515Ser-richAdd BLAST17

Sequence similaritiesi

Belongs to the Integrator subunit 5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JQ3C. Eukaryota.
ENOG410ZPWB. LUCA.
InParanoidiQ54X25.
OMAiYILTSIW.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR029444. INTS5_C.
IPR015943. WD40/YVTN_repeat-like_dom.
PfamiView protein in Pfam
PF14838. INTS5_C. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54X25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEEETIEIS EKEKDKERND NQDTLTISWI EDWRNEETAT KNENNKNNNS
60 70 80 90 100
DGDSDDDDYY DDDEEIKNSR YNLFLEKILT LESNSNLKNI LSLNINFKKD
110 120 130 140 150
NKKSKETDTA ATTTTTTTTT TTTTTTTTPT ATANKKYIRT NNLLNNNNSS
160 170 180 190 200
SSSSSNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
210 220 230 240 250
NNGENITYIT SPLSNESLES TEECCFFLVH LPITKDLIFN QFTCLLIHLF
260 270 280 290 300
QIEYNNTIII NNATSSSSVN SLNRSYNNSN NNNNNNYNSY NNRGNNYNNN
310 320 330 340 350
NQQQQQQQNP NLKIRDLEGY QDCSHLKKLC LTIHDYLTQL LQRNPLIWYD
360 370 380 390 400
SIINWSLSTL TIITRLLIIL KNNKSQQQQQ QQQQQQQQQQ QQQQQQQQTK
410 420 430 440 450
NKTQFPPPPP PPLRQPITPI SAMVRERLDF YSFRSLLSLV LHLTRIFSIE
460 470 480 490 500
TFIEKSNVTQ FLDITSKSSS SSSSSSSSSS SSSSSSSSSS SSSSSSKTIK
510 520 530 540 550
PKKLPIYELG WILCHLGKKN PSLILGLTFN HYLKNIGLNS NNNNNKVNSK
560 570 580 590 600
SQYIQDINCF QILEFLALQP SSYLSIIFQQ HIDKIISNHK SNKNKNNTQF
610 620 630 640 650
LKDIKTFLML ITKDDVFLSI GLPIILDKLS PFGINQFDNN NNNNNNNNNN
660 670 680 690 700
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN KNNNNNSIKE DNSSEKDIES
710 720 730 740 750
IKEILEKVLL GNSQVISFYS KRILLVLYHC CFGDSNDITF SSYSTSTLLQ
760 770 780 790 800
IKNQTRYNVS IKLLTSIVKD RLEKQLINKL YSPILNNNNN NNNNNNNNNN
810 820 830 840 850
NNNNNNNNNN NNNNNNNNQQ QQQQSQEIEN STFINNLNQD ENITFYLNQI
860 870 880 890 900
QCNNNNNNNN NNNNNNNNKL IKEKNNIIIK LISLIGMDSI YSSLIILNHI
910 920 930 940 950
ISKLKSNQFI QYFYTLVEQF QAVNSNTIEF FINDLFKSID SFSHDDLITL
960 970 980 990 1000
LNNLLELVKI TPPPSSSSPS NLSIYNETLK CISSNWVVLL KLIKHPNLIE
1010 1020 1030 1040 1050
SNKMMSIEIL YHSFNNRYNN NNNNSQSIQQ LEISNNNNNI KKKEIYPSTL
1060 1070 1080 1090 1100
LSDKEMLEIR VLLEKILNLI FKSFKEKNSF ERLKKFEIYK NLYLLICNGS
1110 1120 1130 1140 1150
SVYFSSTIDL ILDSLFSKKT DMIIKLPILC ALSPANTLPP PNYPANLVNA
1160 1170 1180 1190 1200
GSGSGNFGNG DDDDDEYGDD EYGANRNEKE ELYFKQIINP SLPLSQPLIM
1210 1220 1230 1240 1250
LPMQSSLLEI NYERKYYHYK FNDMNNPNHI PFTNKPKNLK KRIENNQSSA
1260 1270 1280 1290 1300
IDTTNNNNKN NEILTYKKQR MKKKKQSIQQ NGNINNEQQQ EEDDNDDADD
1310 1320 1330 1340 1350
QNEQDDYEKY NILNNENDLQ SFIKSLVLYD GGGGSGFNNH GDINDRLQIL
1360 1370 1380 1390 1400
TNQFLLRVSS PYLEPSYENY QEILPKQSHY ERDIFIRNLF QQNPFLYRVL
1410 1420 1430 1440 1450
EIISIDGREL TKCLEVIKSL LVNEISYWYQ CRNSYSESPI KSSHYHTTIL
1460 1470 1480 1490 1500
LVKALINAEF IIHPLNLSLE LFDKIKAEEI SYILTSIWNF IKDYQPNPSQ
1510 1520 1530 1540 1550
YQSSSSSSSS SSPPSNNTII PTFKRVFSNC NTTPYSLTLK AIFHNHIKEL
1560
CFHYARFFPK KYY
Length:1,563
Mass (Da):180,165
Last modified:May 24, 2005 - v1
Checksum:iACCC952AE734E41B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000030 Genomic DNA. Translation: EAL67774.1.
RefSeqiXP_641752.1. XM_636660.1.

Genome annotation databases

EnsemblProtistsiEAL67774; EAL67774; DDB_G0279251.
GeneIDi8621950.
KEGGiddi:DDB_G0279251.

Entry informationi

Entry nameiINT5_DICDI
AccessioniPrimary (citable) accession number: Q54X25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families