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Q54WS9

- Y9461_DICDI

UniProt

Q54WS9 - Y9461_DICDI

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Protein
Probable protein phosphatase DDB_G0279461
Gene
DDB_G0279461
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi784 – 7841Manganese 1 By similarity
Metal bindingi784 – 7841Manganese 2 By similarity
Metal bindingi785 – 7851Manganese 1; via carbonyl oxygen By similarity
Metal bindingi956 – 9561Manganese 2 By similarity
Metal bindingi996 – 9961Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase DDB_G0279461 (EC:3.1.3.16)
Gene namesi
ORF Names:DDB_G0279461
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0279461.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10061006Probable protein phosphatase DDB_G0279461
PRO_0000369245Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0205778.

Structurei

3D structure databases

ProteinModelPortaliQ54WS9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini639 – 1006368PP2C-like
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili65 – 12258 Reviewed prediction
Add
BLAST
Coiled coili450 – 51667 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi223 – 23412Poly-Asn
Add
BLAST
Compositional biasi244 – 25613Poly-Asn
Add
BLAST
Compositional biasi291 – 2966Poly-Gln
Compositional biasi316 – 35237Poly-Asn
Add
BLAST
Compositional biasi372 – 38110Poly-Asn
Compositional biasi554 – 5607Poly-Asn
Compositional biasi613 – 6219Poly-Asn
Compositional biasi622 – 63918Poly-Thr
Add
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the PP2C family.
Contains 1 PP2C-like domain.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ54WS9.
OMAiMIELAIC.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54WS9-1 [UniParc]FASTAAdd to Basket

« Hide

MMVPSLSTSI SSPALFKNRE GGEEGNDGGL EQLQNQVNDL GDLNFNEEGD     50
YNNDQQPTNE EEGTADNELE SLMSLVNDNN NNNNNTSGID DDNNNDIDDN 100
NNNNNNNNNN NNNNNNNKEG LNDLFISSIN VSTLLNDLDQ LSDTHSHASV 150
SNQSSNGSVR RGYDIKTQRS VGTKGQGGSS GSSPRSNSLR VYRTFPYRGD 200
HHFSWLNNIR DVDSSEDPNS CHNSNNNNKN NKNNQPSSTH DQTNINNNNN 250
NNCNDNEKPI KPNSTNGIRH SRKYKGLQQL DFLGSNIILP QQQQPQPIED 300
NQQVVPQPFQ VDAESNYNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNDNE 350
NNQHPINPVN TQNTQQNVTH SNNNNNNNNN NTAPPNQWSE LIESLGYGSQ 400
SDEQKTFGST LDDLNNANSC SDLKDLIVDG ISINNETSPS QSQEITDFSK 450
IDNLNKNINI NNNNNTDSQQ PLPSIDVNFS HNNNNNNNDN DNNNNNNNNN 500
NNNNNNNNNN NIQDIQIPYH QNDQDYNIQE GNDINNDNYE IRVSNNDDDN 550
DSSNNNNNNN SKFQENLNLL NTGMGGRICK TDQKKQLSRT ITFADPSSIL 600
SFFGSIPTDE DQNNNNNKNK NTTTTTTTTN TTTTTTTTTS ASAAAQNKLD 650
LLSSLSAGQS SGGVGGGNNV LNSSSTPAIK VNHQHKVTEQ NRTSSKISLS 700
TIFPKLPPFT NQQSPPTLSP SKYYYPLLQP EPTTLIRGFS SAADINKRGL 750
KRAKKPMEME DVYLTQYPLG DDQDSQIALF AIFDGHSGKG CAVAAKEIFP 800
NILLKYIKST KNENGGKPIY DMRGVFLNAF KEVDAQLSKF EYEGATATVC 850
LVWRAGHQRF VQSANVGDST AFLSYGNETL FLSKDHRATD PEEIQRIKND 900
GITLTEGQTR INGLMVSRAL GDHFIKHLNC GLSGEPYVSP PISITPFHSH 950
LIVASDGLWD VISGNRAMEI VKVQQTEEKM SNSLLQCAIG SIKAKDNISI 1000
IVVTLQ 1006
Length:1,006
Mass (Da):111,161
Last modified:April 14, 2009 - v2
Checksum:i173B5733030E9B62
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000031 Genomic DNA. Translation: EAL67669.2.
RefSeqiXP_641638.2. XM_636546.2.

Genome annotation databases

EnsemblProtistsiDDB0304651; DDB0304651; DDB_G0279461.
GeneIDi8622044.
KEGGiddi:DDB_G0279461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000031 Genomic DNA. Translation: EAL67669.2 .
RefSeqi XP_641638.2. XM_636546.2.

3D structure databases

ProteinModelPortali Q54WS9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDBDRAFT_0205778.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0304651 ; DDB0304651 ; DDB_G0279461 .
GeneIDi 8622044.
KEGGi ddi:DDB_G0279461.

Organism-specific databases

dictyBasei DDB_G0279461.

Phylogenomic databases

eggNOGi COG0631.
InParanoidi Q54WS9.
OMAi MIELAIC.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiY9461_DICDI
AccessioniPrimary (citable) accession number: Q54WS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: May 14, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3