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Q54WS9

- Y9461_DICDI

UniProt

Q54WS9 - Y9461_DICDI

Protein

Probable protein phosphatase DDB_G0279461

Gene

DDB_G0279461

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 2 (14 Apr 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi784 – 7841Manganese 1By similarity
    Metal bindingi784 – 7841Manganese 2By similarity
    Metal bindingi785 – 7851Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi956 – 9561Manganese 2By similarity
    Metal bindingi996 – 9961Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase DDB_G0279461 (EC:3.1.3.16)
    Gene namesi
    ORF Names:DDB_G0279461
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0279461.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10061006Probable protein phosphatase DDB_G0279461PRO_0000369245Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDBDRAFT_0205778.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54WS9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini639 – 1006368PP2C-likeAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili65 – 12258Sequence AnalysisAdd
    BLAST
    Coiled coili450 – 51667Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi223 – 23412Poly-AsnAdd
    BLAST
    Compositional biasi244 – 25613Poly-AsnAdd
    BLAST
    Compositional biasi291 – 2966Poly-Gln
    Compositional biasi316 – 35237Poly-AsnAdd
    BLAST
    Compositional biasi372 – 38110Poly-Asn
    Compositional biasi554 – 5607Poly-Asn
    Compositional biasi613 – 6219Poly-Asn
    Compositional biasi622 – 63918Poly-ThrAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiCOG0631.
    InParanoidiQ54WS9.
    OMAiMIELAIC.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q54WS9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMVPSLSTSI SSPALFKNRE GGEEGNDGGL EQLQNQVNDL GDLNFNEEGD     50
    YNNDQQPTNE EEGTADNELE SLMSLVNDNN NNNNNTSGID DDNNNDIDDN 100
    NNNNNNNNNN NNNNNNNKEG LNDLFISSIN VSTLLNDLDQ LSDTHSHASV 150
    SNQSSNGSVR RGYDIKTQRS VGTKGQGGSS GSSPRSNSLR VYRTFPYRGD 200
    HHFSWLNNIR DVDSSEDPNS CHNSNNNNKN NKNNQPSSTH DQTNINNNNN 250
    NNCNDNEKPI KPNSTNGIRH SRKYKGLQQL DFLGSNIILP QQQQPQPIED 300
    NQQVVPQPFQ VDAESNYNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNDNE 350
    NNQHPINPVN TQNTQQNVTH SNNNNNNNNN NTAPPNQWSE LIESLGYGSQ 400
    SDEQKTFGST LDDLNNANSC SDLKDLIVDG ISINNETSPS QSQEITDFSK 450
    IDNLNKNINI NNNNNTDSQQ PLPSIDVNFS HNNNNNNNDN DNNNNNNNNN 500
    NNNNNNNNNN NIQDIQIPYH QNDQDYNIQE GNDINNDNYE IRVSNNDDDN 550
    DSSNNNNNNN SKFQENLNLL NTGMGGRICK TDQKKQLSRT ITFADPSSIL 600
    SFFGSIPTDE DQNNNNNKNK NTTTTTTTTN TTTTTTTTTS ASAAAQNKLD 650
    LLSSLSAGQS SGGVGGGNNV LNSSSTPAIK VNHQHKVTEQ NRTSSKISLS 700
    TIFPKLPPFT NQQSPPTLSP SKYYYPLLQP EPTTLIRGFS SAADINKRGL 750
    KRAKKPMEME DVYLTQYPLG DDQDSQIALF AIFDGHSGKG CAVAAKEIFP 800
    NILLKYIKST KNENGGKPIY DMRGVFLNAF KEVDAQLSKF EYEGATATVC 850
    LVWRAGHQRF VQSANVGDST AFLSYGNETL FLSKDHRATD PEEIQRIKND 900
    GITLTEGQTR INGLMVSRAL GDHFIKHLNC GLSGEPYVSP PISITPFHSH 950
    LIVASDGLWD VISGNRAMEI VKVQQTEEKM SNSLLQCAIG SIKAKDNISI 1000
    IVVTLQ 1006
    Length:1,006
    Mass (Da):111,161
    Last modified:April 14, 2009 - v2
    Checksum:i173B5733030E9B62
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000031 Genomic DNA. Translation: EAL67669.2.
    RefSeqiXP_641638.2. XM_636546.2.

    Genome annotation databases

    EnsemblProtistsiDDB0304651; DDB0304651; DDB_G0279461.
    GeneIDi8622044.
    KEGGiddi:DDB_G0279461.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000031 Genomic DNA. Translation: EAL67669.2 .
    RefSeqi XP_641638.2. XM_636546.2.

    3D structure databases

    ProteinModelPortali Q54WS9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDBDRAFT_0205778.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0304651 ; DDB0304651 ; DDB_G0279461 .
    GeneIDi 8622044.
    KEGGi ddi:DDB_G0279461.

    Organism-specific databases

    dictyBasei DDB_G0279461.

    Phylogenomic databases

    eggNOGi COG0631.
    InParanoidi Q54WS9.
    OMAi MIELAIC.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiY9461_DICDI
    AccessioniPrimary (citable) accession number: Q54WS9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 14, 2009
    Last modified: October 1, 2014
    This is version 50 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3