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Protein

Probable protein phosphatase DDB_G0279461

Gene

DDB_G0279461

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi784Manganese 1By similarity1
Metal bindingi784Manganese 2By similarity1
Metal bindingi785Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi956Manganese 2By similarity1
Metal bindingi996Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase DDB_G0279461 (EC:3.1.3.16)
Gene namesi
ORF Names:DDB_G0279461
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0279461

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003692451 – 1006Probable protein phosphatase DDB_G0279461Add BLAST1006

Proteomic databases

PaxDbiQ54WS9
PRIDEiQ54WS9

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0304651

Structurei

3D structure databases

ProteinModelPortaliQ54WS9
SMRiQ54WS9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini744 – 1005PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST262

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili65 – 122Sequence analysisAdd BLAST58
Coiled coili450 – 516Sequence analysisAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi223 – 234Poly-AsnAdd BLAST12
Compositional biasi244 – 256Poly-AsnAdd BLAST13
Compositional biasi291 – 296Poly-Gln6
Compositional biasi316 – 352Poly-AsnAdd BLAST37
Compositional biasi372 – 381Poly-Asn10
Compositional biasi554 – 560Poly-Asn7
Compositional biasi613 – 621Poly-Asn9
Compositional biasi622 – 639Poly-ThrAdd BLAST18

Sequence similaritiesi

In the C-terminal section; belongs to the PP2C family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
InParanoidiQ54WS9
OMAiYRTFPYR

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 4 hits
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q54WS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMVPSLSTSI SSPALFKNRE GGEEGNDGGL EQLQNQVNDL GDLNFNEEGD
60 70 80 90 100
YNNDQQPTNE EEGTADNELE SLMSLVNDNN NNNNNTSGID DDNNNDIDDN
110 120 130 140 150
NNNNNNNNNN NNNNNNNKEG LNDLFISSIN VSTLLNDLDQ LSDTHSHASV
160 170 180 190 200
SNQSSNGSVR RGYDIKTQRS VGTKGQGGSS GSSPRSNSLR VYRTFPYRGD
210 220 230 240 250
HHFSWLNNIR DVDSSEDPNS CHNSNNNNKN NKNNQPSSTH DQTNINNNNN
260 270 280 290 300
NNCNDNEKPI KPNSTNGIRH SRKYKGLQQL DFLGSNIILP QQQQPQPIED
310 320 330 340 350
NQQVVPQPFQ VDAESNYNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNDNE
360 370 380 390 400
NNQHPINPVN TQNTQQNVTH SNNNNNNNNN NTAPPNQWSE LIESLGYGSQ
410 420 430 440 450
SDEQKTFGST LDDLNNANSC SDLKDLIVDG ISINNETSPS QSQEITDFSK
460 470 480 490 500
IDNLNKNINI NNNNNTDSQQ PLPSIDVNFS HNNNNNNNDN DNNNNNNNNN
510 520 530 540 550
NNNNNNNNNN NIQDIQIPYH QNDQDYNIQE GNDINNDNYE IRVSNNDDDN
560 570 580 590 600
DSSNNNNNNN SKFQENLNLL NTGMGGRICK TDQKKQLSRT ITFADPSSIL
610 620 630 640 650
SFFGSIPTDE DQNNNNNKNK NTTTTTTTTN TTTTTTTTTS ASAAAQNKLD
660 670 680 690 700
LLSSLSAGQS SGGVGGGNNV LNSSSTPAIK VNHQHKVTEQ NRTSSKISLS
710 720 730 740 750
TIFPKLPPFT NQQSPPTLSP SKYYYPLLQP EPTTLIRGFS SAADINKRGL
760 770 780 790 800
KRAKKPMEME DVYLTQYPLG DDQDSQIALF AIFDGHSGKG CAVAAKEIFP
810 820 830 840 850
NILLKYIKST KNENGGKPIY DMRGVFLNAF KEVDAQLSKF EYEGATATVC
860 870 880 890 900
LVWRAGHQRF VQSANVGDST AFLSYGNETL FLSKDHRATD PEEIQRIKND
910 920 930 940 950
GITLTEGQTR INGLMVSRAL GDHFIKHLNC GLSGEPYVSP PISITPFHSH
960 970 980 990 1000
LIVASDGLWD VISGNRAMEI VKVQQTEEKM SNSLLQCAIG SIKAKDNISI

IVVTLQ
Length:1,006
Mass (Da):111,161
Last modified:April 14, 2009 - v2
Checksum:i173B5733030E9B62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000031 Genomic DNA Translation: EAL67669.2
RefSeqiXP_641638.2, XM_636546.2

Genome annotation databases

EnsemblProtistsiEAL67669; EAL67669; DDB_G0279461
GeneIDi8622044
KEGGiddi:DDB_G0279461

Entry informationi

Entry nameiY9461_DICDI
AccessioniPrimary (citable) accession number: Q54WS9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: May 23, 2018
This is version 68 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

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