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Q54WR9

- GLNA3_DICDI

UniProt

Q54WR9 - GLNA3_DICDI

Protein

Type-3 glutamine synthetase

Gene

glnA3

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. nitrogen compound metabolic process Source: InterPro
    2. response to bacterium Source: dictyBase

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-3 glutamine synthetase (EC:6.3.1.2)
    Alternative name(s):
    Type-3 glutamate--ammonia ligase
    Short name:
    Type-3 GS
    Gene namesi
    Name:glnA3
    Synonyms:glnB
    ORF Names:DDB_G0279591
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0279591. glnA3.

    Subcellular locationi

    GO - Cellular componenti

    1. phagocytic vesicle Source: dictyBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 735735Type-3 glutamine synthetasePRO_0000330468Add
    BLAST

    Proteomic databases

    PRIDEiQ54WR9.

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Protein-protein interaction databases

    STRINGi44689.DDB_0231551.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54WR9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG3968.
    KOiK01915.
    OMAiGQQLDDH.
    PhylomeDBiQ54WR9.

    Family and domain databases

    Gene3Di3.30.590.10. 2 hits.
    InterProiIPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR022147. GSIII_N.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF12437. GSIII_N. 1 hit.
    [Graphical view]
    PROSITEiPS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54WR9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNRRREFIE YIDSREPVEA DIDISDKADR LTDIYDSDTY GLNAMRETLP    50
    SHCYKKIREV MQTGSALDPE IADMVANGMK EWAIKQGATH YCHWFLPLNG 100
    LAAEKHDSFI SIFPGDDKVL LEFSGMQLIK GEPDASSFPS GGIRSTWEAR 150
    GYTVWDATSP AFIRREKNGA ILCIPTAFCS WTGEALDQKT PLLRSMEYVS 200
    NESIITLSSL FNEKHKRISP TLGIEQEFFL IDRKFYLARP DLVNCGRTLI 250
    GAKPPKGQEM EDHYFGTMNS RIISCIQEVE WKMWRLGMPL KTRHNEVAPG 300
    QYEVAPIFER ANIAADHNMM LMDILKNVST KHGLVCLFHE KPFAGVNGSG 350
    KHNNWSLSTD GGSNLLEPGH TPSQNARFIL FLTAIIRAVD IHADLLRASV 400
    AVPGNEHRLG ANEAPPAIIS IYLGKELDTV INNIINNTDI QAPGSDDMDL 450
    GVVGFPPLPK DSTDRNRTSP FAFTGNKFEF RAVGSSQVVN FPCIVLNTIV 500
    AESLRFIREE ILREMKVSSR QTAFNKIIKD TLIQHVRVVF NGDGYSGDWK 550
    ELAKSRGLAN LPSTPEALTN INSEKNIKLF SESNILSPVE LESRQEILFE 600
    IYNKSIKIEA NSLYDLVSTL VLPACFAHQK NIAESVNSIM PFIQSQKSFS 650
    QPNHQYSHLS EVVESVNLLI EANQKLLALI KQTKDFNSEH SLATFLNQSV 700
    IPQMNEVRKF SDHLEGIVED KSWPVPKYSE ILFLR 735
    Length:735
    Mass (Da):82,616
    Last modified:May 24, 2005 - v1
    Checksum:i9B2B44F894566A08
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000031 Genomic DNA. Translation: EAL67734.1.
    RefSeqiXP_641648.1. XM_636556.1.

    Genome annotation databases

    EnsemblProtistsiDDB0231551; DDB0231551; DDB_G0279591.
    GeneIDi8622055.
    KEGGiddi:DDB_G0279591.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000031 Genomic DNA. Translation: EAL67734.1 .
    RefSeqi XP_641648.1. XM_636556.1.

    3D structure databases

    ProteinModelPortali Q54WR9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0231551.

    Proteomic databases

    PRIDEi Q54WR9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0231551 ; DDB0231551 ; DDB_G0279591 .
    GeneIDi 8622055.
    KEGGi ddi:DDB_G0279591.

    Organism-specific databases

    dictyBasei DDB_G0279591. glnA3.

    Phylogenomic databases

    eggNOGi COG3968.
    KOi K01915.
    OMAi GQQLDDH.
    PhylomeDBi Q54WR9.

    Family and domain databases

    Gene3Di 3.30.590.10. 2 hits.
    InterProi IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR022147. GSIII_N.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF12437. GSIII_N. 1 hit.
    [Graphical view ]
    PROSITEi PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    2. "Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake."
      Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M., Soldati T.
      Mol. Cell. Proteomics 5:2228-2243(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: AX2.

    Entry informationi

    Entry nameiGLNA3_DICDI
    AccessioniPrimary (citable) accession number: Q54WR9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3