Reviewed, UniProtKB/Swiss-Prot Q54W20 (ABCD3_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter D family member 3
Alternative name(s):
    ABC transporter ABCD.3

Gene names

Name:	abcD3
ORF Names:	DDB_G0279919

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	750 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily. [View classification] Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Coiled coil Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 750	750	ABC transporter D family member 3		PRO_0000370851
Regions
	Transmembrane	63 – 83	21	Potential
	Transmembrane	123 – 143	21	Potential
	Transmembrane	188 – 208	21	Potential
	Transmembrane	215 – 235	21	Potential
	Transmembrane	382 – 402	21	Potential
	Domain	74 – 362	289	ABC transmembrane type-1
	Domain	507 – 737	231	ABC transporter
	Nucleotide binding	540 – 547	8	ATP Potential
	Coiled coil	334 – 370	37	Potential
	Compositional bias	15 – 27	13	Poly-Ser
	Compositional bias	299 – 305	7	Poly-His

Sequences

	Sequence		Length	Mass (Da)
	Q54W20-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: EABB7C5ADD2A24E5	FASTA	750	86,589
	10 20 30 40 50 60 MKKNNVNNIT ETLNSSSSSS SSSGSSSDEE VKSKLNFNQT DEMLKKIKEN KFDWALFKRF 70 80 90 100 110 120 IKIVIILYEK PVIPLLLFLL LFGSGVSQTY ISKFTGILLS NIYGSLTSGD KFLFVSSLIK 130 140 150 160 170 180 GCFAIGGSAL FDAIIKFIVS IMAWNWRKTL CLYIQNVYFK KSLFYKILAF DDRIDNPDQR 190 200 210 220 230 240 ITSDIDNFTT LLSSIVSQCI TGPMVVVYYT YLCYTTIDWY APLIVYGYFF LGYFINKLVM 250 260 270 280 290 300 SPMVSINYLQ DKLEGDFRYL HQRIRNFSES IALYNLSKEK QQKKSTTSVD NLDYYDDDHH 310 320 330 340 350 360 YHHHHDDGEE SDEYTDKTKI INRKNKNSKN KRSALLKRSN KNIKNEELLV EEEQAKQQFE 370 380 390 400 410 420 ALLKNKKRVI FWQFGLNTTS DMFTFFSPLI NYFIISIPVF FLSSKAALEP AQVTVQSYNC 430 440 450 460 470 480 IMLASGFSQY INVSQSISDL SGYISRISTM IEVCKKVMGD TSLDIEITKL NEKDKTKSLP 490 500 510 520 530 540 NSLIINNRDT SINTDFRHIS LNEGESITLD DVTYFTPKGT QLYEKISICI KKGNNLLIMG 550 560 570 580 590 600 PSGSGKSSLI RIINGLWPFF KGSINRPENE DMFFLPQQPY LIFGTLEEQI LYPFSKKQKR 610 620 630 640 650 660 IPKSIMRELF QRFDIDYLLD RERFIKKSAQ VNDLTHNWLN QLSPGEQQLI AIIRLIYHKP 670 680 690 700 710 720 KFALMDESTS SIPQSLEERV YSVAKELGIT IISVGHRISL LKYHSTLLRF DKDKNWYLED 730 740 750 IINQNNQSNN INTINIDNNT NKIAEDSVFD

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000035 Genomic DNA. Translation: EAL67431.1.
RefSeq	XP_641430.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3392509.
GenomeReviews	Gene locus abcD3 in contig CM000152_GR.
KEGG	ddi:DDB_0215374.
Organism-specific databases
dictyBase	DDB_G0279919. abcD3.
Phylogenomic databases
HOGENOM	HBG077969.
InParanoid	Q54W20.
OMA	STHEWSS.
Family and domain databases
InterPro	IPR010509. ABC_Ald_N. IPR011527. ABC_TM_1. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF06472. ABC_membrane_2. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCD3_DICDI

Accession

Primary (citable) accession number: Q54W20

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	May 24, 2005
Last modified:	December 15, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)