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Protein

ABC transporter D family member 3

Gene

abcD3

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi540 – 547ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: dictyBase
  • ATP binding Source: UniProtKB-KW

GO - Biological processi

  • peroxisomal long-chain fatty acid import Source: dictyBase
  • transport Source: dictyBase

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter D family member 3
Alternative name(s):
ABC transporter ABCD.3
Gene namesi
Name:abcD3
ORF Names:DDB_G0279919
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0279919. abcD3.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei63 – 83HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei123 – 143HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei188 – 208HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei215 – 235HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei382 – 402HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: dictyBase
  • integral component of peroxisomal membrane Source: dictyBase

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003708511 – 750ABC transporter D family member 3Add BLAST750

Proteomic databases

PaxDbiQ54W20.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0215374.

Structurei

3D structure databases

ProteinModelPortaliQ54W20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 362ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST289
Domaini507 – 737ABC transporterPROSITE-ProRule annotationAdd BLAST231

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili334 – 370Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi15 – 27Poly-SerAdd BLAST13
Compositional biasi299 – 305Poly-His7

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0060. Eukaryota.
COG4178. LUCA.
InParanoidiQ54W20.
KOiK05678.
OMAiWGFGMIV.
PhylomeDBiQ54W20.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54W20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKNNVNNIT ETLNSSSSSS SSSGSSSDEE VKSKLNFNQT DEMLKKIKEN
60 70 80 90 100
KFDWALFKRF IKIVIILYEK PVIPLLLFLL LFGSGVSQTY ISKFTGILLS
110 120 130 140 150
NIYGSLTSGD KFLFVSSLIK GCFAIGGSAL FDAIIKFIVS IMAWNWRKTL
160 170 180 190 200
CLYIQNVYFK KSLFYKILAF DDRIDNPDQR ITSDIDNFTT LLSSIVSQCI
210 220 230 240 250
TGPMVVVYYT YLCYTTIDWY APLIVYGYFF LGYFINKLVM SPMVSINYLQ
260 270 280 290 300
DKLEGDFRYL HQRIRNFSES IALYNLSKEK QQKKSTTSVD NLDYYDDDHH
310 320 330 340 350
YHHHHDDGEE SDEYTDKTKI INRKNKNSKN KRSALLKRSN KNIKNEELLV
360 370 380 390 400
EEEQAKQQFE ALLKNKKRVI FWQFGLNTTS DMFTFFSPLI NYFIISIPVF
410 420 430 440 450
FLSSKAALEP AQVTVQSYNC IMLASGFSQY INVSQSISDL SGYISRISTM
460 470 480 490 500
IEVCKKVMGD TSLDIEITKL NEKDKTKSLP NSLIINNRDT SINTDFRHIS
510 520 530 540 550
LNEGESITLD DVTYFTPKGT QLYEKISICI KKGNNLLIMG PSGSGKSSLI
560 570 580 590 600
RIINGLWPFF KGSINRPENE DMFFLPQQPY LIFGTLEEQI LYPFSKKQKR
610 620 630 640 650
IPKSIMRELF QRFDIDYLLD RERFIKKSAQ VNDLTHNWLN QLSPGEQQLI
660 670 680 690 700
AIIRLIYHKP KFALMDESTS SIPQSLEERV YSVAKELGIT IISVGHRISL
710 720 730 740 750
LKYHSTLLRF DKDKNWYLED IINQNNQSNN INTINIDNNT NKIAEDSVFD
Length:750
Mass (Da):86,589
Last modified:May 24, 2005 - v1
Checksum:iEABB7C5ADD2A24E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000035 Genomic DNA. Translation: EAL67431.1.
RefSeqiXP_641430.1. XM_636338.1.

Genome annotation databases

EnsemblProtistsiEAL67431; EAL67431; DDB_G0279919.
GeneIDi8622315.
KEGGiddi:DDB_G0279919.

Similar proteinsi

Entry informationi

Entry nameiABCD3_DICDI
AccessioniPrimary (citable) accession number: Q54W20
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 24, 2005
Last modified: June 7, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families